Megestrol acetate: An orally available synthetic derivative of progesterone administered as an acetate salt with antiestrogenic activity. As a do all progestins, medroxyprogesterone binds to and activates nuclear progesterone receptors which bind to and activate target genes for transcription. As an antiestrogen, this agent may inhibit the growth-stimulating effects of estrogen on estrogen-sensitive tumor cells. Megestrol may also stimulate appetite in cachectic subjects. (NCI04)
Source: Diseases Database
Megestrol acetate: Megestrol acetate is a progestogen with actions and uses similar to those of the progestogens in general. It also has anti-androgenic properties. It is given by mouth in the palliative treatment or as an adjunct to other therapy in endometrial carcinoma and in breast cancer. Megestrol acetate has been approved to treat anorexia and cachexia. (From Reynolds JEF(Ed): Martindale: The Extra Pharmacopoeia (electronic version). Micromedex, Inc, Englewood, CO, 1995).
Source: MeSH 2007
These medical condition or symptom topics may be relevant to medical information for Megestrol acetate:
The following list attempts to classify Megestrol acetate into categories where each line is subset of the next.
Source: Diseases Database
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