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Diseases » Optic neuritis » Diagnosis
 

Diagnosis of Optic neuritis

Diagnostic Test list for Optic neuritis:

The list of medical tests mentioned in various sources as used in the diagnosis of Optic neuritis includes:

Optic neuritis Diagnosis: Book Excerpts

Diagnostic Tests for Optic neuritis: Online Medical Books

16 MEDICAL BOOKS ONLINE! Review excerpts from medical books online, free, without registration, for more information about diagnostis of Optic neuritis.


Vision Loss: Differential Diagnosis
(In a Page: Signs and Symptoms)

Transient vision loss (<24 hours)

  • Papilledema: Lasts seconds, bilateral
  • Amaurosis fugax: Lasts minutes, unilateral
  • Vertebrobasilar artery insufficiency: Lasts minutes, bilateral
  • Migraine: Lasts 10–60 minutes
  • Impending central retinal vein occlusion
  • Ocular ischemic syndrome (carotid occlusive disease)
  • Sudden change in blood pressure; orthostatic hypotension
    • Transient acute increase in intraocular pressure (e.g., acute angle closure glaucoma, retro- or peribulbar hemorrhage)

    Vision loss >24 hours: Sudden, painless
  • Retinal artery or vein occlusion
  • Ischemic optic neuropathy (must rule out giant cell/temporal arteritis to prevent permanent bilateral vision loss)
  • Vitreous or aqueous hemorrhage (hyphema)
  • Retinal detachment
  • Other retinal or CNS disease (e.g., cortical blindness due to occipital lobe CVA)
  • Exposure (“Welder's flash”) or prolonged exposure to intense sunlight

Vision loss >24 hours: Gradual, painless
  • Cataract
  • Refractive error
  • Open angle glaucoma
  • Chronic retinopathy (e.g., age-related macular degeneration, diabetic retinopathy)
  • Chronic corneal disease (e.g., corneal dystrophy)
  • Optic neuropathy/atrophy (e.g., compressive lesion, toxic-metabolic cause, dominant optic neuropathy, radiation)
  • Retinitis pigmentosa
  • Pseudotumor cerebri

  • Vision loss >24 hours: Painful
  • Acute angle closure glaucoma
  • Optic neuritis (pain with extraocular motion)
  • Orbital apex/superior orbital fissure/ cavernous sinus syndrome
  • Uveitis
  • Corneal hydrops (keratoconus)
    • Ocular onchocerciasis (“river blindness”)
      –Common cause of blindness in developing nations due to Onchocerca volvulus worm
    • Corneal abrasion or ulcer
    • Herpes simplex or zoster infection

    Workup and Diagnosis

    • History should include age, onset, tempo of vision loss, history of trauma, associated headache, medications, past history (e.g., carotid or cardiac disease, HTN, diabetes, vertigo, migraine, syphilis, ocular, orbital, cranial radiation, keratoconus), family history of vision loss, alcohol and tobacco use
    • Physical exam should include a thorough eye examination, vision acuity, refractive error, color vision, blood pressure, refractive error, cranial examination, cranial nerve innervation, intraocular pressure, ocular media opacity (corneal edema, dystrophy, anterior chamber or vitreous cells, cataracts), and fundus and optic disc exam
    • Consider a visual field exam and fluorescein angiogram
    • Initial laboratory evaluation may include ESR, CRP, fasting blood glucose, HgbA1C, PPD, RPR, FTA-ABS, ACE level, vitamin B12, and folate
    • Consider CT/MRI of orbits and head with contrast, carotid Doppler, echocardiogram, electroretinography, and VEP (retinal dystrophies, optic neuropathies, nonphysiologic)
    • Consider ophthalmologic consultation
    '>

    » READ BOOK EXCERPT ONLINE »

    Source: In a Page: Signs and Symptoms, 2004

    Vision Loss: Differential Diagnosis
    (In A Page: Pediatric Signs and Symptoms)

    • Vascular causes
      –Amaurosis fugax: TIA of the retina lasting 5–60 minutes
      –Stroke causes loss of side vision usually to the left or right, may be interpreted as loss of vision in the right or left eye
      –Retinal vascular occlusion: Venous shows gradual decline with retinal hemorrhaging; arterial has sudden onset with minimal to no retinal hemorrhaging
      • Transient monocular blindness (TMB)
        –Lasts seconds
        –Due to positional changes in optic disc edema with increased intracranial hypertension, orthostatic hypotension, thyroid eye disease, and space-occupying lesions
    • Migraine variants are transient and may be associated with headache after presentation
    • Optic nerve edema or swelling from demyelinating disease, nonarteritic and arteritic optic neuropathy, toxicity (e.g., lead, chloramphenicol)
    • Optic atrophy
      • Retinal etiologies
        –Retinal surface wrinkling disorders
        –Idiopathic central serous retinopathy often associated with stress
        –Retinal detachment with probable history of floaters before loss of vision
    • Angle closure glaucoma
      • Postsurgical
        –Endophthalmitis: Often associated with ocular surgery and red eye
        –Cystoid macular edema may occur after ocular surgery
    • Vitreous hemorrhage
      –You will not be able to see into the eye
      • Infectious causes
        –Retinitis and/or uveitis due to toxoplasmosis, cytomegalovirus, Lyme, histoplasmosis
    • Trauma
    • Hysterical blindness
    • Cataracts
    • Hypoglycemia
    • Retinitis pigmentosa

