Neurofibromatosis-2: Neurofibromatosis, type 2, (NF-2) is a rare inherited disorder characterized by the development of benign tumors on both auditory nerves (acoustic neuromas). The ... more about Neurofibromatosis-2.
Neurofibromatosis-2: Genetic disorder often leading to tumors on nerves. More detailed information about the symptoms, causes, and treatments of Neurofibromatosis-2 is available below.
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Neurofibromatosis, type 2, (NF-2) is a rare inherited disorder characterized by the development of benign tumors on both auditory nerves (acoustic neuromas). The disease is also characterized by the development of malignant central nervous system tumors as well. (Source: Genes and Disease by the National Center for Biotechnology)
An autosomal dominant disorder characterized by a high incidence of bilateral acoustic neuromas as well as schwannomas (NEURILEMMOMA) of other cranial and peripheral nerves, and other benign intracranial tumors including meningiomas, ependymomas, spinal neurofibromas, and gliomas. The disease has been linked to mutations of the NF2 gene (GENES, NEUROFIBROMATOSIS 2) on chromosome 22 (22q12) and usually presents clinically in the first or second decade of life. - (Source - Diseases Database)
Neurofibromatosis-2 is listed as a "rare disease" by the Office of
Rare Diseases (ORD) of the National Institutes of Health
(NIH). This means that Neurofibromatosis-2, or a subtype of Neurofibromatosis-2,
affects less than 200,000 people in the US population.
Source - National Institutes of Health (NIH)
Ophanet, a consortium of European partners,
currently defines a condition rare when it affects 1 person per 2,000.
They list Neurofibromatosis-2 as a "rare disease".
Source - Orphanet
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