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Causes of Obesity
List of causes of Obesity
Following is a list of causes or underlying conditions (see also Misdiagnosis of underlying causes of Obesity) that could possibly cause Obesity includes:
- Overeating - see causes of overeating
- Physical disorders that may cause or exacerbate obesity include:
- Metabolic syndrome
- Hypothyroidism
- Familial obesity
- Cushing's disease
- Cushing's syndrome
- PCOS
- Edema
- Insulinoma
- Pseudohypoparathyroidism
- Prader-Willi syndrome
- Laurence-Moon-Biedl syndrome
- Hypothalamus tumor
- Reactive hypoglycemia (type of Hypoglycemia) - overeating occurs to avoid going "down" into a hypoglycemic attack.
- See also causes of weight gain, causes of overeating or causes of fluid retention
- Psychological causes of obesity may include:
- Comfort eating (see Overeating)
- Overeating
- See also causes of weight gain
- Brain disorder causing increased eating (hyperphagia) include:
- Encephalitis
- Brain injury
- Third ventricle tumor
- Some brain tumors
- Chromophobe adenoma
- Craniopharyngioma (type of Brain cancer)
More causes: see full list of causes for Obesity
Causes of Obesity (Diseases Database):
The follow list shows some of the possible medical causes of Obesity that are listed by the Diseases Database:
- Cushing's disease
- Ethanol
- Cushing's syndrome
- Cohen syndrome
- Prader-Willi syndrome
- Melanocortin 4 receptor defect
- Kleine-Levin-Critchley syndrome
- Adiposogenital dystrophy
- Prednisolone
- Polyphagia
- Young-Hughes syndrome
- Hypothyroidism
- Laron dwarfism
- X-linked mental retardation-hypotonic facies syndrome
- Borjeson-Forssman-Lehmann syndrome
- Pseudohypoparathyroidism type 1a
- Pituitary tumour (growth hormone secreting)
- Insulinoma
- Bardet-Biedl syndrome
Causes of Obesity: Online Medical Books
16 MEDICAL BOOKS ONLINE! Review excerpts from medical books online, free, without registration, for more information about the causes of Obesity.
Obesity:
Differential Diagnosis
(In A Page: Pediatric Signs and Symptoms)
- Exogenous obesity (most common)
–No demonstrable disease as the cause
–Excessive weight gain from imbalance between caloric intake and energy expenditure
–Linear growth is robust and frequently accelerated
- Hormonal causes
–Associated with poor linear growth
–Hypercortisolism: Cushing syndrome is any type of glucocorticoid excess (endogenous or exogenous); Cushing disease describes pituitary ACTH overproduction
–Hypothyroidism
–Growth hormone deficiency
- Insulinoma
-
Hypothalamic obesity
–Tumors (e.g., craniopharyngiomas)
–Following neurosurgery or irradiation
–Head trauma
–Infiltrative/inflammatory -
Genetic syndromes
–Prader-Willi syndrome
–Laurence-Moon-Bardet-Biedl syndrome
–Alström syndrome
–Cohen syndrome
–Down syndrome
–Carpenter syndrome
–Grebe syndrome
–Beckwith-Wiedemann syndrome -
Defects in metabolic/eating regulatory pathways is an area of intense investigation; multiple mutations are theoretically possible, but only a few have actually been discovered in humans
–Congenital leptin deficiency (extremely rare)
–Leptin resistance (more common than deficiency) -
Drugs
–Chronic glucocorticoids
–Neuropsychotropic medications - Adiposogenital dystrophy syndrome
Abdominal distention:
Medical causes
(Handbook of Signs & Symptoms (Third Edition))
❑ Abdominal cancer.Generalized abdominal distention may occur when the cancer — most commonly ovarian, hepatic, or pancreatic — produces ascites (usually in a patient with a known tumor). It’s an indication of advanced disease. Shifting dullness and a fluid wave accompany distention. Associated signs and symptoms may include severe abdominal pain, an abdominal mass, anorexia, jaundice, GI hemorrhage (hematemesis or melena), dyspepsia, and weight loss that progresses to muscle weakness and atrophy.
❑ Abdominal trauma.When brisk internal bleeding accompanies trauma, abdominal distention may be acute and dramatic. Associated signs and symptoms of this life-threatening disorder include abdominal rigidity with guarding, decreased or absent bowel sounds, vomiting, tenderness, and abdominal bruising. Pain may occur over the trauma site, or over the scapula if abdominal bleeding irritates the phrenic nerve. Signs of hypovolemic shock (such as hypotension and rapid, thready pulse) appear with significant blood loss.
❑ Cirrhosis. In cirrhosis, ascites causes generalized distention and is confirmed by a fluid wave, shifting dullness, and a puddle sign. Umbilical eversion and caput medusae (dilated veins around the umbilicus) are common. The patient may report a feeling of fullness or weight gain. Associated findings include vague abdominal pain, fever, anorexia, nausea, vomiting, constipation or diarrhea, bleeding tendencies, severe pruritus, palmar erythema, spider angiomas, leg edema, and possibly splenomegaly. Hematemesis, encephalopathy, gynecomastia, or testicular atrophy may also be seen. Jaundice is usually a late sign. Hepatomegaly occurs initially, but the liver may not be palpable if the patient has advanced disease.
