Thyroglobulin: [MIM*188450] (1) A protein that contains precursors of thyroid hormone usually stored in the colloid within the thyroid follicles; biosynthesis of thyroid hormone entails iodination of the l-tyrosyl moieties of this protein and the combination of two iodotyrosines to form thyroxine, the fully iodinated thyronine; secretion of thyroid hormone requires proteolytic degradation of thyroglobulin, with the attendant release of free hormone; a defect in thyroglobulin metabolism will lead to hypothyroidism. SYN: iodoglobulin, thyroprotein (1). (2) A substance obtained by the fractionation of thyroid glands from the hog, Sus scrofa, containing not less than 0.7% of total iodine; used as a thyroid hormone in the treatment of hypothyroidism.
Source: Stedman's Medical Spellchecker, © 2006 Lippincott Williams & Wilkins. All rights reserved.
Thyroglobulin: intracellular iodoglycoprotein precursor of thyroxine and triiodothyronine.
Source: CRISP
Source - MeSH 2007
Source - CRISP
Source: CRISP
The following list attempts to classify Thyroglobulin into categories where each line is subset of the next.
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