Neuroleptic Malignant Syndrome

Introduction: Neuroleptic Malignant Syndrome

Neuroleptic Malignant Syndrome: Neuroleptic malignant syndrome is a life-threatening, neurological disorder most often caused by an adverse reaction to neuroleptic or antipsychotic ... more about Neuroleptic Malignant Syndrome.

Neuroleptic Malignant Syndrome: A severe, potentially fatal reaction to antipsychotic drugs. More detailed information about the symptoms, causes, and treatments of Neuroleptic Malignant Syndrome is available below.

Symptoms of Neuroleptic Malignant Syndrome

• High fever
• Sweating
• Unstable blood pressure
• Stupor
• Muscular rigidity

See full list of 40 symptoms of Neuroleptic Malignant Syndrome

Wrongly Diagnosed with Neuroleptic Malignant Syndrome?

• Misdiagnosis of Neuroleptic Malignant Syndrome

Causes of Neuroleptic Malignant Syndrome

• Levomepromazine
• Haloperidol
• Thioridazine
• Trifluperidol
• Pipothiazine

See full list of 8 causes of Neuroleptic Malignant Syndrome

Read more about causes of Neuroleptic Malignant Syndrome.

More information about causes of Neuroleptic Malignant Syndrome:

• Medications, drugs, or substances causing Neuroleptic Malignant Syndrome (15 listings)
• Drug interactions causing Neuroleptic Malignant Syndrome (42 listings)

Treatments for Neuroleptic Malignant Syndrome

• Emergency intensive care
• Discontinue medications causing the reaction
• Fever treatments
• Muscle relaxant
• Dopaminergic drugs

See full list of 6 treatments for Neuroleptic Malignant Syndrome

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Prognosis for Neuroleptic Malignant Syndrome

Prognosis for Neuroleptic Malignant Syndrome: Early identification of and treatment for individuals with neuroleptic malignant syndrome improves outcome. (Source: excerpt from NINDS Neuroleptic Malignant Syndrome Information Page: NINDS)

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Article Excerpts about Neuroleptic Malignant Syndrome

Neuroleptic malignant syndrome is a life-threatening, neurological disorder most often caused by an adverse reaction to neuroleptic or antipsychotic drugs. (Source: excerpt from NINDS Neuroleptic Malignant Syndrome Information Page: NINDS)

Definitions of Neuroleptic Malignant Syndrome:

A potentially fatal syndrome associated primarily with the use of neuroleptic agents (see ANTIPSYCHOTIC AGENTS) which are in turn associated with dopaminergic receptor blockade (see RECEPTORS, DOPAMINE) in the BASAL GANGLIA and HYPOTHALAMUS, and sympathetic dysregulation. Clinical features include diffuse MUSCLE RIGIDITY; TREMOR; high FEVER; diaphoresis; labile blood pressure; cognitive dysfunction; and autonomic disturbances. Serum CPK level elevation and a leukocytosis may also be present. (From Adams et al., Principles of Neurology, 6th ed, p1199; Psychiatr Serv 1998 Sep;49(9):1163-72) - (Source - Diseases Database)