Glioblastoma multiforme

Introduction: Glioblastoma multiforme

Description of Glioblastoma multiforme

Glioblastoma multiforme (medical condition): An aggressive primary brain tumour of the glial (supporting) cells.

See also:

Glioblastoma:
  »Introduction: Glioblastoma
  »Symptoms of Glioblastoma
  »Treatments for Glioblastoma

Glioblastoma multiforme: A glioma consisting chiefly of undifferentiated anaplastic cells of astrocytic origin that show marked nuclear pleomorphism, necrosis, and vascular endothelial proliferation; frequently, tumor cells are arranged radially about an irregular focus of necrosis; these neoplasms grow rapidly, invade extensively, and occur most frequently in the cerebrum of adults. [G. glia, glue, + blastos, germ, + -oma, tumor]
Source: Stedman's Medical Spellchecker, © 2006 Lippincott Williams & Wilkins. All rights reserved.

Glioblastoma multiforme: Glioblastoma (also called Glioblastoma Multiforme) is the most malignant astrocytic tumor (WHO grade IV) and is composed of poorly differentiated neoplastic astrocytes. Histopathological features include cellular polymorphism, nuclear atypia, brisk mitotic activity, vascular thrombosis, microvascular proliferation and necrosis. Glioblastoma typically affects adults and is preferentially located in the cerebral hemispheres. Glioblastomas may develop from diffuse astrocytomas WHO grade II or anaplastic astrocytomas ('secondary glioblastoma'), but more frequently, they manifest after a short clinical history de novo, without evidence of a less malignant precursor lesion ('primary glioblastoma'). There are two histological variants of Glioblastoma: Giant Cell Glioblastoma and Gliosarcoma. (WHO)
Source: Diseases Database

Glioblastoma multiforme: malignant form of astrocytoma histologically characterized by pleomorphism of cells, nuclear atypia, microhemorrhage and necrosis; may arise in any region of the central nervous system, with a predilection for the cerebral hemispheres, basal ganglia, and commissural pathways.
Source: CRISP

Glioblastoma multiforme: Related Topics

These medical condition or symptom topics may be relevant to medical information for Glioblastoma multiforme:

• Glioblastoma

Glioblastoma multiforme as a Disease

Glioblastoma multiforme: Another name for Glioblastoma (or close medical condition association).
  »Introduction: Glioblastoma
  »Symptoms of Glioblastoma
  »Treatments for Glioblastoma

Symptoms of Glioblastoma multiforme (Glioblastoma)

Some of the symptoms of Glioblastoma multiforme incude:

• Headache
• Visual loss
• Personality change
• Paralysis or sensory loss
• Impaired speech

See full list of 23 symptoms of Glioblastoma multiforme (Glioblastoma)

Treatments for Glioblastoma multiforme (Glioblastoma)

Treatments for Glioblastoma multiforme (Glioblastoma) include:

• Surgery
• Radiotherapy

Read more about treatments for Glioblastoma multiforme

Treatment of Glioblastoma multiforme: For more treatment information about Glioblastoma multiforme, see treatment of Glioblastoma (Glioblastoma multiforme)

Glioblastoma multiforme: Related Disease Topics

These medical disease topics may be related to Glioblastoma multiforme:

• brain tumour
• glial cells
• giant cell glioblastoma
• gliosarcoma
• chemotherapy
• radiation therapy
• seizures
• nausea
• vomiting
• headache
• multiple sclerosis
• corticosteroids

Terms associated with Glioblastoma multiforme:

Terms Similar to Glioblastoma multiforme:

• Glioblastoma
• Spongioblastoma multiforme

Source: Diseases Database

Broader terms for Glioblastoma multiforme

• astrocytoma

Source - CRISP

The term Glioblastoma multiforme can be used for:

• anaplastic astrocytoma
• giant cell glioblastoma
• glioblastoma
• spongioblastoma multiforme

Source: CRISP

External links related to: Glioblastoma multiforme

• The new WHO Classification of Tumors affecting the Central Nervous System
• National Cancer Institute - Adult Brain Tumor Treatment
• eMedicine - Glioblastoma Multiforme : Article by Jeffrey Bruce, MD
• glioblastoma multiforme (GBM)
• eMedicine - Glioblastoma Multiforme : Article by ABM Salah Uddin, MD

Source: Diseases Database

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Medical dictionaries:

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