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Treatments for Non-Hodgkin's Lymphoma

Treatments for Non-Hodgkin's Lymphoma

The list of treatments mentioned in various sources for Non-Hodgkin's Lymphoma includes the following list. Always seek professional medical advice about any treatment or change in treatment plans.

Non-Hodgkin's Lymphoma: Is the Diagnosis Correct?

The first step in getting correct treatment is to get a correct diagnosis. Differential diagnosis list for Non-Hodgkin's Lymphoma may include:

Non-Hodgkin's Lymphoma: Marketplace Products, Discounts & Offers

Products, offers and promotion categories available for Non-Hodgkin's Lymphoma:

Non-Hodgkin's Lymphoma: Research Doctors & Specialists

Research all specialists including ratings, affiliations, and sanctions.

Drugs and Medications used to treat Non-Hodgkin's Lymphoma:

Note:You must always seek professional medical advice about any prescription drug, OTC drug, medication, treatment or change in treatment plans.

Some of the different medications used in the treatment of Non-Hodgkin's Lymphoma include:

Unlabeled Drugs and Medications to treat Non-Hodgkin's Lymphoma:

Unlabelled alternative drug treatments for Non-Hodgkin's Lymphoma include:

Latest treatments for Non-Hodgkin's Lymphoma:

The following are some of the latest treatments for Non-Hodgkin's Lymphoma:

Hospital statistics for Non-Hodgkin's Lymphoma:

These medical statistics relate to hospitals, hospitalization and Non-Hodgkin's Lymphoma:

  • 0.068% (8,683) of hospital consultant episodes were for follicular non-Hodgkin’s disease in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03)
  • 96% of hospital consultant episodes for required hospital admission in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03)
  • 54% of hospital consultant episodes for follicular non-Hodgkin’s disease were for men in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03)
  • 46% of hospital consultant episodes for follicular non-Hodgkin’s disease were for women in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03)
  • more hospital information...»

Hospitals & Medical Clinics: Non-Hodgkin's Lymphoma

Research quality ratings and patient incidents/safety measures for hospitals and medical facilities in specialties related to Non-Hodgkin's Lymphoma:

Hospital & Clinic quality ratings » »

Choosing the Best Treatment Hospital: More general information, not necessarily in relation to Non-Hodgkin's Lymphoma, on hospital and medical facility performance and surgical care quality:

Medical news summaries about treatments for Non-Hodgkin's Lymphoma:

The following medical news items are relevant to treatment of Non-Hodgkin's Lymphoma:

Discussion of treatments for Non-Hodgkin's Lymphoma:

What You Need To Know About Non-Hodgkin's Lymphoma: NCI (Excerpt)

Non-Hodgkin's lymphoma is usually treated with chemotherapy , radiation therapy , or a combination of these treatments. In some cases, bone marrow transplantation , biological therapies , or surgery may be options. For indolent lymphomas, the doctor may decide to wait until the disease causes symptoms before starting treatment. Often, this approach is called "watchful waiting." (Source: excerpt from What You Need To Know About Non-Hodgkin's Lymphoma: NCI)

What You Need To Know About Non-Hodgkin's Lymphoma: NCI (Excerpt)

Chemotherapy and radiation therapy are the most common treatments for non-Hodgkin's lymphoma, although bone marrow transplantation, biological therapies, or surgery are sometimes used.

Chemotherapy is the use of drugs to kill cancer cells. Chemotherapy for non-Hodgkin's lymphoma usually consists of a combination of several drugs. Patients may receive chemotherapy alone or in combination with radiation therapy.

Chemotherapy is usually given in cycles: a treatment period followed by a recovery period, then another treatment period, and so on. Most anticancer drugs are given by injection into a blood vessel (IV ); some are given by mouth. Chemotherapy is a systemic treatment because the drugs enter the bloodstream and travel throughout the body.

Usually a patient has chemotherapy as an outpatient (at the hospital, at the doctor's office, or at home). However, depending on which drugs are given and the patient's general health, a short hospital stay may be needed.

These are some questions patients may want to ask the doctor before starting chemotherapy:

  • What is the goal of this treatment?

  • What drugs will I be taking?

  • Will the drugs cause side effects? What can I do about them?

  • What side effects should I report to you?

  • How long will I need to take this treatment?

  • What can I do to take care of myself during treatment?

  • How will we know if the drugs are working?

Radiation therapy (also called radiotherapy) is the use of high-energy rays to kill cancer cells. Treatment with radiation may be given alone or with chemotherapy. Radiation therapy is local treatment ; it affects cancer cells only in the treated area. Radiation therapy for non-Hodgkin's lymphoma comes from a machine that aims the high-energy rays at a specific area of the body. There is no radioactivity in the body when the treatment is over.

These are some questions a patient may want to ask the doctor before having radiation therapy:

  • What is the goal of this treatment?

  • What are its risks and possible side effects?

