T lymphocyte: a lymphocyte formed in the bone marrow from which it migrates to the thymic cortex to become an immunologically competent cell; T lymphocytes have long lifespans (months to years) and are responsible for cell-mediated immunity; T lymphocytes form rosettes with sheep erythrocytes and differentiate and divide in the presence of transforming agents (mitogens); T lymphocytes have characteristic T cell receptor-CD3 complexes as surface markers and may be further categorized by function, such as helper and cytotoxic.B lymphocyte. SYN: T cell.
Source: Stedman's Medical Spellchecker, © 2006 Lippincott Williams & Wilkins. All rights reserved.
T lymphocyte: lymphocytes responsible for cell-mediated immunity, formed when lymphocytes circulate through the thymus gland and differentiate to thymocytes; when exposed to an antigen, they divide rapidly and produce large numbers of new T cells sensitized to that antigen.
Source: CRISP
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