Conditions listing Neurofibromatosis as a symptom may also be potential underlying causes of Neurofibromatosis. Our database lists the following as having Neurofibromatosis as a symptom of that condition:
Causes: Neurofibromatosis:
Although many affected persons inherit the disorder, between
30 and 50 percent of new cases arise spontaneously through mutation
(change) in an individual's genes.
(Source: excerpt from NINDS Neurofibromatosis Information Page: NINDS)
As with all medical conditions, there may be many causal factors. Further relevant information on causes of Neurofibromatosis may be found in:
16 MEDICAL BOOKS ONLINE! Review excerpts from medical books online, free, without registration, for more information about the causes of Neurofibromatosis.
NF-1 is an autosomal dominant disorder of chromosome 17 that occurs in about 1 in 3,000 births. Approximately 50% of affected families have a negative family history; in many of these families, the father is older, suggesting that advanced paternal age may influence the NF-1 mutation. NF-2 is an autosomal dominant disorder of chromosome 22; however, many patients have a negative family history.
Source: Professional Guide to Diseases (Eighth Edition), 2005
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