  • What side effects should I report to you?

  • How will radiation be given?

  • When will the treatments begin? When will they end?

  • What can I do to take care of myself during therapy?

  • How will we know if the radiation therapy is working?

  • How will treatment affect my normal activities?

Sometimes patients are given chemotherapy and/or radiation therapy to kill undetected cancer cells that may be present in the central nervous system (CNS). In this treatment, called central nervous system prophylaxis , the doctor injects anticancer drugs directly into the cerebrospinal fluid .

Bone marrow transplantation (BMT) may also be a treatment option, especially for patients whose non-Hodgkin's lymphoma has recurred (come back). BMT provides the patient with healthy stem cells (very immature cells that produce blood cells) to replace cells damaged or destroyed by treatment with very high doses of chemotherapy and/or radiation therapy. The healthy bone marrow may come from a donor, or it may be marrow that was removed from the patient, treated to destroy cancer cells, stored, and then given back to the person following the high-dose treatment. Until the transplanted bone marrow begins to produce enough white blood cells, patients have to be carefully protected from infection. They usually stay in the hospital for several weeks.

These are some questions patients may want to ask the doctor before having a BMT:

  • What are the benefits of this treatment?

  • What are the risks and possible side effects? What can be done about them?

  • What side effects should I report to you?

  • How long will I be in the hospital? What care will I need after I leave the hospital?

  • How will the treatment affect my normal activities?

  • How will I know if the treatment is working?

Biological therapy (also called immunotherapy) is a form of treatment that uses the body's immune system, either directly or indirectly, to fight cancer or to lessen the side effects that can be caused by some cancer treatments. It uses materials made by the body or made in a laboratory to boost, direct, or restore the body's natural defenses against disease. Biological therapy is sometimes also called biological response modifier therapy.

These are some questions patients may want to ask the doctor before starting biological therapy:

  • What is the goal of this treatment?

  • What drugs will I be taking?

  • Will the treatment cause side effects? If so, what can I do about them?

  • What side effects should I report to you?

  • Will I have to be in the hospital to receive treatment?

  • How long will I need to take this treatment?

  • When will I be able to resume my normal activities?

Surgery may be performed to remove a tumor. Tissue around the tumor and nearby lymph nodes may also be removed during the operation. (Source: excerpt from What You Need To Know About Non-Hodgkin's Lymphoma: NCI)

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Book Excerpts: Treatment of Non-Hodgkin's Lymphoma

Treatments of Non-Hodgkin's Lymphoma: Online Medical Books

16 MEDICAL BOOKS ONLINE! Review excerpts from medical books online, free, without registration, for more information about the treatments of Non-Hodgkin's Lymphoma.

Lymphadenopathy: Treatment
(In a Page: Signs and Symptoms)

  • Viral infections require supportive therapy in most cases
  • Bacterial, parasitic, and fungal infections are usually treated with appropriate antibiotics, antiparasitics or antifungals, respectively
  • Offending medication should be removed when possible
  • Malignancies must be identified, staged, and treated as appropriate with chemotherapy, radiation, and/or resection as per the established oncology protocol

» READ BOOK EXCERPT ONLINE »

Source: In a Page: Signs and Symptoms, 2004

Lymphadenopathy: Treatment
(In A Page: Pediatric Signs and Symptoms)

    • Mild adenopathy with associated viral/URI symptoms
      –Observation and recheck in 1–2 weeks
      –Malignancy-associated adenopathy can sometimes wax and wane (especially Hodgkin disease) and appear to improve with antibiotics
      –TB nodes may be firm, matted, fixed, and nontender
  • Erythematous, warm, tender nodes
    –Trial of oral antibiotics for staph/strep
  • Inflamed/fluctuant lesions: Referral for I&D
    • Refer to pediatric hematologist/oncologist
      –Nodes that fail to resolve over 6 weeks
      –Nodes that increase in size over 2 weeks
      –Firm, matted nodes
      –Supraclavicular nodes
      –Nodes that generalize to two or more noncontiguous groups or more than two contiguous groups
  • CBC with differential, CXR before biopsy

» READ BOOK EXCERPT ONLINE »

Source: In A Page: Pediatric Signs and Symptoms, 2007

Non-Hodgkin's lymphoma: Treatment
(Professional Guide to Diseases (Eighth Edition))

Radiation therapy is used mainly in the early localized stage of the disease. Total nodal irradiation is generally effective for both nodular and diffuse histologies.

Chemotherapy is most effective with multiple combinations of antineoplastic agents. For example, cyclophosphamide, vincristine, Adriamycin, and prednisone can induce a complete remission in 70% to 80% of patients with nodular histology and in 20% to 55% of patients with diffuse histology. Other combinationssuch as methotrexate, bleomycin, Adriamycin, Cytoxan, Oncovin, and prednisone (M-BACOP)induce prolonged remission and sometimes cure the diffuse form.