❑ Heart failure. Generalized abdominal distention due to ascites typically accompanies severe cardiovascular impairment and is confirmed by shifting dullness and a fluid wave. Signs and symptoms of heart failure are numerous and depend on the disease stage and degree of cardiovascular impairment. Hallmarks include peripheral edema, jugular vein distention, dyspnea, and tachycardia. Common associated signs and symptoms include hepatomegaly (which may cause right upper quadrant pain), nausea, vomiting, a productive cough, crackles, cool extremities, cyanotic nail beds, nocturia, exercise intolerance, nocturnal wheezing, diastolic hypertension, and cardiomegaly.
❑ Irritable bowel syndrome. Irritable bowel syndrome may produce intermittent, localized distention — the result of periodic intestinal spasms. Lower abdominal pain or cramping typically accompanies these spasms. The pain is usually relieved by defecation or by passage of intestinal gas and is aggravated by stress. Other possible signs and symptoms include diarrhea that may alternate with constipation or normal bowel function, nausea, dyspepsia, straining and urgency at defecation, a feeling of incomplete evacuation, and small, mucus-streaked stools.
❑ Large-bowel obstruction. Dramatic abdominal distention is characteristic in this life-threatening disorder; in fact, loops of the large bowel may become visible on the abdomen. Constipation precedes distention and may be the only symptom for days. Associated findings include tympany, high-pitched bowel sounds, and the sudden onset of colicky lower abdominal pain that becomes persistent. Fecal vomiting and diminished peristaltic waves and bowel sounds are late signs.
❑ Mesenteric artery occlusion (acute). In this life-threatening disorder, abdominal distention usually occurs several hours after the sudden onset of severe, colicky periumbilical pain accompanied by rapid (even forceful) bowel evacuation. The pain later becomes constant and diffuse. Related signs and symptoms include severe abdominal tenderness with guarding and rigidity, absent bowel sounds and, occasionally, a bruit in the right iliac fossa. The patient may also experience vomiting, anorexia, diarrhea, or constipation. Late signs include fever, tachycardia, tachypnea, hypotension, and cool, clammy skin. Abdominal distention or GI bleeding may be the only clue if pain is absent.
❑ Paralytic ileus. Paralytic ileus, which produces generalized distention with a tympanic percussion note, is accompanied by absent or hypoactive bowel sounds and, occasionally, mild abdominal pain and vomiting. The patient may be severely constipated or may pass flatus and small, liquid stools.
❑ Peritonitis. Peritonitis is a life-threatening disorder in which abdominal distention may be localized or generalized, depending on the extent of the inflammation. Fluid accumulates within the peritoneal cavity and then within the bowel lumen, causing a fluid wave and shifting dullness. Typically, distention is accompanied by sudden and severe abdominal pain that worsens with movement, rebound tenderness, and abdominal rigidity.
The skin over the patient’s abdomen may appear taut. Associated signs and symptoms usually include hypoactive or absent bowel sounds, fever, chills, hyperalgesia, nausea, and vomiting. Signs of shock, such as tachycardia and hypotension, appear with significant fluid loss into the abdomen.
❑ Small-bowel obstruction. Abdominal distention is characteristic in small-bowel obstruction, a life-threatening disorder, and is most pronounced during late obstruction, especially in the distal small bowel. Auscultation reveals hypoactive or hyperactive bowel sounds, whereas percussion produces a tympanic note. Accompanying signs and symptoms include colicky periumbilical pain, constipation, nausea, and vomiting; the higher the obstruction, the earlier and more severe the vomiting. Rebound tenderness reflects intestinal strangulation with ischemia. Associated signs and symptoms include drowsiness, malaise, and signs of dehydration. Signs of hypovolemic shock appear with progressive dehydration and plasma loss.
❑ Toxic megacolon (acute).Toxic megacolon is a life-threatening complication of infectious or ulcerative colitis. It produces dramatic abdominal distention that usually develops gradually and is accompanied by a tympanic percussion note, diminished or absent bowel sounds, and mild rebound tenderness. The patient also presents with abdominal pain and tenderness, fever, tachycardia, and dehydration.
Obesity:
Causes and incidence
(Professional Guide to Diseases (Eighth Edition))
Obesity results from excessive calorie intake and inadequate expenditure of energy. Theories to explain this condition include hypothalamic dysfunction of hunger and satiety centers, genetic predisposition, abnormal absorption of nutrients, and impaired action of GI and growth hormones and of hormonal regulators such as insulin. An inverse relationship between socioeconomic status and the prevalence of obesity has been documented, especially in women. Obesity in parents increases the probability of obesity in children, from genetic or environmental factors, such as activity levels and learned patterns of eating. Psychological factors, such as stress or emotional eating, may also contribute to obesity. Rates of obesity are climbing, and the percentage of children and adolescents who are obese has doubled in the last 20 years.
Abdominal distention:
Medical causes
(Professional Guide to Signs & Symptoms (Fifth Edition))
Abdominal cancer
Generalized abdominal distention may occur when the cancer—most commonly ovarian, hepatic, or pancreatic cancer—produces ascites (usually in a patient with a known tumor). It’s an indication of advanced disease. Shifting dullness and a fluid wave accompany distention. Associated signs and symptoms may include severe abdominal pain, an abdominal mass, anorexia, jaundice, GI hemorrhage (hematemesis or melena), dyspepsia, and weight loss that progresses to muscle weakness and atrophy.
