Li-Fraumeni syndrome (medical condition): A rare inherited disorder characterized by tumor development by young adulthood.
See also:
Li-Fraumeni syndrome:
»Introduction: Li-Fraumeni syndrome
»Symptoms of Li-Fraumeni syndrome
Li-Fraumeni syndrome: A rare, inherited predisposition to multiple cancers, caused by an alteration in the p53 tumor suppressor gene.
Source: National Institute of Health
Li-Fraumeni syndrome: familial syndrome of early breast carcinoma associated with soft tissue sarcomas and other tumors.
Source: Diseases Database
Li-Fraumeni syndrome: rare autosomal dominant syndrome characterized by mesenchymal and epithelial neoplasms at multiple sites; a point mutation of the p53 tumor suppressor gene apparently predisposes family members who inherit it to develop certain cancers including early breast carcinoma; associated with soft tissue sarcomas and other tumors.
Source: CRISP
Li-Fraumeni syndrome: Rare autosomal dominant syndrome characterized by mesenchymal and epithelial neoplasms at multiple sites. MUTATION of the p53 tumor suppressor gene, a component of the DNA DAMAGE response pathway, apparently predisposes family members who inherit it to develop certain cancers. The spectrum of cancers in the syndrome was shown to include, in addition to BREAST CANCER and soft tissue sarcomas (SARCOMA); BRAIN TUMORS; OSTEOSARCOMA; LEUKEMIA; and ADRENOCORTICAL CARCINOMA.
Source: MeSH 2007
These medical condition or symptom topics may be relevant to medical information for Li-Fraumeni syndrome:
Li-Fraumeni syndrome is listed as a "rare disease" by the Office of
Rare Diseases (ORD) of the National Institutes of Health
(NIH). This means that Li-Fraumeni syndrome, or a subtype of Li-Fraumeni syndrome,
affects less than 200,000 people in the US population.
Source - National Institutes of Health (NIH)
Ophanet, a consortium of European partners,
currently defines a condition rare when if affects 1 person per 2,000.
They list Li-Fraumeni syndrome as a "rare disease".
Source - Orphanet
Li-Fraumeni syndrome (medical condition): See Li-Fraumeni syndrome (disease information).
»Introduction: Li-Fraumeni syndrome
»Symptoms of Li-Fraumeni syndrome
These medical disease topics may be related to Li-Fraumeni syndrome:
Source - NIH
Source - MeSH 2007
Source - MeSH 2007
Source - CRISP
Source: CRISP
The following list attempts to classify Li-Fraumeni syndrome into categories where each line is subset of the next.
Source: Diseases Database
Search to find out more about Li-Fraumeni syndrome:
|
What do you think about the features of this website? Take our user survey and have your say:
Tools & Services:
Medical Articles:
Search Specialists by State and City
By using this site you agree to our Terms of Use. Information provided on this site is for informational purposes only; it is not intended as a substitute for advice from your own medical team. The information on this site is not to be used for diagnosing or treating any health concerns you may have - please contact your physician or health care professional for all your medical needs. Please see our Terms of Use.
Copyright © 2009 Health Grades Inc. All rights reserved.
