Interleukin-11: A cytokine and growth factor derived from bone marrow stromal cells (endothelial cells, macrophages, and preadipocytes) that stimulates increased plasma concentrations of acute-phase proteins and is a growth factor with multiple hematopoietic effects.
Source: Stedman's Medical Spellchecker, © 2006 Lippincott Williams & Wilkins. All rights reserved.
Interleukin-11: A recombinant therapeutic agent which is chemically identical to or similar to the endogenous cytokine interleukin 11 (IL-11). Secreted by bone marrow stromal cells and a number of mesenchymal cells, IL-11 binds to and activates its cell-surface receptor, promoting primary and secondary immune responses, modulating antigen-specific antibody reactions, and preventing apoptotic cell death. This agent also stimulates the T-cell-dependent development of IgG-secreting B-cells in spleen cell cultures and may be an important regulator of megakaryocytopoiesis. (NCI04)
Source: Diseases Database
Interleukin-11: cloned from a primate stromal cell line; plays a role in megakaryocyte proliferation and B cell differentiation.
Source: CRISP
Interleukin-11: A lymphohematopoietic cytokine that plays a role in regulating the proliferation of ERYTHROID PROGENITOR CELLS. It induces maturation of MEGAKARYOCYTES which results in increased production of BLOOD PLATELETS. Interleukin-11 was also initially described as an inhibitor of ADIPOGENESIS of cultured preadipocytes.
Source: MeSH 2007
Source: Diseases Database
Source - MeSH 2007
Source - MeSH 2007
Source - CRISP
Source: CRISP
The following list attempts to classify Interleukin-11 into categories where each line is subset of the next.
Source: Diseases Database
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