Abdominal trauma
When brisk internal bleeding accompanies trauma, abdominal distention may be acute and dramatic. Associated signs and symptoms of this life-threatening disorder include abdominal rigidity with guarding, decreased or absent bowel sounds, vomiting, tenderness, and abdominal bruising. The patient may feel pain over the trauma site, or over the scapula if abdominal bleeding irritates the phrenic nerve. Signs of hypovolemic shock (such as hypotension and rapid, thready pulse) appear with significant blood loss.
Bladder distention
Various disorders cause bladder distention, which in turn causes lower abdominal distention. Slight dullness on percussion above the symphysis indicates mild bladder distention. A palpable, smooth, rounded, fluctuant suprapubic mass suggests severe distention; a fluctuant mass extending to the umbilicus indicates extremely severe distention. Urinary dribbling, frequency, or urgency may occur with urinary obstruction. Suprapubic discomfort is also common.
Cirrhosis
In cirrhosis, ascites causes generalized distention and is confirmed by a fluid wave, shifting dullness, and a puddle sign. Umbilical eversion and caput medusae (dilated veins around the umbilicus) are common. The patient may report a feeling of fullness or weight gain. Associated findings include vague abdominal pain, fever, anorexia, nausea, vomiting, constipation or diarrhea, bleeding tendencies, severe pruritus, palmar erythema, spider angiomas, leg edema, and possibly splenomegaly. Hematemesis, encephalopathy, gynecomastia, or testicular atrophy may also occur. Jaundice is usually a late sign. Hepatomegaly occurs initially, but the liver may not be palpable in advanced disease.
Gastric dilation (acute)
Left-upper-quadrant distention is characteristic in acute gastric dilation, but the presentation varies. The patient usually complains of epigastric fullness or pain and nausea with or without vomiting. Physical examination reveals tympany, gastric tenderness, and a succussion splash. Initially, peristalsis may be visible. Later, hypoactive or absent bowel sounds confirm ileus. The patient may be pale and diaphoretic and may exhibit tachycardia or bradycardia.
Heart failure
Generalized abdominal distention due to ascites typically accompanies severe cardiovascular impairment and is confirmed by shifting dullness and a fluid wave. Signs and symptoms of heart failure are numerous and depend on the disease stage and degree of cardiovascular impairment. Hallmarks include peripheral edema, jugular vein distention, dyspnea, and tachycardia. Common associated signs and symptoms include hepatomegaly (which may cause right-upper-quadrant pain), nausea, vomiting, productive cough, crackles, cool extremities, cyanotic nail beds, nocturia, exercise intolerance, nocturnal wheezing, diastolic hypertension, and cardiomegaly.
Irritable bowel syndrome (IBS)
IBS may produce intermittent, localized distention—the result of periodic intestinal spasms. Lower abdominal pain or cramping typically accompanies these spasms. The pain is usually relieved by defecation or by passage of intestinal gas and is aggravated by stress. Other possible signs and symptoms include diarrhea that may alternate with constipation or normal bowel function; nausea; dyspepsia; straining and urgency at defecation; feeling of incomplete evacuation; and small, mucus-streaked stools.
Large-bowel obstruction
Dramatic abdominal distention is characteristic in large-bowel obstruction, a life-threatening disorder; in fact, loops of the large bowel may become visible on the abdomen. Constipation precedes distention and may be the only symptom for days. Associated findings include tympany, high-pitched bowel sounds, and sudden onset of colicky lower abdominal pain that becomes persistent. Fecal vomiting and diminished peristaltic waves and bowel sounds are late signs.
Mesenteric artery occlusion (acute)
In mesenteric artery occlusion—a life-threatening disorder—abdominal distention usually occurs several hours after the sudden onset of severe, colicky periumbilical pain accompanied by rapid (even forceful) bowel evacuation. The pain later becomes constant and diffuse. Related signs and symptoms include severe abdominal tenderness with guarding and rigidity, absent bowel sounds and, occasionally, a bruit in the right iliac fossa. The patient may also experience vomiting, anorexia, diarrhea, or constipation. Late signs include fever, tachycardia, tachypnea, hypotension, and cool, clammy skin. Abdominal distention or GI bleeding may be the only clue if pain is absent.
Nephrotic syndrome
Nephrotic syndrome may produce massive edema, causing generalized abdominal distention with a fluid wave and shifting dullness. It may also produce elevated blood pressure, hematuria or oliguria, fatigue, anorexia, depression, pallor, periorbital edema, scrotal swelling, and skin striae.
Ovarian cysts
Typically, large ovarian cysts produce lower abdominal distention accompanied by umbilical eversion. Because they’re thin walled and fluid filled, these cysts produce a fluid wave and shifting dullness—signs that mimic ascites. Lower abdominal pain and a palpable mass may be present.
Paralytic ileus
Paralytic ileus, which produces generalized distention with a tympanic percussion note, is accompanied by absent or hypoactive bowel sounds and, occasionally, mild abdominal pain and vomiting. The patient may be severely constipated or may pass flatus and small, liquid stools.
