Schick test: A test used to determine a person's susceptibility to diphtheria. It involves noting any changes in the skin where a small amount of diphtheria toxin is injected.
Schick test: a test for susceptibility to Corynebacterium diphtheriae toxin: 0.1 mL of Schick test toxin is injected into the skin of one forearm (test site) and the same quantity of the same, but heat-inactivated, material into the skin of the other forearm (control site); those with toxin-neutralizing antibodies either will have no reaction at either injection site (negative test) or may have a pseudoreaction due to antibodies for substances (antigens) in the test materials other than diphtheria toxin; people lacking toxin-neutralizing antibodies may have a positive reaction, which consists of an area of redness appearing 24-36 hours at the test site only and persisting for 4-5 days. SYN: Schick method.
Source: Stedman's Medical Spellchecker, © 2006 Lippincott Williams & Wilkins. All rights reserved.
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