Causes of Neural tube defect
Causes of Neural tube defect (Diseases Database):
The follow list shows some of the possible medical causes of Neural tube defect
that are listed by the Diseases Database:
Source: Diseases Database
Neural tube defect Causes: Book Excerpts
Neural tube defect as a symptom:
Conditions listing Neural tube defect
as a symptom may also be potential underlying causes of Neural tube defect.
Our database lists the following as having
Neural tube defect as a symptom of that condition:
Medical news summaries relating to Neural tube defect:
The following medical news items are relevant to causes of Neural tube defect:
Related information on causes of Neural tube defect:
As with all medical conditions,
there may be many causal factors.
Further relevant information on causes of Neural tube defect may be found in:
Causes of Neural tube defect: Online Medical Books
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for more information about the causes of Neural tube defect.
Neural tube defects:
Causes and incidence
(Professional Guide to Diseases (Eighth Edition))
NTDs may be isolated birth defects, may result from exposure to a teratogen, or may be part of a multiple malformation syndrome (for example, chromosomal abnormalities such as trisomy 18 or 13 syndrome). Isolated NTDs (those not due to a specific teratogen or associated with other malformations) are believed to be caused by a combination of genetic and environmental factors. Although most of the specific environmental triggers are unknown, recent research has identified a lack of folic acid in the mother's diet as one of the risk factors.
The incidence of NTDs varies greatly among countries and by region in the United States. For example, the incidence is significantly higher in the British Isles and low in southern China and Japan. In the United States, North and South Carolina have at least twice the incidence of NTDs as most other parts of the country. These birth defects are also less common in blacks than in whites.
» READ BOOK EXCERPT ONLINE »
Source: Professional Guide to Diseases (Eighth Edition), 2005
Spinal cord defects:
Causes
(Handbook of Diseases)
Normally, about 20 days after conception, the embryo develops a neural groove in the dorsal ectoderm. This groove rapidly deepens, and the two edges fuse to form the neural tube.
By about day 23, this tube is completely closed except for an opening at each end. Theoretically, if the posterior portion of this neural tube fails to close by the 4th week of gestation, or if it closes but then splits open from a cause such as an abnormal increase in CSF later in the first trimester, a spinal defect results.
Viruses, radiation, and other environmental factors may be responsible for such defects. However, spinal cord defects occur more often in offspring of women who have previously had children with similar defects, so genetic factors may also be responsible.
» READ BOOK EXCERPT ONLINE »
Source: Handbook of Diseases, 2003
Neural tube defects:
Causes
(Handbook of Diseases)
NTDs may be isolated birth defects, may result from exposure to a teratogen, or may be part of a multiple malformation syndrome (for example, chromosomal abnormalities such as trisomy 18 or 13 syndrome). Isolated NTDs (those not due to a specific teratogen or associated with other malformations) are believed to be caused by a combination of genetic and environmental factors. Although most of the specific environmental triggers are unknown, recent research has identified a lack of folic acid in the mother’s diet as a risk factor.
The incidence of NTDs varies greatly among countries and by region in the United States. For example, the incidence is significantly higher in the British Isles and lower in southern China and Japan. In the United States, Appalachian and East Coast areas have a slightly higher incidence of NTDs than most other parts of the country. These birth defects are also more common in whites than in blacks.
» READ BOOK EXCERPT ONLINE »
Source: Handbook of Diseases, 2003
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