Peritonitis
In peritonitis—a life-threatening disorder—abdominal distention may be localized or generalized, depending on the extent of peritonitis. Fluid accumulates first within the peritoneal cavity and then within the bowel lumen, causing a fluid wave and shifting dullness. Typically, distention is accompanied by rebound tenderness, abdominal rigidity, and sudden and severe abdominal pain that worsens with movement.
The skin over the patient’s abdomen may appear taut. Associated signs and symptoms usually include hypoactive or absent bowel sounds, fever, chills, hyperalgesia, nausea, and vomiting. Signs of shock, such as tachycardia and hypotension, appear with significant fluid loss into the abdomen.
Small-bowel obstruction
Abdominal distention, which is characteristic in small-bowel obstruction—a life-threatening disorder—is most pronounced during late obstruction, especially in the distal small bowel. Auscultation reveals hypoactive or hyperactive bowel sounds, whereas percussion produces a tympanic note. Accompanying signs and symptoms include colicky periumbilical pain, constipation, nausea, and vomiting; the higher the obstruction, the earlier and more severe the vomiting. Rebound tenderness reflects intestinal strangulation with ischemia. Associated signs and symptoms include drowsiness, malaise, and signs of dehydration. Signs of hypovolemic shock appear with progressive dehydration and plasma loss.
Toxic megacolon (acute)
Toxic megacolon is a life-threatening complication of infectious or ulcerative colitis that produces dramatic abdominal distention. The distention usually develops gradually and is accompanied by a tympanic percussion note, diminished or absent bowel sounds, and mild rebound tenderness. The patient also experiences abdominal pain and tenderness, fever, tachycardia, and dehydration.
Obesity:
Differential Overview
(Field Guide to Bedside Diagnosis)
❑ Caloric excess
❑ Depression
❑ Drugs
❑ Hypothyroidism
❑ Hypogonadism
❑ Cushing syndrome
❑ Polycystic ovary syndrome
❑ Hypothalamic
❑ Insulinoma
Abdominal distention:
Medical causes
(Signs & Symptoms: A 2-in-1 Reference for Nurses)
Abdominal cancer
Generalized abdominal distention may occur when the cancer — most commonly ovarian, hepatic, or pancreatic — produces ascites (usually in a patient with a known tumor). It’s an indication of advanced disease. Shifting dullness and a fluid wave accompany distention. Associated signs and symptoms may include severe abdominal pain, an abdominal mass, anorexia, jaundice, GI hemorrhage (hematemesis or melena), dyspepsia, and weight loss that progresses to muscle weakness and atrophy.
Abdominal trauma
When brisk internal bleeding accompanies trauma, abdominal distention may be acute and dramatic. Associated signs and symptoms of this life-threatening disorder include abdominal rigidity with guarding, decreased or absent bowel sounds, vomiting, tenderness, and abdominal bruising. Pain may occur over the trauma site or over the scapula if abdominal bleeding irritates the phrenic nerve. Signs of hypovolemic shock (such as hypotension and rapid, thready pulse) appear with significant blood loss.
Bladder distention
Various disorders cause bladder distention which, in turn, causes lower abdominal distention. Slight dullness on percussion above the symphysis pubis indicates mild bladder distention. A palpable, smooth, rounded, fluctuant suprapubic mass suggests severe bladder distention; a fluctuant mass extending to the umbilicus indicates extremely severe bladder distention. Urinary dribbling, frequency, or urgency may occur with urinary obstruction. Suprapubic discomfort is also common.
Cirrhosis
With cirrhosis, ascites causes generalized distention and is confirmed by a fluid wave and shifting dullness. Umbilical eversion and caput medusae (dilated veins around the umbilicus) are common. The patient may report a feeling of fullness or weight gain. Associated findings include vague abdominal pain, fever, anorexia, nausea, vomiting, constipation or diarrhea, bleeding tendencies, severe pruritus, palmar erythema, spider angiomas, leg edema and, possibly, splenomegaly. Hematemesis, encephalopathy, gynecomastia, or testicular atrophy may also be seen. Jaundice is usually a late sign. Hepatomegaly occurs initially; however, the liver may not be palpable if the patient has advanced disease.
Gastric dilation (acute)
Left-upper-quadrant distention is characteristic of acute gastric dilation, but the presentation varies. The patient usually complains of epigastric fullness or pain and nausea (with or without vomiting). Physical examination reveals tympany, gastric tenderness, and a succussion splash. Initially, visible peristalsis may occur. Later, hypoactive or absent bowel sounds confirm ileus. The patient may be pale and diaphoretic and may exhibit tachycardia or bradycardia.
Heart failure
Generalized abdominal distention due to ascites typically accompanies severe cardiovascular impairment and is confirmed by shifting dullness and a fluid wave. Signs and symptoms of heart failure are numerous and depend on the disease stage and degree of cardiovascular impairment. Hallmarks include peripheral edema, jugular vein distention, dyspnea, and tachycardia. Common associated signs and symptoms include hepatomegaly (which may cause right-upper-quadrant pain), nausea, vomiting, productive cough, crackles, cool extremities, cyanotic nail beds, nocturia, exercise intolerance, nocturnal wheezing, diastolic hypertension, and cardiomegaly.
