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Protein S deficiency
Introduction: Protein S deficiency
Description of Protein S deficiency
Protein S deficiency (medical condition):
A genetic condition where a person faces an increased risk of blood clot formation. It is characterized by a deficiency of functioning protein S which is a protein needed to regulate the blood clotting process. The homozygous form of the condition carries a much higher risk of thrombosis with severe thrombosis often occurring at birth.
See also Protein S deficiency:
»Introduction: Protein S deficiency
»Symptoms of Protein S deficiency
Protein S deficiency: An autosomal dominant disorder showing decreased levels of plasma protein S antigen or activity, associated with venous thrombosis and pulmonary embolism. PROTEIN S is a vitamin K-dependent plasma protein that inhibits blood clotting by serving as a cofactor for activated PROTEIN C (also a vitamin K-dependent protein), and the clinical manifestations of its deficiency are virtually identical to those of protein C deficiency. Treatment with heparin for acute thrombotic processes is usually followed by maintenance administration of coumarin drugs for the prevention of recurrent thrombosis. (From Harrison's Principles of Internal Medicine, 12th ed, p1511; Wintrobe's Clinical Hematology, 9th ed, p1523)
Source: Diseases Database
Protein S deficiency: An autosomal dominant disorder showing decreased levels of plasma protein S antigen or activity, associated with venous thrombosis and pulmonary embolism. PROTEIN S is a vitamin K-dependent plasma protein that inhibits blood clotting by serving as a cofactor for activated PROTEIN C (also a vitamin K-dependent protein), and the clinical manifestations of its deficiency are virtually identical to those of protein C deficiency. Treatment with heparin for acute thrombotic processes is usually followed by maintenance administration of coumarin drugs for the prevention of recurrent thrombosis. (From Harrison's Principles of Internal Medicine, 12th ed, p1511; Wintrobe's Clinical Hematology, 9th ed, p1523).
Source: MeSH 2007
Protein S deficiency: Rare Disease
Ophanet
Ophanet, a consortium of European partners,
currently defines a condition rare when if affects 1 person per 2,000.
They list Protein S deficiency as a "rare disease".
Source - Orphanet
Protein S deficiency as a Disease
Protein S deficiency (medical condition): See Protein S deficiency (disease information).
»Introduction: Protein S deficiency
»Symptoms of Protein S deficiency
More information on medical condition: Protein S deficiency:
- Information about Protein S deficiency
- Basic Summary for Protein S deficiency
- Symptoms of Protein S deficiency
- Complications of Protein S deficiency
Protein S deficiency as a Symptom
Protein S deficiency (symptom): Another name for Decreased protein S.
»Introduction: Decreased protein S
»Causes of Decreased protein S
Protein S deficiency (symptom): A protein which is necessary to prevent the clotting cascade.
More information on symptom: Decreased protein S:
Hierarchical classifications of Protein S deficiency
The following list attempts to classify Protein S deficiency into categories where each line is subset of the next.
MeSH 2007 Hierarchy:
MeSH 2007 Hierarchy
MeSH 2007 Hierarchy
External links related to: Protein S deficiency
Source: Diseases Database
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