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Dictionary » Filgrastim
 

Filgrastim

Introduction: Filgrastim

Description of Filgrastim

Filgrastim: Human granulocyte-stimulating factor produced by recombinant DNA technology.
Source: Stedman's Medical Spellchecker, © 2006 Lippincott Williams & Wilkins. All rights reserved.

Filgrastim: A recombinant therapeutic agent which is chemically identical to or similar to the endogenous cytokine human granulocyte colony-stimulating factor (G-CSF). Produced endogenously by monocytes, fibroblasts, and endothelial cells, G-CSF binds to and activates specific cell surface receptors, stimulating neutrophil progenitor proliferation and differentiation and selected neutrophil functions. (NCI04)
Source: Diseases Database

Filgrastim: A hematopoietic growth factor which promotes proliferation and maturation of neutrophil granulocytes. Clinically it is effective in decreasing the incidence of febrile neutropenia in patients with non-myeloid malignancies receiving myelosuppressive therapy or in reducing the duration of neutropenia and neutropenia-related clinical sequelae in patients with non-myeloid malignancies undergoing myeloblastive chemotherapy followed by BMT. It has also been used in AIDS patients with CMV retinitis being treated with GANCICLOVIR. (Gelman CR, Rumack BH & Hess AJ (eds): DRUGDEX(R) System. MICROMEDEX, Inc., Englewood, Colorado (Edition expires 11/30/95)).
Source: MeSH 2007

Terms associated with Filgrastim:

Terms Similar to Filgrastim:

Source: Diseases Database

  • G-CSF Recombinant, Human Methionyl
  • Recombinant-Methionyl Human Granulocyte Colony-Stimulating Factor

Source - MeSH 2007

Broader terms for Filgrastim

Source - MeSH 2007

Hierarchical classifications of Filgrastim

The following list attempts to classify Filgrastim into categories where each line is subset of the next.

MeSH 2007 Hierarchy:

MeSH 2007 Hierarchy

MeSH 2007 Hierarchy

MeSH 2007 Hierarchy

MeSH 2007 Hierarchy

External links related to: Filgrastim

Source: Diseases Database

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