Thromboplastin

Introduction: Thromboplastin

Description of Thromboplastin

Thromboplastin: A substance present in tissues, platelets, and leukocytes necessary for the coagulation of blood; in the presence of calcium ions thromboplastin is necessary for the conversion of prothrombin to thrombin, an important step in coagulation of blood. It is now generally believed that thromboplastin activity may be developed through blood (intrinsic) or tissue (extrinsic) systems. Tissue thromboplastin (factor III) interacts with factor VII and calcium to activate factor X; active factor X combines with factor V in the presence of calcium and phospholipid to produce thromboplastin activity (also commonly called thromboplastin). SYN: platelet tissue factor, thrombokinase, thrombozyme, tissue factor, zymoplastic substance.
Source: Stedman's Medical Spellchecker, © 2006 Lippincott Williams & Wilkins. All rights reserved.

Thromboplastin: coagulation factor important in the formation of extrinsic prothrombin converting principle in the extrinsic pathway of blood coagulation; derived from several sources in the body including brain and lungs.
Source: CRISP

Thromboplastin: Constituent composed of protein and phospholipid that is widely distributed in many tissues. It serves as a cofactor with factor VIIa to activate factor X in the extrinsic pathway of blood coagulation.
Source: MeSH 2007

Terms associated with Thromboplastin:

Terms Similar to Thromboplastin:

• Antigens, CD142
• CD142 Antigens
• Coagulation Factor III
• Factor III
• Tissue Factor
• Tissue Thromboplastin

Source - MeSH 2007

Related Topics

• Coagulants

Source - MeSH 2007

Broader terms for Thromboplastin

• Blood Coagulation Factors

Source - MeSH 2007

• clotting factor

Source - CRISP

The term Thromboplastin can be used for:

• coagulation factor III
• prothrombin activator
• tissue factor

Source: CRISP

Hierarchical classifications of Thromboplastin

The following list attempts to classify Thromboplastin into categories where each line is subset of the next.

MeSH 2007 Hierarchy:

• Amino Acids, Peptides, and Proteins
  • Proteins
    • Blood Proteins
      • Blood Coagulation Factors
        • Thromboplastin

MeSH 2007 Hierarchy

• Biological Factors
  • Blood Coagulation Factors
    • Thromboplastin

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Medical dictionaries:

• Medical dictionary,
• Medical Acronymns/Abbreviations

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