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Dictionary » Tamoxifen
 

Tamoxifen

Introduction: Tamoxifen

Description of Tamoxifen

Tamoxifen (medical condition): Tamoxifen is a drug used to reduce the risk of developing breast cancer but is also deemed to be carcinogenic to humans as it increases the risk of developing other cancers. The carcinogenicity of the substance may be influenced by the duration and level of exposure. Tamoxifen exposure is associated mainly with an increased risk of developing uterine cancer.

See also:

Human carcinogen -Tamoxifen:
  »Introduction: Human carcinogen -Tamoxifen
  »Symptoms of Human carcinogen -Tamoxifen

Tamoxifen: A drug used to treat breast cancer, and to prevent it in women who are at a high risk of developing breast cancer. Tamoxifen blocks the effects of the hormone estrogen in the breast. It belongs to the family of drugs called antiestrogens.
Source: National Institute of Health

Tamoxifen: An antineoplastic nonsteroidal selective estrogen receptor modulator (SERM). Tamoxifen competitively inhibits the binding of estradiol to estrogen receptors, thereby preventing the receptor from binding to the estrogen-response element on DNA. The result is a reduction in DNA synthesis and cellular response to estrogen. In addition, tamoxifen up-regulates the production of transforming growth factor B (TGFb), a factor that inhibits tumor cell growth, and down-regulates insulin-like growth factor 1 (IGF-1), a factor that stimulates breast cancer cell growth. (NCI04)
Source: Diseases Database

Tamoxifen: selective estrogen receptor modulator; it is agonist for bone tissue and cholesterol metabolism but antagonist in mammary and uterine tissues.
Source: CRISP

Tamoxifen: One of the SELECTIVE ESTROGEN RECEPTOR MODULATORS with tissue-specific activities. Tamoxifen acts as an anti-estrogen (inhibiting agent) in the mammary tissue, but as an estrogen (stimulating agent) in cholesterol metabolism, bone density, and cell proliferation in the ENDOMETRIUM.
Source: MeSH 2007

Drug name confusion

Because many drug names share similar spellings or sound almost identical when spoken, it is possible to mistake the name of a particular medication. Other drugs that are sometimes confused with Tamoxifen include:

Tamoxifen as a Disease

Tamoxifen: Another name for Human carcinogen -Tamoxifen (or close medical condition association).
  »Introduction: Human carcinogen -Tamoxifen
  »Symptoms of Human carcinogen -Tamoxifen

Symptoms of Tamoxifen (Human carcinogen -Tamoxifen)

Some of the symptoms of Tamoxifen incude:

  • Increased risk of cancer - particularly uterine cancer

Read more about symptoms of Tamoxifen (Human carcinogen -Tamoxifen)

Terms associated with Tamoxifen:

More specific terms for Tamoxifen:

Source - MeSH 2007

Broader terms for Tamoxifen

Source - MeSH 2007

Source - CRISP

The term Tamoxifen can be used for:

Source: CRISP

Hierarchical classifications of Tamoxifen

The following list attempts to classify Tamoxifen into categories where each line is subset of the next.

MeSH 2007 Hierarchy:

External links related to: Tamoxifen

Source: Diseases Database

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