Endothelin

Introduction: Endothelin

Description of Endothelin

Endothelin: A 21-amino acid peptide originally derived from endothelial cells. It is an extremely potent vasoconstrictor. Three different gene products have been identified, endothelin 1, endothelin 2, and endothelin 3; they are found in brain, kidney, and endothelium (endothelin 1), intestine (endothelin 2), and intestine and adrenal gland (endothelin 3).
Source: Stedman's Medical Spellchecker, © 2006 Lippincott Williams & Wilkins. All rights reserved.

Endothelin: 21-residue peptide paracrine hormones secreted by vascular endothelial cells which transduce neural, endocrine, and immunologic signals into vasoconstriction, and therefore plays a critical role in hypertension.
Source: CRISP

Endothelin: 21-Amino-acid peptides produced by vascular endothelial cells and functioning as potent vasoconstrictors. The endothelin family consists of three members, ENDOTHELIN-1; ENDOTHELIN-2; and ENDOTHELIN-3. All three peptides contain 21 amino acids, but vary in amino acid composition. The three peptides produce vasoconstrictor and pressor responses in various parts of the body. However, the quantitative profiles of the pharmacological activities are considerably different among the three isopeptides.
Source: MeSH 2007

Terms associated with Endothelin:

Terms Similar to Endothelin:

• Endothelium-Derived Vasoconstrictor Factors

Source - MeSH 2007

Related Topics

• Receptors, Endothelin

Source - MeSH 2007

More specific terms for Endothelin:

• Endothelin-1
• Endothelin-2
• Endothelin-3

Source - MeSH 2007

Broader terms for Endothelin

• Intercellular Signaling Peptides and Proteins

Source - MeSH 2007

• peptide hormone
• vasoconstrictor

Source - CRISP

Hierarchical classifications of Endothelin

The following list attempts to classify Endothelin into categories where each line is subset of the next.

MeSH 2007 Hierarchy:

• Amino Acids, Peptides, and Proteins
  • Peptides
    • Intercellular Signaling Peptides and Proteins
      • Endothelins

MeSH 2007 Hierarchy

• Amino Acids, Peptides, and Proteins
  • Proteins
    • Intercellular Signaling Peptides and Proteins
      • Endothelins

MeSH 2007 Hierarchy

• Biological Factors
  • Intercellular Signaling Peptides and Proteins
    • Endothelins

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• Medical Acronymns/Abbreviations

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