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Dictionary » Nonsteroidal anti-inflammatory drug

Nonsteroidal anti-inflammatory drug

Introduction: Nonsteroidal anti-inflammatory drug

Description of Nonsteroidal anti-inflammatory drug

Nonsteroidal anti-inflammatory drug: NSAID. A drug that decreases fever, swelling, pain, and redness.
Source: National Institute of Health

Nonsteroidal anti-inflammatory drug: an anti-inflammatory drug that does not contain steroids; "NSAIDs inhibit the activity of both Cox-1 and Cox-2 enzymes".
Source: WordNet 2.1

Nonsteroidal anti-inflammatory drug: Anti-inflammatory agents that are not steroids. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions. They are used primarily in the treatment of chronic arthritic conditions and certain soft tissue disorders associated with pain and inflammation. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects. Certain NSAIDs also may inhibit lipoxygenase enzymes or phospholipase C or may modulate T-cell function. (AMA Drug Evaluations Annual, 1994, p 1814-5)
Source: Diseases Database