DNA gyrase

Introduction: DNA gyrase

Description of DNA gyrase

DNA gyrase: EC 5.99.1.3; catalyzes the twisting of relaxed, circular DNA into a super coiled state.
Source: CRISP

DNA gyrase: A bacterial DNA topoisomerase II that catalyzes ATP-dependent breakage of both strands of DNA, passage of the unbroken strands through the breaks, and rejoining of the broken strands. Gyrase binds to DNA as a heterotetramer consisting two A and two B subunits. In the presence of ATP, gyrase is able to convert relaxed circular DNA duplex into a superhelix. In the absence of ATP, supercoiled DNA is relaxed by DNA gyrase.
Source: MeSH 2007

DNA gyrase: Related Topics

These medical condition or symptom topics may be relevant to medical information for DNA gyrase:

• DNA
• Gyrase

Terms associated with DNA gyrase:

Terms Similar to DNA gyrase:

• DNA Gyrase A Subunit
• DNA Gyrase B Subunit
• gyrA Protein
• gyrB Protein

Source - MeSH 2007

Broader terms for DNA gyrase

• DNA Topoisomerases, Type II, Bacterial

Source - MeSH 2007

• isomerase

Source - CRISP

The term DNA gyrase can be used for:

• DNA topoisomerase (ATP hydrolyzing)
• EC 5.99.1.3
• type II DNA topoisomerase

Source: CRISP

Hierarchical classifications of DNA gyrase

The following list attempts to classify DNA gyrase into categories where each line is subset of the next.

MeSH 2007 Hierarchy:

• Enzymes and Coenzymes
  • Enzymes
    • Isomerases
      • DNA Topoisomerases
        • DNA Topoisomerases, Type II
          • DNA Topoisomerases, Type II, Bacterial
            • DNA Gyrase

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