Peripheral Neuropathy

Peripheral Neuropathy: Excerpt from A Pocket Manual of Differential Diagnosis

Primary Motor, Acute (May Have Sensory Involvement)

Guillain-Barré syndrome
Infectious mononucleosis
Viral hepatitis
Porphyria
Diphtheria
Toxins (e.g., organophosphorous compounds, thallium, and vaccine for rabies, typhoid, smallpox)

Sensorimotor, Subacute

Alcoholism with associated nutritional deficiency
Beriberi
Other vitamin deficiencies (B₂, B₃, B₆, B₁₂, E)
Drugs, toxins
   Arsenic
   Mercury
   Thallium
   Lithium
   Gold
   Platinum
   Acrylamide
   Lead
   Industrial solvents
   Carbon monoxide
   Neuromuscular blockers (prolonged use)
   Nitrofurantoin
   Vincristine
   Hydralazine
   Metronidazole
   Phenytoin
   Isoniazid
   Ethionamide
   Disulfiram
   Cisplatin
   Amiodarone
   Thalidomide
   Taxol
   Suramin
   Chloramphenicol
   Pyroxidine
   Dapsone
   Doxorubicin
   Colchicine
   Chloroquine
   Nucleosides (ddC, ddI)
Diabetes mellitus
Atherosclerosis
Vasculitis (e.g., polyarteritis nodosa, systemic lupus erythematosus, Wegener's granulomatosis, rheumatoid arthritis)
Sarcoidosis
Subacute asymmetric idiopathic polyneuritis
Nonsystemic vasculitic neuropathy

Sensorimotor, Chronic

Carcinoma, lymphoma, leukemia
Amyloidosis
Paraproteinemia (especially multiple myeloma, macroglobulinemia, cryoglobulinemia)
Uremia
Beriberi
Alcoholism
Diabetes mellitus
Lyme disease
HIV infection
Ischemia
Critical illness neuropathy
Connective-tissue disease (especially systemic lupus
erythematosus)
Myxedema
Leprosy
Chronic inflammatory demyelinating polyradiculoneuropathy
Hereditary disease
   Charcot-Marie-Tooth disease
   Hereditary sensory and autonomic neuropathies
   Dejerine-Sottas disease
   Hereditary neuropathy with lability to pressure palsies
   Refsum's disease
   Abetalipoproteinemia and Tangier disease
   Metachromatic leukodystrophy
   Roussy-Lévy syndrome
   Fabry's disease
   Familial dysautonomia (Riley-Day syndrome)
   Familial amyloid neuropathies
   Ataxia telangiectasia
   Porphyric neuropathies

References

1. Adams, p. 1117. See Bibliography, 1.
2. Feosby TE: Disorders of the Peripheral Nervous System, p. 2441. See Bibliography, 3.

Book Source Details

• Book Title: A Pocket Manual of Differential Diagnosis
• Author(s): Stephen N. Adler, Dianne B. Gasbarra
• Year of Publication: 1999
• Copyright Details: A Pocket Manual of Differential Diagnosis, Copyright © 1999 Lippincott Williams & Wilkins.

More About Neuropathy

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• Next Book Extract About Neuropathy: Peripheral Neuropathy (Field Guide to Bedside Diagnosis)
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Copyright notice for book excerpts: Copyright © 2008 Lippincott Williams & Wilkins. All rights reserved.

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More About This Book: Title: A Pocket Manual of Differential Diagnosis Authors: Stephen N. Adler, Dianne B. Gasbarra Publisher: Lippincott Williams & Wilkins Copyright: 1999 ISBN: 0-78171-943-7

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