Causes of Neonatal myasthenia
Neonatal myasthenia Causes: Book Excerpts
Neonatal myasthenia as a complication of other conditions:
Other conditions that might have
Neonatal myasthenia as a complication may,
potentially, be an underlying cause of Neonatal myasthenia.
Our database lists the following as having
Neonatal myasthenia as a complication of that condition:
Related information on causes of Neonatal myasthenia:
As with all medical conditions,
there may be many causal factors.
Further relevant information on causes of Neonatal myasthenia may be found in:
Causes of Neonatal myasthenia: Online Medical Books
16 MEDICAL BOOKS ONLINE!
Review excerpts from medical books online, free, without registration,
for more information about the causes of Neonatal myasthenia.
Seizures – Neonatal:
Differential Diagnosis
(In A Page: Pediatric Signs and Symptoms)
-
Hypoxic ishemic encephalopathy
-
Bacterial meningitis/sepsis
-
Stroke
-
Cerebral dysgenesis
-
Electrolyte disturbances
–Hypoglycemia
–Hyponatremia
–Hypomagnesemia
–Hypocalcemia
-
Maternal drug use
–Drug withdrawal after delivery
–Direct effect of drugs, such as cocaine
-
Congenital infections (TORCH)
–Toxoplasmosis
–Syphilis
–Rubella
–CMV
–HSV - HSV encephalitis
-
Intracranial hemorrhage
–Subdural hemorrhage
–Intraparenchymal hemorrhage
–Intraventricular hemorrhage in the premature infant
–Subarachnoid hemorrhage
-
Urea cycle disturbances
-
Smith-Lemli-Opitz syndrome
-
Nonketotic hyperglycinemia
-
Pyridoxine deficiency
-
Fructose dysmetabolism
-
Amino acidurias
–Maple syrup urine disease
–Proprionic acidemia
-
Molybdenum cofactor deficiency
-
Mitochondrial encephalopathy
-
Glucose transporter deficiency
-
Benign etiologies
–Benign idiopathic neonatal seizures (fifth day fits)
–Benign familial neonatal seizures
-
Movements commonly mistaken for seizures
–Benign neonatal sleep myoclonus
–Jitteriness (may be secondary to
hypoglycemia, drug withdrawal, or
idiopathic)
–Gastroesophageal reflux (arching, writhing)
–Breath-holding spell
» READ BOOK EXCERPT ONLINE »
Source: In A Page: Pediatric Signs and Symptoms, 2007
Myasthenia gravis:
Causes and incidence
(Professional Guide to Diseases (Eighth Edition))
Myasthenia gravis causes a failure in transmission of nerve impulses at the neuromuscular junction. Theoretically, such impairment may result from an autoimmune response, ineffective acetylcholine release, or inadequate muscle fiber response to acetylcholine. (See Impaired transmission in myasthenia gravis.)
Myasthenia gravis affects 3 of every 10,000 people at any age, but it’s more common in young women and older men. About 20% of neonates born to mothers with myasthenia gravis have transient (or occasionally persistent) myasthenia. This disease may coexist with immunologic and thyroid disorders; about 15% of patients with myasthenia gravis have thymomas. Remissions occur in about 25% of patients.
» READ BOOK EXCERPT ONLINE »
Source: Professional Guide to Diseases (Eighth Edition), 2005
Myasthenia gravis:
Causes
(Handbook of Diseases)
Myasthenia gravis causes a failure in transmission of nerve impulses at the neuromuscular junction. Such impairment may result from an autoimmune response, ineffective acetylcholine release, or inadequate muscle fiber response to acetylcholine.
Myasthenia gravis affects 3 in 10,000 people at any age and is more common in young women and older men.
This disease may coexist with immune and thyroid disorders; about 15% of myasthenic patients have thymomas. Remissions occur in about 25% of patients.
gender influence Pregnancy is possible for female patients with myasthenia gravis, although they must be closely supervised. About 20% of infants born to myasthenic mothers have transient, or occasionally persistent myasthenia. The infant appears temporarily weak and may require medications for a few weeks after birth. Usually the baby doesn’t develop the disorder, but he must receive follow-up attention.
» READ BOOK EXCERPT ONLINE »
Source: Handbook of Diseases, 2003
Neonatal Apnea:
Neonatal Apnea - risk factors
(The 5-Minute Pediatric Consult)
- Prematurity
- Respiratory syncytial virus (RSV) infection
- Gastroesophageal reflux
- Sepsis
- Fluctuating incubator temperatures
- Large patent ductus arteriosus
- CNS insult, such as hemorrhage, hypoxia, or seizures
- Head flexion during holding or sleeping
- Maternal medications, such as magnesium sulfate, prostaglandins, or narcotics
- Following pertussis vaccine administration
Neonatal Apnea - pathophysiology
- Immature carbon dioxide chemoreceptors in the brainstem may be responsible for the decrease in respiratory drive.
- Hypercapnia leading to decreased muscle tone and incoordination of the upper airway muscles may result in mixed apnea.
- Activation of laryngeal afferent nerves, as with gastroesophageal reflux, may result in glottal closure.
- Vagally mediated responses to hypoventilation have been suggested as the cause of bradycardia.
» READ BOOK EXCERPT ONLINE »
Source: The 5-Minute Pediatric Consult, 2008
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