Urokinase: SYN: plasminogen activator.
Source: Stedman's Medical Spellchecker, © 2006 Lippincott Williams & Wilkins. All rights reserved.
Urokinase: Encoded by human PLAU Gene (Peptidase S1 Family), 431-aa 48.5-kD single-chain Urokinase precursor contains a kringle and an EGF-like domain. A potent activator of plasminogen to plasmin conversion by Arg-Val cleavage, the two-chain serine protease is composed of disulfide-linked A (18,000 D) and B (33,000 D) chains that arise from precursor Lys(158)-Ile(159) cleavage by plasmin. Urokinase occurs in high and low mass forms, each consisting of A and B chains. The high mass form contains a long A chain; cleavage after residue 155 in the low mass form yields a short A1 chain. Urokinase is immunologically unrelated to TPA. (from LocusLink, Swiss-Prot, OMIM, and NCI)
Source: Diseases Database
Urokinase: EC 3.4.21.73.
Source: CRISP
Source: Diseases Database
Source - CRISP
Source: CRISP
Source: Diseases Database
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