Cladribine

Introduction: Cladribine

Description of Cladribine

Cladribine: An anticancer drug that belongs to the family of drugs called antimetabolites.
Source: National Institute of Health

Cladribine: A purine nucleoside antimetabolite analogue. Cladribine triphosphate, a phosphorylated metabolite of cladribine, incorporates into DNA, resulting in single-strand breaks in DNA, depletion of nicotinamide adenine dinucleotide (NAD) and adenosine triphosphate (ATP), and apoptosis. Because this agent is resistant to adenosine deaminase, an enzyme that inactivates some antineoplastic agents, it is selectively toxic to lymphocytes and monocytes which exhibit little deoxynucleotide deaminase activity. (NCI04)
Source: Diseases Database

Cladribine: An antineoplastic agent used in the treatment of lymphoproliferative diseases including hairy-cell leukemia.
Source: MeSH 2007

Terms associated with Cladribine:

Terms Similar to Cladribine:

• 2-Chloro-2'-deoxyadenosine
• 2-Chlorodeoxyadenosine

Source - MeSH 2007

Broader terms for Cladribine

• 2-Chloroadenosine
• Deoxyadenosines

Source - MeSH 2007

Hierarchical classifications of Cladribine

The following list attempts to classify Cladribine into categories where each line is subset of the next.

MeSH 2007 Hierarchy:

• Heterocyclic Compounds
  • Heterocyclic Compounds, 2-Ring
    • Purines
      • Purine Nucleosides
        • Adenosine
          • $2-Chloroadenosine$
            • Cladribine

MeSH 2007 Hierarchy

• Heterocyclic Compounds
  • Heterocyclic Compounds, 2-Ring
    • Purines
      • Purine Nucleosides
        • Adenosine
          • Deoxyadenosines
            • Cladribine

MeSH 2007 Hierarchy

• Nucleic Acids, Nucleotides, and Nucleosides
  • Nucleosides
    • Deoxyribonucleosides
      • Deoxyadenosines
        • Cladribine

MeSH 2007 Hierarchy

• Nucleic Acids, Nucleotides, and Nucleosides
  • Nucleosides
    • Purine Nucleosides
      • Adenosine
        • $2-Chloroadenosine$
          • Cladribine

MeSH 2007 Hierarchy

• Nucleic Acids, Nucleotides, and Nucleosides
  • Nucleosides
    • Purine Nucleosides
      • Adenosine
        • Deoxyadenosines
          • Cladribine

External links related to: Cladribine

• Leustat Injection. , SPC from the eMC
• CancerSourceMD.Com Drug Guide
• Leustatin Online, Description, Chemistry, Ingredients - Cladribine - RxList Monographs

Source: Diseases Database

Interesting Medical Articles:

• Symptoms of the Silent Killer Diseases
• Online Diagnosis
• Self Diagnosis Pitfalls
• Pitfalls of Online Diagnosis
• Research Your Symptoms
• Diseases & Medical Conditions
• Medical Diagnosis
• [Full list of premium articles on symptoms, diseases, and diagnosis]

Medical dictionaries:

• Medical dictionary,
• Medical Acronymns/Abbreviations

More Medical Dictionary Topics

Tunica mucosa partis intermediae urethrae masculinae

Find out more

Search to find out more about Cladribine:

powered by Search the Web Search wrongdiagnosis.com

 » Next page: Clagett

Rate This Website

What do you think about the features of this website? Take our user survey and have your say:

Website User Survey

Medical Tools & Articles:

Tools & Services:

• Bookmark this page
• Symptom Search
• Symptom Checker
• Medical Dictionary
• Give your feedback

Medical Articles:

• Disease & Treatments Search
• Misdiagnosis Center
• Full list of interesting articles

Forums & Message Boards

• Ask or answer a question at the Boards:
• I cannot get a diagnosis. Please help.
• Tell us your medical story.
• Share your misdiagnosis story.
• What is the best treatment for my condition?
• See all the Boards.

Enter your search terms Submit search form
Search The Web Search wrongdiagnosis.com

Common Health Mistakes

Symptom
Checker

Search Specialists by State and City