In recent years, the development of monoclonal antibodies, specifically rituximab, has provided additional options for the treatment of non-Hodgkin's lymphomas either alone or in combination with traditional chemotherapy regimens. Additionally, radioimmunotherapy for the treatment of these lymphomas has shown promise. Monoclonal antibodies are labeled with beta-emitting isotopes. Currently, ibritumomab tiuxetan is being used alone and in combination with rituximab.

» READ BOOK EXCERPT ONLINE »

Source: Professional Guide to Diseases (Eighth Edition), 2005

Hodgkin's disease: Treatment
(Professional Guide to Diseases (Eighth Edition))

Appropriate therapy (chemotherapy or radiation, or both, varying with the stage of the disease) depends on careful physical examination with accurate histologic interpretation and proper clinical staging. (See Staging Hodgkin's disease.) Correct and timely treatment allows longer survival and even induces an apparent cure in many patients. Radiation therapy is used alone for stages I and II and in combination with chemotherapy for stage III. Chemotherapy is used for stage IV, sometimes inducing a complete remission. The well-known MOPP protocol (mechlorethamine, vincristine [Oncovin], procarbazine, and prednisone) was the first to provide significant cures to patients with generalized Hodgkin's; another useful combination is ABVD (doxorubicin [Adriamycin], bleomycin, vinblastine, and dacarbazine). Another chemotherapy regimen bleomycin, etoposide, cyclophosphamide, vincristine, procarbazine, and prednisonehas also shown promise in advanced Hodgkin's disease. Treatment with these drugs may require concomitant antiemetics, sedatives, or antidiarrheals to combat GI adverse effects.

New treatments include high-dose chemotherapeutic agents with autologous bone marrow transplantation or autologous peripheral blood stem cell transfusions. Biotherapy alone hasn't proven effective.

» READ BOOK EXCERPT ONLINE »

Source: Professional Guide to Diseases (Eighth Edition), 2005

Lymphomas, malignant: Treatment
(Handbook of Diseases)

Radiation therapy is used mainly in the early localized stage of the disease. Total nodal irradiation is usually effective for nodular and diffuse histologies.

Chemotherapy is most effective with multiple combinations of antineoplastics; remissions and cures may be induced in this manner. Some cases have required intrathecal chemotherapy. Bone marrow and stem cell transplants have also proved helpful.

» READ BOOK EXCERPT ONLINE »

Source: Handbook of Diseases, 2003

Hodgkin's disease: Treatment
(Handbook of Diseases)

Appropriate therapy (chemotherapy, radiation therapy, or both, depending on the stage of the disease) is based on a careful physical examination with accurate histologic interpretation and proper clinical staging. Correct and timely treatment allows longer survival and even induces an apparent cure in many patients.

Chemotherapy and radiation therapy

Radiation therapy is used alone for stage I and stage II and in combination with chemotherapy for stage III. Chemotherapy, usually in combinations, is used for stage IV, sometimes inducing a complete remission.

These treatments may require concomitant antiemetics, sedatives, or antidiarrheals to combat GI adverse effects.

Other treatments

Treatments include high-dose chemotherapeutic agents with autologous bone marrow transplantation or autologous peripheral blood stem cell transfusions. Biotherapy alone hasn’t proven effective.

» READ BOOK EXCERPT ONLINE »

Source: Handbook of Diseases, 2003

Lymphadenopathy: Patient counseling
(Signs & Symptoms: A 2-in-1 Reference for Nurses)

Explain the importance of avoiding crowds and washing hands properly to prevent infection. Teach the patient the signs and symptoms of infection he needs to report to the health care provider. If isolation is required, explain its purpose and associated interventions to the patient and his family. Encourage the patient to eat a healthy diet and get plenty of rest.

» READ BOOK EXCERPT ONLINE »

Source: Signs & Symptoms: A 2-in-1 Reference for Nurses, 2007

Lymphadenopathy: Nursing considerations
(Nursing: Interpreting Signs and Symptoms)

▪ If the patient is uncomfortable, provide an antipyretic, tepid sponge bath, or a hypothermia blanket.

▪ Expect to obtain blood for routine blood work, platelet and white blood cell counts, liver and renal function studies, erythrocyte sedimentation rate, and blood cultures.

▪ Prepare the patient for other diagnostic tests, such as chest X-ray, computed tomography, liver and spleen scan, lymph node biopsy, or lymphography, to visualize the lymphatic system.

▪ If tests reveal infection, check your facility's policy regarding infection control and isolation precautions.

Patient teaching

▪ Explain to the patient all diagnostic tests or procedures.

▪ Teach the patient ways to prevent infection.

▪ Explain the signs and symptoms of infection the patient should report.

▪ Explain the reasons for any isolation precautions.

▪ Stress the importance of a healthy diet and rest.

» READ BOOK EXCERPT ONLINE »

Source: Nursing: Interpreting Signs and Symptoms, 2007



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