Factor XII: in the clotting of blood, also known as glass factor and Hageman factor When activated by glass or otherwise to its active form, factor XIIa (EC 3.4.21.38), a serine proteinase, it activates factors VII and XI and converts factor XI to its active form, factor XIa. Deficiency of factor XII results in great prolongation of the clotting time of venous blood, but only rarely in a hemorrhagic tendency; deficiency is caused by an autosomal recessive gene. SYN: glass factor, Hageman factor.
Source: Stedman's Medical Spellchecker, © 2006 Lippincott Williams & Wilkins. All rights reserved.
Factor XII: Stable blood coagulation factor activated by contact with the subendothelial surface of an injured vessel. Along with prekallikrein, it serves as the contact factor that initiates the intrinsic pathway of blood coagulation. Kallikrein activates factor XII to XIIa. Deficiency of factor XII, also called the Hageman trait, leads to increased incidence of thromboembolic disease.
Source: MeSH 2007
These medical condition or symptom topics may be relevant to medical information for Factor XII:
Source - MeSH 2007
Source - MeSH 2007
Source - MeSH 2007
Source - MeSH 2007
The following list attempts to classify Factor XII into categories where each line is subset of the next.
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