Valproic acid

Introduction: Valproic acid

Description of Valproic acid

Valproic acid: anticonvulsant (trade name Depokene) used to prevent some kinds of seizures.
Source: WordNet 2.1

Valproic acid: A synthetic derivative of propylpentanoic acid with antiepileptic properties and potential antineoplastic and antiangiogenesis activities. In epilepsy, valproic acid appears to act by increasing the concentration of gamma-aminobutyric acid (GABA) in the brain. The antitumor and antiangiogenesis activities of this agent may be related to the inhibition of histone deacetylases and nitric oxide synthase, resulting in decreased production of nitric oxide. (NCI04)
Source: Diseases Database

Valproic acid: A fatty acid with anticonvulsant properties used in the treatment of epilepsy. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of voltage dependent sodium channels.
Source: MeSH 2007

Terms associated with Valproic acid:

Terms Similar to Valproic acid:

• Divalproex
• Valproate

Source: Diseases Database

• Depokene

Source - WordNet 2.1

• Dipropyl Acetate
• Divalproex
• Sodium Valproate

Source - MeSH 2007

Broader terms for Valproic acid

• Pentanoic Acids

Source - MeSH 2007

• anticonvulsant
• anticonvulsant drug
• antiepileptic
• antiepileptic drug

Source - WordNet 2.1

Hierarchical classifications of Valproic acid

The following list attempts to classify Valproic acid into categories where each line is subset of the next.

WordNet 2.1

• anticonvulsant,anticonvulsant drug,antiepileptic,antiepileptic drug
• medicament,medication,medicinal drug,medicine
• drug
• agent
• causal agency,causal agent,cause
• entity

Source: WordNet 2.1

MeSH 2007 Hierarchy:

• Organic Chemicals
  • Carboxylic Acids
    • Acids, Acyclic
      • Valerates
        • Pentanoic Acids
          • Valproic Acid

MeSH 2007 Hierarchy

• Lipids
  • Fatty Acids
    • Fatty Acids, Volatile
      • Valerates
        • Pentanoic Acids
          • Valproic Acid

External links related to: Valproic acid

• Search Jablonski's Syndromes Database
• Newly Approved Drug Therapies (133): Depakote (Divalproex Sodium), Abbott Laboratories
• Phenytoin versus valproate monotherapy for partial onset seizures and generalized onset tonic-clonic seizures (Cochrane Review)
• Convulex 500 mg Capsules , SPC from the eMC
• eMedicine - Toxicity, Valproate : Article by Timothy Wiegand, MD
• Depakote Online, Description, Chemistry, Ingredients - Divalproex Sodium - RxList Monographs
• Valproic Acid frame
• MDAdvice.com - Health Library - Prescription & Non-Prescription Drugs - DIVALPROEX
• Valproic acid (PIM 551)
• MedDet
• Valproic acid, valproate and divalproex in the maintenance treatment of bipolar disorder (Cochrane Review)
• Valproate for schizophrenia (Cochrane Review)
• Valproate preparations for agitation in dementia (Cochrane Review)
• Convulex 150 mg Capsules , SPC from the eMC
• Carbamazepine versus valproate monotherapy for epilepsy (Cochrane Review)
• Ethosuximide, sodium valproate or lamotrigine for absence seizures in children and adolescents (Cochrane Review)
• Convulex 300 mg Capsules , SPC from the eMC
• Depakote tablets , SPC from the eMC
• Valproic Acid
• Bipolar disorder - new drugs (No. 66)
• Valproate for acute mood episodes in bipolar disorder (Cochrane Review)
• Early versus late antiepileptic drug withdrawal for people with epilepsy in remission (Cochrane Review)
• Divalproex Sodium
• Depacon Online, Description, Chemistry, Ingredients - Valproate Sodium - RxList Monographs
• Depakene Online, Description, Chemistry, Ingredients - Valproic Acid - RxList Monographs

Source: Diseases Database

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