Stavudine: A synthetic nucleoside, analog of didehydro-3-deoxythymidine with potent antiretroviral activity. In vivo, stavudine is phosphorylated by cellular kinases to the active metabolite stavudine triphosphate; this metabolite inhibits the activity of HIV reverse transcriptase both by competing with the natural substrate deoxythymidine triphosphate and by incorporation into viral DNA causing a termination of DNA chain elongation (due to the lack the essential 3'-OH group). (NCI04)
Source: Diseases Database
Stavudine: nucleoside analog; used as an antiviral agent.
Source: CRISP
Stavudine: A dideoxynucleoside analog that inhibits reverse transcriptase and has in vitro activity against HIV.
Source: MeSH 2007
Source: Diseases Database
Source - CRISP
Source - MeSH 2007
Source - MeSH 2007
Source - CRISP
Source: CRISP
Source: CRISP
The following list attempts to classify Stavudine into categories where each line is subset of the next.
Source: Diseases Database
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