Valproate

Introduction: Valproate

Description of Valproate

Valproate: A synthetic derivative of propylpentanoic acid with antiepileptic properties and potential antineoplastic and antiangiogenesis activities. In epilepsy, valproic acid appears to act by increasing the concentration of gamma-aminobutyric acid (GABA) in the brain. The antitumor and antiangiogenesis activities of this agent may be related to the inhibition of histone deacetylases and nitric oxide synthase, resulting in decreased production of nitric oxide. (NCI04)
Source: Diseases Database

Valproate: fatty acid with anticonvulsant properties.
Source: CRISP

Terms associated with Valproate:

Terms Similar to Valproate:

• Valproic acid
• Divalproex

Source: Diseases Database

Broader terms for Valproate

• anticonvulsant
• carboxylate

Source - CRISP

The term Valproate can be used for:

• 2 propylvalerate

Source: CRISP

External links related to: Valproate

• Search Jablonski's Syndromes Database
• Newly Approved Drug Therapies (133): Depakote (Divalproex Sodium), Abbott Laboratories
• Phenytoin versus valproate monotherapy for partial onset seizures and generalized onset tonic-clonic seizures (Cochrane Review)
• Convulex 500 mg Capsules , SPC from the eMC
• eMedicine - Toxicity, Valproate : Article by Timothy Wiegand, MD
• Depakote Online, Description, Chemistry, Ingredients - Divalproex Sodium - RxList Monographs
• Valproic Acid frame
• MDAdvice.com - Health Library - Prescription & Non-Prescription Drugs - DIVALPROEX
• Valproic acid (PIM 551)
• MedDet
• Valproic acid, valproate and divalproex in the maintenance treatment of bipolar disorder (Cochrane Review)
• Valproate for schizophrenia (Cochrane Review)
• Valproate preparations for agitation in dementia (Cochrane Review)
• Convulex 150 mg Capsules , SPC from the eMC
• Carbamazepine versus valproate monotherapy for epilepsy (Cochrane Review)
• Ethosuximide, sodium valproate or lamotrigine for absence seizures in children and adolescents (Cochrane Review)
• Convulex 300 mg Capsules , SPC from the eMC
• Depakote tablets , SPC from the eMC
• Valproic Acid
• Bipolar disorder - new drugs (No. 66)
• Valproate for acute mood episodes in bipolar disorder (Cochrane Review)
• Early versus late antiepileptic drug withdrawal for people with epilepsy in remission (Cochrane Review)
• Divalproex Sodium
• Depacon Online, Description, Chemistry, Ingredients - Valproate Sodium - RxList Monographs
• Depakene Online, Description, Chemistry, Ingredients - Valproic Acid - RxList Monographs

Source: Diseases Database

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