Neurofibromatosis is listed as a "rare disease" by the Office of Rare Diseases (ORD) of the National Institutes of Health (NIH). This means that Neurofibromatosis, or a subtype of Neurofibromatosis, affects less than 200,000 people in the US population.
Ophanet, who are a consortium of European partners, currently defines a condition rare when if affects 1 person per 2,000. They list Neurofibromatosis as a "rare disease". More information about Neurofibromatosis is available from Orphanet
about 1 in 30001. ... see also overview of Neurofibromatosis.
approx 1 in 3,000 or 0.03% or 90,666 people in USA [Source statistic for calcuation: "about 1 in 30001." -- see also general information about data sources]
90,666 per year, 7,555 per month, 1,743 per week, 248 per day, 10 per hour, 0 per minute, 0 per second. [Source statistic for calculation: "about 1 in 30001." -- see also general information about data sources]
The following statistics relate to the prevalence of Neurofibromatosis:
16 MEDICAL BOOKS ONLINE! Review excerpts from medical books online, free, without registration, for more information about the prevalence and/or incidence of Neurofibromatosis.
NF-1 is an autosomal dominant disorder of chromosome 17 that occurs in about 1 in 3,000 births. Approximately 50% of affected families have a negative family history; in many of these families, the father is older, suggesting that advanced paternal age may influence the NF-1 mutation. NF-2 is an autosomal dominant disorder of chromosome 22; however, many patients have a negative family history.
Source: Professional Guide to Diseases (Eighth Edition), 2005
Independent of sex, race, or environmental factors
1 in every 3,000–4,000 live births
NF1 affects 100,000 Americans.
Source: The 5-Minute Pediatric Consult, 2008
The term 'prevalence' of Neurofibromatosis usually refers to the estimated population
of people who are managing Neurofibromatosis at any given time.
The term 'incidence' of Neurofibromatosis refers to the annual diagnosis rate,
or the number of new cases of Neurofibromatosis diagnosed each year.
Hence, these two statistics types can differ:
a short-lived disease like flu can have high annual incidence but low prevalence,
but a life-long disease like diabetes has a low annual incidence but high prevalence.
For more information see about prevalence and incidence statistics.
Footnotes:
1. Pathophysiology of Disease, Stephen J. McPhee, Vishwanash R. Lingappa, Willim F. Ganong, Jack D. Lang, Prentice Hall, 1995
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