Factor XIIa: Activated form of factor XII. In the initial event in the intrinsic pathway of blood coagulation, kallikrein (with cofactor HIGH MOLECULAR WEIGHT KININOGEN) cleaves factor XII to XIIa. Factor XIIa is then further cleaved by kallikrein, plasmin, and trypsin to yield smaller factor XII fragments (Hageman-Factor fragments). These fragments increase the activity of prekallikrein to kallikrein but decrease the procoagulant activity of factor XII.
Source: MeSH 2007
These medical condition or symptom topics may be relevant to medical information for Factor XIIa:
Source - MeSH 2007
Source - MeSH 2007
Source - MeSH 2007
The following list attempts to classify Factor XIIa into categories where each line is subset of the next.
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