Irritable bowel syndrome
Irritable bowel syndrome may produce intermittent, localized distention — the result of periodic intestinal spasms. Lower abdominal pain or cramping typically accompanies these spasms. The pain is usually relieved by defecation or by passage of intestinal gas and is aggravated by stress. Other possible signs and symptoms include diarrhea that may alternate with constipation or normal bowel function; nausea; dyspepsia; straining and urgency at defecation; feeling of incomplete evacuation; and small, mucus-streaked stools.
Large-bowel obstruction
Dramatic abdominal distention is characteristic of large-bowel obstruction, a life-threatening disorder; in fact, loops of the large bowel may become visible on the abdomen. Constipation precedes distention and may be the only symptom for days. Associated findings include tympany, high-pitched bowel sounds, and the sudden onset of colicky lower abdominal pain that becomes persistent. Fecal vomiting and diminished peristaltic waves and bowel sounds are late signs.
Mesenteric artery occlusion (acute)
In acute mesenteric artery occlusion, a life-threatening disorder, abdominal distention usually occurs several hours after the sudden onset of severe, colicky periumbilical pain accompanied by rapid (even forceful) bowel evacuation. The pain later becomes constant and diffuse. Related signs and symptoms include severe abdominal tenderness with guarding and rigidity, absent bowel sounds and, occasionally, a bruit in the right iliac fossa. The patient may also experience vomiting, anorexia, diarrhea, or constipation. Late signs include fever, tachycardia, tachypnea, hypotension, and cool, clammy skin. Abdominal distention or GI bleeding may be the only clue if pain is absent.
Nephrotic syndrome
Nephrotic syndrome may produce massive edema, causing generalized abdominal distention with a fluid wave and shifting dullness. It may also produce elevated blood pressure, hematuria or oliguria, fatigue, anorexia, depression, pallor, periorbital edema, scrotal swelling, and skin striae.
Ovarian cysts
Typically, large ovarian cysts produce lower abdominal distention accompanied by umbilical eversion. Because they’re thin walled and fluid filled, these cysts produce a fluid wave and shifting dullness — signs that mimic ascites. Lower abdominal pain and a palpable mass may be present.
Paralytic ileus
Paralytic ileus, which produces generalized distention with a tympanic percussion note, is accompanied by absent or hypoactive bowel sounds and, occasionally, extreme distress and vomiting. The patient may be severely constipated or may pass flatus and small, liquid stools.
Peritonitis
In peritonitis, a life-threatening disorder, abdominal distention may be localized or generalized, depending on the extent of peritonitis. Fluid accumulates first within the peritoneal cavity and then within the bowel lumen, causing a fluid wave and shifting dullness. Typically, distention is accompanied by sudden and severe abdominal pain that worsens with movement. Rebound tenderness and abdominal rigidity may be present.
Associated signs and symptoms usually include hypoactive or absent bowel sounds, fever, chills, hyperalgesia, nausea, and vomiting. Also, the skin over the patient’s abdomen may appear taut. Signs of shock, such as tachycardia and hypotension, appear with significant fluid loss into the abdomen.
Small-bowel obstruction
Abdominal distention, which is characteristic of small-bowel obstruction, is most pronounced during late obstruction, especially in the distal small bowel. Auscultation reveals hypoactive or hyperactive bowel sounds, whereas percussion produces a tympanic note. Accompanying signs and symptoms of this life-threatening disorder include colicky periumbilical pain, constipation, nausea, and vomiting; the higher the obstruction, the earlier and more severe the vomiting. Rebound tenderness reflects intestinal strangulation with ischemia. Associated signs and symptoms include drowsiness, malaise, and signs of dehydration. Signs of hypovolemic shock appear with progressive dehydration and plasma loss.
Toxic megacolon (acute)
Acute toxic megacolon is a life-threatening complication of infectious or ulcerative colitis. It produces dramatic abdominal distention that usually develops gradually and is accompanied by a tympanic percussion note, diminished or absent bowel sounds, and mild rebound tenderness. The patient also presents with abdominal pain and tenderness, fever, tachycardia, and dehydration.
Obesity:
Principal Causes of Obesity
(The Diagnostic Approach to Symptoms and Signs in Pediatrics)
- Geneticinfluences and environmental factors
- Endocrine disorders
- Glucocorticoidexcess
- Hypothyroidism
- Growth hormone deficiency
- Hypothalamic dysfunction
- Polycystic ovary syndrome
- Syndromes
- Alstrom syndrome
- Bardet-Biedl syndrome
- Carpenter syndrome
- Cohen syndrome
- Prader-Willi syndrome
Abdominal distention:
Medical causes
(Nursing: Interpreting Signs and Symptoms)
Abdominal cancer.Generalized abdominal distention may occur when the cancer—most commonly ovarian, hepatic, or pancreatic—produces ascites (usually in a patient with a known tumor). It's an indication of advanced disease. Shifting dullness and a fluid wave accompany distention. Associated signs and symptoms may include severe abdominal pain, an abdominal mass, anorexia, jaundice, GI hemorrhage (hematemesis or melena), dyspepsia, and weight loss that progresses to muscle weakness and atrophy.
