Mutation

Introduction: Mutation

Description of Mutation

Mutation: An error or change in a gene or DNA sequence.

Mutation: (1) A change in the chemistry of a gene that is perpetuated in subsequent divisions of the cell in which it occurs; a change in the sequence of base pairs in the chromosomal molecule. (2) De Vries, term for the sudden production of a species, as distinguished from variation. [L. muto, pp. -atus, to change]
Source: Stedman's Medical Spellchecker, © 2006 Lippincott Williams & Wilkins. All rights reserved.

Mutation: Any change in the DNA of a cell. Mutations may be caused by mistakes during cell division, or they may be caused by exposure to DNA-damaging agents in the environment. Mutations can be harmful, beneficial, or have no effect. If they occur in cells that make eggs or sperm, they can be inherited; if mutations occur in other types of cells, they are not inherited. Certain mutations may lead to cancer or other diseases.
Source: National Institute of Health

Mutation: Any detectable and heritable change in the genetic material that causes a change in the GENOTYPE and which is transmitted to daughter cells and to succeeding generations.
Source: MeSH 2007

Terms associated with Mutation:

Related Topics

• Antimutagenic Agents
• DNA Damage
• Mutagenesis
• Mutagens
• Polymorphism, Restriction Fragment Length
• Suppression, Genetic

Source - MeSH 2007

More specific terms for Mutation:

• Chromosome Aberrations
• Gene Amplification
• Suppression, Genetic
• Frameshift Mutation
• Point Mutation
• Sequence Deletion
• Germ-Line Mutation
• Codon, Nonsense
• Mutation, Missense
• Base Pair Mismatch
• Gene Duplication
• Allelic Imbalance
• DNA Repeat Expansion
• Genomic Instability

Source - MeSH 2007

Broader terms for Mutation

• Variation (Genetics)

Source - MeSH 2007

The following terms can be used for Mutation

• gene mutation

Source: CRISP

Hierarchical classifications of Mutation

The following list attempts to classify Mutation into categories where each line is subset of the next.

MeSH 2007 Hierarchy:

• Genetic Phenomena
  • Variation (Genetics)
    • Mutation

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