Osteoprotegerin

Introduction: Osteoprotegerin

Description of Osteoprotegerin

Osteoprotegerin: osteoclastogenesis inhibitor; secreted protein that regulates bone density; member of the TNF receptor superfamily
Source: CRISP

Osteoprotegerin: A secreted member of the TNF receptor superfamily that negatively regulates osteoclastogenesis. It is a soluble decoy receptor of RANK LIGAND that inhibits both CELL DIFFERENTIATION and function of OSTEOCLASTS by inhibiting the interaction between RANK LIGAND and RECEPTOR ACTIVATOR OF NUCLEAR FACTOR-KAPPA B.
Source: MeSH 2007

Terms associated with Osteoprotegerin:

Terms Similar to Osteoprotegerin:

• Osteoclastogenesis Inhibitory Factor
• Receptors, Tumor Necrosis Factor, Member 11b
• Tumor Necrosis Factor Receptor Superfamily, Member 11b

Source - MeSH 2007

Broader terms for Osteoprotegerin

• Tumor Necrosis Factor Decoy Receptors

Source - MeSH 2007

• cytokine receptor

Source - CRISP

The term Osteoprotegerin can be used for:

• osteoclastogenesis inhibitory factor
• tumor necrosis factor receptor 11b

Source: CRISP

Other terms that may be related to Osteoprotegerin:

• musculoskeletal regeneration

Source: CRISP

The description of Osteoprotegerin may also be used for the following terms:

• RANK protein

Source: CRISP

Hierarchical classifications of Osteoprotegerin

The following list attempts to classify Osteoprotegerin into categories where each line is subset of the next.

MeSH 2007 Hierarchy:

• Amino Acids, Peptides, and Proteins
  • Proteins
    • Membrane Proteins
      • Receptors, Cell Surface
        • Receptors, Immunologic
          • Receptors, Cytokine
            • Receptors, Tumor Necrosis Factor
              • Tumor Necrosis Factor Decoy Receptors
                • Osteoprotegerin

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