Abdominal trauma.When brisk internal bleeding accompanies trauma, abdominal distention may be acute and dramatic. Associated signs and symptoms of this life-threatening disorder include abdominal rigidity with guarding, decreased or absent bowel sounds, vomiting, tenderness, and abdominal bruising. Pain may occur over the trauma site, or over the scapula if abdominal bleeding irritates the phrenic nerve. Signs of hypovolemic shock (such as hypotension and rapid, thready pulse) appear with significant blood loss.
Cirrhosis.In cirrhosis, ascites causes generalized distention and is confirmed by a fluid wave, shifting dullness, and a puddle sign. Umbilical eversion and caput medusae (dilated veins around the umbilicus) are common. The pa-tient may report a feeling of fullness or weight gain. Associated findings include vague abdominal pain, fever, anorexia, nausea, vomiting, constipation or diarrhea, bleeding tendencies, severe pruritus, palmar erythema, spider angiomas, leg edema, and possibly splenomegaly. Hematemesis, encephalopathy, gynecomastia, or testicular atrophy may also be seen. Jaundice is usually a late sign. Hepatomegaly occurs initially, but the liver may not be palpable if the patient has advanced disease.
Heart failure.Generalized abdominal distention due to ascites typically accompanies severe cardiovascular impairment and is confirmed by shifting dullness and a fluid wave. Signs and symptoms of heart failure are numerous and depend on the disease stage and degree of cardiovascular impairment. Hallmarks include peripheral edema, jugular vein distention, dyspnea, and tachycardia. Common associated signs and symptoms include hepatomegaly (which may cause right upper quadrant pain), nausea, vomiting, a productive cough, crackles, cool extremities, cyanotic nail beds, nocturia, exercise intolerance, nocturnal wheezing, diastolic hypertension, weight gain, and cardiomegaly.
Irritable bowel syndrome.Irritable bowel syndrome may produce intermittent, localized distention—the result of periodic intestinal spasms. Lower abdominal pain or cramping typically accompanies these spasms. The pain is usually relieved by defecation or by passage of intestinal gas and is aggravated by stress. Other possible signs and symptoms include diarrhea that may alternate with constipation or normal bowel function, nausea, dyspepsia, straining and urgency at defecation, a feeling of incomplete evacuation, and small, mucus-streaked stools.
Large-bowel obstruction.Dramatic abdominal distention is characteristic in this life-threatening disorder; in fact, loops of the large bowel may become visible on the abdomen. Constipation precedes distention and may be the only symptom for days. Associated findings include tympany, high-pitched bowel sounds, and the sudden onset of colicky lower abdominal pain that becomes persistent. Nausea, fecal vomiting, and diminished peristaltic waves and bowel sounds are late signs.
Mesenteric artery occlusion (acute). In this life-threatening disorder, abdominal distention usually occurs several hours after the sudden onset of severe, colicky periumbilical pain accompanied by rapid (even forceful) bowel evacuation. The pain later becomes constant and diffuse. Related signs and symptoms include severe abdominal tenderness with guarding and rigidity, absent bowel sounds and, occasionally, a bruit in the right iliac fossa. The patient may also experience vomiting, anorexia, diarrhea, or constipation. Late signs include fever, tachycardia, tachypnea, hypotension, and cool, clammy skin. Abdominal distention or GI bleeding may be the only clue if pain is absent.
Paralytic ileus.Paralytic ileus, which produces generalized distention with a tympanic percussion note, is accompanied by absent or hypoactive bowel sounds and, occasionally, mild abdominal pain and vomiting. The patient may be severely constipated or may pass flatus and small, liquid stools.
Peritonitis.Peritonitis is a life-threatening disorder in which abdominal distention may be localized or generalized, depending on the extent of the inflammation. Fluid accumulates within the peritoneal cavity and then within the bowel lumen, causing a fluid wave and shifting dullness. Typically, distention is accompanied by sudden and severe abdominal pain that worsens with movement, rebound tenderness, and abdominal rigidity.
The skin over the patient's abdomen may appear taut. Associated signs and symptoms usually include hypoactive or absent bowel sounds, fever, chills, hyperalgesia, nausea, and vomiting. Signs of shock, such as tachycardia and hypotension, appear with significant fluid loss into the abdomen.
Small-bowel obstruction.Abdominal distention is characteristic in small-bowel obstruction, a life-threatening disorder, and is most pronounced during late obstruction, especially in the distal small bowel. Auscultation reveals hypoactive or hyperactive bowel sounds, whereas percussion produces a tympanic note. Accompanying signs and symptoms include colicky periumbilical pain, constipation, nausea, and vomiting; the higher the obstruction, the earlier and more severe the vomiting. Rebound tenderness reflects intestinal strangulation with ischemia. Associated signs and symptoms include drowsiness, malaise, and signs of dehydration. Signs of hypovolemic shock appear with progressive dehydration and plasma loss.
Toxic megacolon (acute).Toxic megacolon is a life-threatening complication of infectious or ulcerative colitis. It produces dramatic abdominal distention that usually develops gradually and is accompanied by a tympanic percussion note, diminished or absent bowel sounds, and mild rebound tenderness. The patient also presents with abdominal pain and tenderness, fever, tachycardia, and dehydration.
