Nicotine: A poisonous volatile alkaloid derived from tobacco (Nicotiana spp.) and responsible for many of the effects of tobacco; it first stimulates (small doses), then depresses (large doses) at autonomic ganglia and myoneural junctions. Its principal urinary metabolite is cotinine. Nicotine is an important tool in physiologic and pharmacologic investigation, is used as an insecticide and fumigant, and forms salts with most acids.tobacco. [Nicotiana, genus name of botanical source, + - ine]Nicotine in inhaled tobacco smoke or in smokeless tobacco applied to buccal or nasal mucosa enters the circulation within seconds, causing an increase in heart rate, ventricular stroke volume, and myocardial oxygen consumption, as well as euphoria, heightened alertness, and a sense of relaxation. Nicotine use is powerfully addictive, readily leading to habituation, tolerance, and dependency. Withdrawal from nicotine causes restlessness, irritability, anxiety, difficulty concentrating, and craving for nicotine. Addiction to nicotine is the reason for most tobacco use and is thus directly responsible for the resulting morbidity and mortality.
Source: Stedman's Medical Spellchecker, © 2006 Lippincott Williams & Wilkins. All rights reserved.
Nicotine: An addictive, poisonous chemical found in tobacco. It can also be made in the laboratory. When it enters the body, nicotine causes an increased heart rate and use of oxygen by the heart, and a sense of well-being and relaxation. It is also used as an insecticide.
Source: National Institute of Health
Nicotine: An addictive CNS stimulant found in the tobacco plant that causes either ganglionic stimulation by depolarization in low doses or ganglionic blockage in high doses. (NCI)
Source: Diseases Database
Nicotine: very poisonous alkaloid; the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and ultimately blocks synaptic transmission; nicotine is important medically because of its presence in tobacco smoke, and is also used as an insecticide.
Source: CRISP
Nicotine: Nicotine is highly toxic alkaloid. It is the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and ultimately blocks synaptic transmission. Nicotine is also important medically because of its presence in tobacco smoke.
Source: MeSH 2007
Source - CRISP
Source - MeSH 2007
Source - CRISP
Source: CRISP
Source: CRISP
The following list attempts to classify Nicotine into categories where each line is subset of the next.
Source: Diseases Database
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