Sipple's syndrome

Introduction: Sipple's syndrome

Description of Sipple's syndrome

Sipple's syndrome (medical condition): Rare inherited disease causing tumors in multiple glands. See also Multiple endocrine neoplasia type 2:
  »Introduction: Multiple endocrine neoplasia type 2
  »Symptoms of Multiple endocrine neoplasia type 2

Sipple's syndrome: A type of multiple endocrine neoplasia characterized by a virtually 100% incidence of medullary thyroid carcinoma, a 50% incidence of pheochromocytoma, and a lesser incidence of parathyroid adenomas associated with hyperparathyroidism. The condition is always transmitted through autosomal dominant inheritance. Genetic testing can identify individuals with the trait in early infancy. Treatment is usually excision of the enlarged parathyroid glands. (From Holland et al., Cancer Medicine, 3d ed, pp1172-75)
Source: Diseases Database

Sipple's syndrome as a Disease

Sipple's syndrome: Another name for Multiple endocrine neoplasia type 2 (or close medical condition association).
  »Introduction: Multiple endocrine neoplasia type 2
  »Symptoms of Multiple endocrine neoplasia type 2

Sipple's syndrome: Sipple's syndrome is listed as a type of (or associated with) the following medical conditions in our database: Thyroid disorders, Multiple endocrine neoplasia, Genetic Disease

Symptoms of Sipple's syndrome (Multiple endocrine neoplasia type 2)

Some of the symptoms of Sipple's syndrome incude:

• Abdominal pain
• Abdominal distension
• Anorexia
• Nausea
• Polyuria

See full list of 25 symptoms of Sipple's syndrome (Multiple endocrine neoplasia type 2)

Terms associated with Sipple's syndrome:

Terms Similar to Sipple's syndrome:

• Multiple endocrine neoplasia type 2a
• MEN type 2a

Source: Diseases Database

The following terms can be used for Sipple's syndrome

• multiple endocrine neoplasia

Source: CRISP

External links related to: Sipple's syndrome

• OMIM - MULTIPLE ENDOCRINE NEOPLASIA, TYPE II; MEN2
• GeneReviews: Multiple Endocrine Neoplasia Type 2
• Sipple's syndrome (www.whonamedit.com)
• MEN-2 (Sipple) syndrome
• eMedicine - Multiple Endocrine Neoplasia, Type 2 : Article by Melanie L Richards, MD

Source: Diseases Database

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