Obesity as a complication of other conditions:
Other conditions that might have Obesity as a complication may, potentially, be an underlying cause of Obesity. Our database lists the following as having Obesity as a complication of that condition:
- Binge eating disorder
- Cushing's syndrome
- Metabolic Syndrome
- Physical inactivity
- Polycystic ovary syndrome
- Williams Syndrome
Obesity as a symptom:
Conditions listing Obesity as a symptom may also be potential underlying causes of Obesity. Our database lists the following as having Obesity as a symptom of that condition:
- Achard-Thiers Syndrome
- Adrenal Cancer
- Albright like syndrome
- Albright's hereditary osteodystrophy
- Ampola syndrome
- Aniridia - ptosis - mental retardation - obesity, familial
- Anophthalmia - short stature - obesity
- Aromatase deficiency
- Ayazi syndrome
- Bardet-Biedl Syndrome
- Bardet-Biedl syndrome, type 1
- Bardet-Biedl syndrome, type 10
- Bardet-Biedl syndrome, type 11
- Bardet-Biedl syndrome, type 12
- Bardet-Biedl syndrome, type 2
- Bardet-Biedl syndrome, type 3
- Bardet-Biedl syndrome, type 4
- Bardet-Biedl syndrome, type 5
- Bardet-Biedl syndrome, type 6
- Bardet-Biedl syndrome, type 7
- Bardet-Biedl syndrome, type 8
- Bardet-Biedl syndrome, type 9
- Bearn-Kunkel syndrome
- Biemond syndrome type 2
- Binge eating disorder
- Bobble-head doll syndrome
- Cardiomyopathy - hypogonadism - metabolic anomalies
- Carpenter syndrome
- Chondrodysplasia, Grebe type
- Choroideremia
- Chromosome 12p tetrasomy syndrome
- Chromosome 21q deletion syndrome
- Chromosome 3, trisomy 3q13 2 q25
- Chromosome 4, trisomy 4p
- Chromosome 5q duplication syndrome
- Clark-Baraitser syndrome
- Cohen Syndrome
- Deletion 6q16 q21
- Eating disorders
- Emerinopathy
- Empty sella syndrome - acquired
- Empty sella syndrome - primary
- Frölich's syndrome
- Fructose-1,6-bisphosphatase deficiency, hereditary
- Grahmann's syndrome
- HAIR-AN Syndrome
- Hyperandrogenism
- Hyperostosis frontalis interna
- Hyperpituitarism
- Hypertrichosis brachydactyly obesity and mental retardation
- Hypogonadism - mitral valve prolapse - mental retardation
- Hypogonadotropic hypogonadism - syndactyly
- Laron syndrome type 1
- Laron syndrome type 2
- Laron-type dwarfism
- Leschke-Ullmann syndrome
- Mauriac syndrome
- Mental retardation - blepharophimosis - obesity - web neck
- Mental retardation - epilepsy - bulbous nose
- Mental retardation - epileptic seizures - hypogonadism - hypogenitalism -microcephaly - obesity
- Mental retardation - gynecomastia - obesity, X-linked
- Mental retardation - nasal hypoplasia - obesity - genital hypoplasia
- Mental retardation X-linked syndromic 7
- Mental retardation, X linked - precocious puberty - obesity
- Mental retardation, X-linked - gynecomastia - obesity
- Mental retardation, X-linked - hypogonadism - ichthyosis - obesity - short stature
- Mental retardation, X-linked, 36
- Mental retardation, X-linked, syndromic 11
- Metabolic Syndrome
- Metaphyseal dysostosis mental retardation conductive deafness
- MOMO syndrome
- Nguyen syndrome
- Obesity - colitis - hypothyroidism - cardiac hypertrophy - developmental delay
- Obesity due to congenital leptin deficiency
- Obesity, hypothyroidism, craniosynostosis, cardial hypertrophy, colitis and intellectual deficiency
- Polycystic ovarian disease, familial
- Polycystic ovary syndrome
- Polyneuropathy - mental retardation - acromicria - premature menopause
- Prader-Willi syndrome
- Retinohepatoendocrinologic syndrome
- Schinzel Syndrome
- Schroeder syndrome 1
- Sengers-Hamel-Otten syndrome
- Simpson-Golabi-Behmel syndrome, type 1 (SGBS1)
- Simpson-Golabi-Behmel syndrome, type 2
- Sohval-Soffer syndrome
- Subaortic stenosis - short stature syndrome
- Summitt syndrome
- Urban rogers meyer syndrome
- Vasquez Hurst Sotos syndrome
- Weight cycling
- Wilson-Turner X-linked mental retardation
- X-linked mental retardation craniofacial abnormal microcepahly club
- Young Hughes syndrome
What causes Obesity?
Causes: Obesity:
Although some obesity is caused by underlying disorders,
the main cause is probably lifestyle.
The problem has two basic issues: too much food, too little activity.
High calorie diets from processed foods and fats make it easy to add weight.
Sedentary lifestyles without adequate exercise make it hard to take weight off.
Evidence suggests that obesity has more than one cause: genetic, environmental, psychological and other factors may all play a part.
(Source: Genes and Disease by the National Center for Biotechnology)
Article excerpts about the
causes of Obesity:
Understanding Adult Obesity: NIDDK (Excerpt)
In scientific terms, obesity occurs when a person consumes more calories than he or she burns. What causes this imbalance between calories in and calories out may differ from one person to another. Genetic, environmental, psychological, and other factors may all play a part.
