Cyclophosphamide

Introduction: Cyclophosphamide

Description of Cyclophosphamide

Cyclophosphamide: An anticancer drug that belongs to the family of drugs called alkylating agents.
Source: National Institute of Health

Cyclophosphamide: A synthetic alkylating agent chemically related to the nitrogen mustards with antineoplastic and immunosuppressive activities. In the liver, cyclophosphamide is converted to the active metabolites aldophosphamide and phosphoramide mustard, which bind to DNA, thereby inhibiting DNA replication and initiating cell death. (NCI04)
Source: Diseases Database

Cyclophosphamide: precursor of an alkylating nitrogen mustard antineoplastic and immunosuppressive agent; used in the treatment of lymphomas, leukemias and other cancers, and as an immunosupressive agent to prevent transplant rejection; its side effect, alopecia, has been used for defleecing sheep; may also cause sterility, birth defects, mutations, and cancer.
Source: CRISP

Cyclophosphamide: Precursor of an alkylating nitrogen mustard antineoplastic and immunosuppressive agent that must be activated in the LIVER to form the active ALDOPHOSPHAMIDE. It has been used in the treatment of LYMPHOMA and LEUKEMIA. Its side effect, ALOPECIA, has been used for defleecing sheep. Cyclophosphamide may also cause sterility, birth defects, mutations, and cancer.
Source: MeSH 2007

Drug name confusion

Because many drug names share similar spellings or sound almost identical when spoken, it is possible to mistake the name of a particular medication. Other drugs that are sometimes confused with Cyclophosphamide include:

• Cyclosporine

Cyclophosphamide: Treatments

Cyclophosphamide (treatment): See Cyclophosphamide (treatment information).

More information on treatment: Cyclophosphamide:

• Cyclophosphamide

Terms associated with Cyclophosphamide:

More specific terms for Cyclophosphamide:

• Ifosfamide

Source - MeSH 2007

Broader terms for Cyclophosphamide

• Phosphoramide Mustards

Source - MeSH 2007

• antineoplastic
• immunosuppressive
• phosphamide

Source - CRISP

The term Cyclophosphamide can be used for:

• Cytoxan

Source: CRISP

Hierarchical classifications of Cyclophosphamide

The following list attempts to classify Cyclophosphamide into categories where each line is subset of the next.

MeSH 2007 Hierarchy:

• Organic Chemicals
  • Hydrocarbons
    • Hydrocarbons, Halogenated
      • Mustard Compounds
        • Nitrogen Mustard Compounds
          • Phosphoramide Mustards
            • Cyclophosphamide

MeSH 2007 Hierarchy

• Organic Chemicals
  • Organophosphorus Compounds
    • Phosphoramide Mustards
      • Cyclophosphamide

External links related to: Cyclophosphamide

• MedDet
• CancerSourceMD.Com Drug Guide
• Cytoxan Online, Description, Chemistry, Ingredients - Cyclophosphamide - RxList Monographs
• Cyclophosphamide for multiple sclerosis (Cochrane Review)
• Cyclophosphamide for treating rheumatoid arthritis (Cochrane Review)
• Cyclophosphamide. DermNet NZ
• MDAdvice.com - Health Library - Prescription & Non-Prescription Drugs - CYCLOPHOSPHAMIDE
• RxMed: Pharmaceutical Information - PROCYTOX
• Treatment for lupus nephritis (Cochrane Review)
• Cyclophosphamide 50 Tablets , SPC from the eMC
• Cyclophosphamide frame

Source: Diseases Database

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