Proopiomelanocortin

Introduction: Proopiomelanocortin

Description of Proopiomelanocortin

Proopiomelanocortin: precursor polypeptide from which ACTH, MSH, and beta-lipotropin are produced by posttranslational cleavage.
Source: CRISP

Proopiomelanocortin: A 30-kDa protein synthesized primarily in the ANTERIOR PITUITARY GLAND and the HYPOTHALAMUS. It is also found in the skin and other peripheral tissues. Depending on species and tissues, POMC is cleaved by PROHORMONE CONVERTASES yielding various active peptides including ACTH; BETA-LIPOTROPIN; ENDORPHINS; MELANOCYTE-STIMULATING HORMONES; and others (GAMMA-LPH; CORTICOTROPIN-LIKE INTERMEDIATE LOBE PEPTIDE; N-terminal peptide of POMC or NPP).
Source: MeSH 2007

Terms associated with Proopiomelanocortin:

Terms Similar to Proopiomelanocortin:

• POMC
• Pro-Opiocortin

Source - MeSH 2007

More specific terms for Proopiomelanocortin:

• Adrenocorticotropic Hormone
• alpha-MSH
• beta-Endorphin
• beta-Lipotropin
• alpha-Endorphin
• gamma-Endorphin
• beta-MSH
• gamma-MSH
• Melanocortins
• Corticotropin-Like Intermediate Lobe Peptide
• gamma-Lipotropin

Source - MeSH 2007

Broader terms for Proopiomelanocortin

• Hypothalamic Hormones
• Pituitary Hormones, Anterior
• Protein Precursors

Source - MeSH 2007

• pituitary hormone

Source - CRISP

The description of Proopiomelanocortin may also be used for the following terms:

• POMC

Source: CRISP

Hierarchical classifications of Proopiomelanocortin

The following list attempts to classify Proopiomelanocortin into categories where each line is subset of the next.

MeSH 2007 Hierarchy:

• Hormones, Hormone Substitutes, and Hormone Antagonists
  • Hormones
    • Peptide Hormones
      • Hypothalamic Hormones
        • Pro-Opiomelanocortin

MeSH 2007 Hierarchy

• Hormones, Hormone Substitutes, and Hormone Antagonists
  • Hormones
    • Peptide Hormones
      • Pituitary Hormones
        • Pituitary Hormones, Anterior
          • Pro-Opiomelanocortin

MeSH 2007 Hierarchy

• Amino Acids, Peptides, and Proteins
  • Peptides
    • Neuropeptides
      • Hypothalamic Hormones
        • Pro-Opiomelanocortin

MeSH 2007 Hierarchy

• Amino Acids, Peptides, and Proteins
  • Peptides
    • Peptide Hormones
      • Hypothalamic Hormones
        • Pro-Opiomelanocortin

MeSH 2007 Hierarchy

• Amino Acids, Peptides, and Proteins
  • Peptides
    • Peptide Hormones
      • Pituitary Hormones
        • Pituitary Hormones, Anterior
          • Pro-Opiomelanocortin

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