Genetic factors
Obesity tends to run in families, suggesting a genetic cause. Yet families also share diet and lifestyle habits that may contribute to obesity. Separating these from genetic factors is often difficult. Even so, science shows that heredity is linked to obesity.
In one study, adults who were adopted as children were found to have weights closer to their biological parents than to their adoptive parents. In this case, the person's genetic makeup had more influence on the development of obesity than the environment in the adoptive family home.
Environmental factors
Genes do not destine people to a lifetime of obesity, however. Environment also strongly influences obesity. This includes lifestyle behaviors such as what a person eats and his or her level of physical activity. Americans tend to eat high-fat foods, and put taste and convenience ahead of nutrition. Also, most Americans do not get enough physical activity.
Although you cannot change your genetic makeup, you can change your eating habits and levels of activity. Try these techniques that have helped some people lose weight and keep it off:
- Learn how to choose more nutritious meals that are lower in fat.
- Learn to recognize and control environmental cues (like inviting smells) that make you want to eat when you're not hungry.
- Become more physically active.
- Keep records of your food intake and physical activity.
Psychological factors
Psychological factors may also influence eating habits. Many people eat in response to negative emotions such as boredom, sadness, or anger.
Most overweight people have no more psychological problems than people of average weight. Still, up to 10 percent of people who are mildly obese and try to lose weight on their own or through commercial weight loss programs have binge eating disorder. This disorder is even more common in people who are severely obese.
During a binge eating episode, people eat large amounts of food and feel that they cannot control how much they are eating. Those with the most severe binge eating problems are also likely to have symptoms of depression and low self-esteem. These people may have more difficulty losing weight and keeping it off than people without binge eating problems.
If you are upset by binge eating behavior and think you might have binge eating disorder, seek help from a health professional such as a psychiatrist, psychologist, or clinical social worker. (Source: excerpt from Understanding Adult Obesity: NIDDK)
Prescription Medications for the Treatment of Obesity: NIDDK (Excerpt)
Obesity often is viewed as the result of a lack of willpower, weakness, or a lifestyle "choice"--the choice to overeat and underexercise. The belief that persons choose to be obese adds to the hesitation of health professionals and patients to accept the use of long-term appetite-suppressant medication treatment to manage obesity. Obesity, however, is more appropriately considered a chronic disease than a lifestyle choice (Source: excerpt from Prescription Medications for the Treatment of Obesity: NIDDK)
Obesity: NWHIC (Excerpt)
The main causes of being overweight or obese are eating too much and/or not being active enough. If you eat more calories than your body burns up, the extra calories are stored as fat. Everyone has some stored fat. Too much fat results in being overweight or obese. Other factors that may affect your weight include your genes (obesity tends to run in families), your metabolism (how your body processes food), your racial/ethnic group, and your age. Sometimes an illness or medicine can contribute to weight gain. Researchers are studying the causes of obesity to learn more about how to prevent and reverse it. (Source: excerpt from Obesity: NWHIC)
Medical news summaries relating to Obesity:
The following medical news items are relevant to causes of Obesity:
- 52% of British people fear exercise for one reason or another
- All about obesity
- Babies with large appetite become heavier adults
- Cancer deaths take over deaths caused by heart disease
- Candida influenced by obesity and depression
- Childhood obesity tripling in concern
- Children increasingly face adult diseases
- Current trends in health
- Diabetes exercise link
- Diabetes: the simple facts
- Diabetics are more prone to the potentially fatal bacteremia and sepsis
- Dollars dictate diet
- Eating for your health
- Fast food linked to weight increase and diabetes
- Food industry protected against obesity lawsuits
- Fries factor in breast cancer
- GI diet to assist cystic ovary disease
- Kidney disease goes in hand with obesity
- Kidney stone risk increased by obesity
- Lack of sleep influences illnesses
- Liver disease is one of the biggest killers amongst diabetics
- Metabolic syndrome (X)
- Metabolic syndrome can be treated with a low carbohydrate diet and exercise
- New Dietary Guidelines support numerous research results
- New risk factors may be associated with cardiovascular disease risk
- Obesity is associated with an increased risk of many conditions
- Obesity leads to liver disease
- Obesity linked to esophageal precancerous condition
- Operation options for obesity
- Overweight pregnant mothers risk future obesity in offspring
- Pancreatic cancer surgery less common in black men
- PCOS may be improved by the diet drug Xenical
- Plant protein may protect against some human diseases
- Researchers discover part of brain that is partly responsible for weight control
- Scientists examine effects of lack of activity
- Scientists find exercise secrets in order to develop a pill to take the place of exercise
- Sleep deprivation linked to obesity
- Sleeping problems pose high risk for adverse health effects
- Some antipsychotic drugs linked to increased risk of developing type 2 diabetes
- Some health facts about diet soda
- Warning signs of a heart attack
- Weighty issue for men
- WHO concerned with increase incidence in stroke and heart disease
Related information on causes of Obesity:
As with all medical conditions, there may be many causal factors. Further relevant information on causes of Obesity may be found in:
» Next page: Risk Factors for Obesity
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- Risk Factors for Obesity
- Symptoms of Obesity
- Diagnostic Tests for Obesity
- Diagnosis of Obesity
- Signs of Obesity
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