Ribonucleotide reductase

Introduction: Ribonucleotide reductase

Description of Ribonucleotide reductase

Ribonucleotide reductase: a protein complex that converts ribonucleotide diphosphates (NDPs) such as ADP and CDP to 2'-deoxyribonucleotide diphosphates (dNDPs) such as dADP and dCDP. This complex requires thioredoxin, thioredoxin reductase, and NADPH. It is crucial for DNA synthesis.
Source: Stedman's Medical Spellchecker, © 2006 Lippincott Williams & Wilkins. All rights reserved.

Ribonucleotide reductase: EC 1.17.4; interconverts ribonucleotides (RNA precursors) and deoxyribonucleotides (DNA precursors); rate limiting to DNA replication in rapidly dividing cells, and therefore a potential target of antineoplastic drugs.
Source: CRISP

Ribonucleotide reductase: Related Topics

These medical condition or symptom topics may be relevant to medical information for Ribonucleotide reductase:

• Ribonucleotide
• Reductase

Terms associated with Ribonucleotide reductase:

More specific terms for Ribonucleotide reductase:

• Ribonucleoside Diphosphate Reductase

Source - MeSH 2007

Broader terms for Ribonucleotide reductase

• Oxidoreductases

Source - MeSH 2007

• iron sulfur protein
• oxidoreductase

Source - CRISP

The description of Ribonucleotide reductase may also be used for the following terms:

• EC 1.17.4

Source: CRISP

Hierarchical classifications of Ribonucleotide reductase

The following list attempts to classify Ribonucleotide reductase into categories where each line is subset of the next.

MeSH 2007 Hierarchy:

• Enzymes and Coenzymes
  • Enzymes
    • Oxidoreductases
      • Ribonucleotide Reductases

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Medical dictionaries:

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• Medical Acronymns/Abbreviations

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