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Diseases » Neural tube defect » Prevalence
 

Prevalence and Incidence of Neural tube defect

Neural tube defect: Rare Disease

Neural tube defect is listed as a "rare disease" by the Office of Rare Diseases (ORD) of the National Institutes of Health (NIH). This means that Neural tube defect, or a subtype of Neural tube defect, affects less than 200,000 people in the US population.

Ophanet, who are a consortium of European partners, currently defines a condition rare when if affects 1 person per 2,000. They list Neural tube defect as a "rare disease". More information about Neural tube defect is available from Orphanet

Neural tube defect Prevalence: Book Excerpts

Incidence (annual) of Neural tube defect:

11.57 per 10,000 births with neural tube defects in the UK 2002 (University of Ulster, 2003) ... see also overview of Neural tube defect.

Incidence Rate:

approx 1 in 58,772 or 0.00% or 4,627 people in USA [Source statistic for calcuation: "11.57 per 10,000 births with neural tube defects in the UK 2002 (University of Ulster, 2003)" -- see also general information about data sources]

Incidence extrapolations for USA for Neural tube defect:

4,627 per year, 385 per month, 88 per week, 12 per day, 0 per hour, 0 per minute, 0 per second. [Source statistic for calculation: "11.57 per 10,000 births with neural tube defects in the UK 2002 (University of Ulster, 2003)" -- see also general information about data sources]

Incidence of types of Neural tube defect:

For details see incidence of types of Neural tube defect analysis; summary of available incidence by type data:

Incidence statistics for Neural tube defect:

The following statistics relate to the incidence of Neural tube defect:

  • 3 infants were born alive with neural tube defects in the UK 2002 (University of Ulster, 2003)
  • 5 fetal deaths or still births occurred due to neural tube defects in the UK 2002 (University of Ulster, 2003)
  • 37 cases of induced abortions occurred following prenatal diagnosis of neural tube defects in the UK 2002 (University of Ulster, 2003)
  • Neural tube defects occurred in 11.57 per 10,000 births in the UK 2002 (University of Ulster, 2003)
  • 0 infants were born alive with anencephalus and similar neural tube defects in the UK 2002 (University of Ulster, 2003)
  • 0 fetal deaths or still births occurred due to anencephalus and similar neural tube defects in the UK 2002 (University of Ulster, 2003)
  • 12 cases of induced abortions occurred following prenatal diagnosis of anencephalus and similar neural tube defects in the UK 2002 (University of Ulster, 2003)
  • Anencephalus and similar neural tube defects occurred in 4.08 per 10,000 births in the UK 2002 (University of Ulster, 2003)
  • more statistics...»

Prevalence/Incidence of Neural tube defect: Online Medical Books

16 MEDICAL BOOKS ONLINE! Review excerpts from medical books online, free, without registration, for more information about the prevalence and/or incidence of Neural tube defect.

Neural tube defects: Causes and incidence
(Professional Guide to Diseases (Eighth Edition))

NTDs may be isolated birth defects, may result from exposure to a teratogen, or may be part of a multiple malformation syndrome (for example, chromosomal abnormalities such as trisomy 18 or 13 syndrome). Isolated NTDs (those not due to a specific teratogen or associated with other malformations) are believed to be caused by a combination of genetic and environmental factors. Although most of the specific environmental triggers are unknown, recent research has identified a lack of folic acid in the mother's diet as one of the risk factors.

The incidence of NTDs varies greatly among countries and by region in the United States. For example, the incidence is significantly higher in the British Isles and low in southern China and Japan. In the United States, North and South Carolina have at least twice the incidence of NTDs as most other parts of the country. These birth defects are also less common in blacks than in whites.

» READ BOOK EXCERPT ONLINE »

Source: Professional Guide to Diseases (Eighth Edition), 2005

Neural Tube Defects: Neural Tube Defects - epidemiology
(The 5-Minute Pediatric Consult)

Neural Tube Defects - prevalence

  • 1 in 1,000 live births in the US (not including occult defects, for which no accurate epidemiologic data are available)
  • Anencephaly: 3.7 in 10,000
  • Encephalocele: 1.4 in 10,000
  • Spina bifida: 5.5 in 10,000
  • Myelomeningocele: 2–4 in 10,000

» READ BOOK EXCERPT ONLINE »

Source: The 5-Minute Pediatric Consult, 2008

About prevalence and incidence statistics:

The term 'prevalence' of Neural tube defect usually refers to the estimated population of people who are managing Neural tube defect at any given time. The term 'incidence' of Neural tube defect refers to the annual diagnosis rate, or the number of new cases of Neural tube defect diagnosed each year. Hence, these two statistics types can differ: a short-lived disease like flu can have high annual incidence but low prevalence, but a life-long disease like diabetes has a low annual incidence but high prevalence. For more information see about prevalence and incidence statistics.


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