Phenylbutyrate: An orally active derivative of the short-chain fatty acid butyrate with potential antineoplastic activity. 4-Phenylbutyrate inhibits histone deacetylase, resulting in cell cycle gene expression modulation, reduced cell proliferation, increased cell differentiation, and apoptosis. This agent also initiates fragmentation of genomic DNA, resulting in decreased DNA synthesis and the inhibition of tumor cell migration and invasion. (NCI04)
Source: Diseases Database
Phenylbutyrate: cytostatic, apoptosis inducing agent; effects cell differentiation.
Source: CRISP
Source: Diseases Database
Source - MeSH 2007
Source - CRISP
Source: CRISP
The following list attempts to classify Phenylbutyrate into categories where each line is subset of the next.
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