    Workup and Diagnosis

  • History
    –Be aware that patients often have vision reduction over time (e.g., from cataracts) and only perceive the loss as sudden
    –Onset, duration, trauma; transience vs permanence of visual loss or change
    –Associated signs and symptoms of demyelinizing disease, toxoplasmosis, bartonellosis, Lyme disease
    –PMH including migraines, hypertension, diabetes, thyroid disease, rheumatic disease, vascular disease, atrial fibrillation, lipid status
    • Physical exam
      –Obtain visual acuity and confrontation visual fields in both eyes
      –Redness, pain, photophobia
      –Pupillary evaluation: look for Marcus Gunn pupil, which usually differentiates optic nerve from other causes
      –Extraocular muscle evaluation
      –Perform a dilated fundus evaluation
      –Evaluate for proptosis
      • Radiology
        –CT or MRI of orbits and brain is indicated for associated neurologic signs, history of trauma
    • Evaluation for stroke if right- or left-sided
    • Ophthalmology consultation for dilated retinal exam, evaluation, and management

    » READ BOOK EXCERPT ONLINE »

    Source: In A Page: Pediatric Signs and Symptoms, 2007

    Vision loss: History and physical examination
    (Handbook of Signs & Symptoms (Third Edition))

    Sudden vision loss can signal an ocular emergency. (See Managing sudden vision loss.) Don’t touch the eye if the patient has perforating or penetrating ocular trauma.

    If the patient’s vision loss occurred gradually, ask him if the vision loss affects one eye or both and all or only part of the visual field. Is the visual loss transient or persistent? Did the visual loss occur abruptly, or did it develop over hours, days, or weeks? What is the patient’s age? Ask the patient if he has experienced photosensitivity, and ask him about the location, intensity, and duration of any eye pain. You should also obtain an ocular history and a family history of eye problems or systemic diseases that may lead to eye problems, such as hypertension; diabetes mellitus; thyroid, rheumatic, or vascular disease; infections; and cancer.

    The first step in performing the eye examination is to assess visual acuity, with best available correction in each eye. (See Testing visual acuity, page 630.)

    Carefully inspect both eyes, noting edema, foreign bodies, drainage, or conjunctival or scleral redness. Observe whether lid closure is complete or incomplete, and check for ptosis. Using a flashlight, examine the cornea and iris for scars, irregularities, and foreign bodies. Observe the size, shape, and color of the pupils, and test the direct and consensual light reflex (See “Pupils, nonreactive,” page 521.) and the effect of accommodation. Evaluate extraocular muscle function by testing the six cardinal fields of gaze. (See Testing extraocular muscles, page 206.)

    » READ BOOK EXCERPT ONLINE »

    Source: Handbook of Signs & Symptoms (Third Edition), 2006

    Vision loss: History and physical examination
    (Professional Guide to Signs & Symptoms (Fifth Edition))

    Sudden vision loss can signal an ocular emergency. Don’t touch the eye if the patient has a perforating or penetrating ocular trauma. (See Managing sudden vision loss, page 802.)

    If the patient’s vision loss occurred gradually, ask him if it affects one eye or both and all or only part of the visual field. Is the vision loss transient or persistent? Did it occur abruptly or develop over hours, days, or weeks? What is the patient’s age? Ask the patient if he has experienced photosensitivity, and ask about the location, intensity, and duration of any eye pain. Also, obtain an ocular history and a family history of eye problems or systemic diseases that may lead to eye problems, such as hypertension; diabetes mellitus; thyroid, rheumatic, or vascular disease; infections; and cancer.

    The first step in performing the eye examination is to assess visual acuity with the best available correction in each eye. (See Testing visual acuity, page 803.)

    Carefully inspect both eyes, noting edema, foreign bodies, drainage, or conjunctival or scleral redness. Observe whether lid closure is complete or incomplete, and check for ptosis. Using a flashlight, examine the cornea and iris for scars, irregularities, and foreign bodies. Observe the size, shape, and color of the pupils, and test the direct and consensual light reflex (see “Pupils, nonreactive,” page 654) and the effect of accommodation. Evaluate extraocular muscle function by testing the six cardinal fields of gaze. (See Testing extraocular muscles, page 246.)

    » READ BOOK EXCERPT ONLINE »

    Source: Professional Guide to Signs & Symptoms (Fifth Edition), 2006

    Vision loss: History
    (Alarming Signs and Symptoms: Lippincott Manual of Nursing Practice Series)

    Sudden vision loss can signal an ocular emergency. Don’t touch the eye if the patient has perforating or penetrating ocular trauma.

    If the patient’s vision loss occurred gradually, ask him if it developed over hours, days, or weeks. Does it affect one eye or both? Does it affect all or part of the visual field? Is the vision loss transient or persistent? What’s the patient’s age? Ask whether he has experienced photosensitivity, and ask him about the location, intensity, and duration of eye pain. Obtain an ocular history, including history of eye problems or systemic diseases that may lead to eye problems, such as infections, cancer, hypertension, diabetes mellitus, and thyroid, rheumatic, or vascular disease.

    Physical examination

    Assess visual acuity and determine the best available vision correction in each eye. (See Testing visual acuity.)

    Carefully inspect both eyes, noting edema, foreign bodies, drainage, or conjunctival or scleral redness. Observe whether lid closure is complete or incomplete, and check for ptosis. Using a flashlight, examine the cornea and iris for scars, irregularities, and foreign bodies. Evaluate extraocular muscle function by testing the six cardinal fields of gaze. (See Testing extraocular muscles, page 306.) Observe the size, shape, and color of the pupils, and test the direct and consensual light reflex and the effect of accommodation. (See Vision loss: Causes and associated findings, pages 308 and 309.)

    » READ BOOK EXCERPT ONLINE »

    Source: Alarming Signs and Symptoms: Lippincott Manual of Nursing Practice Series, 2007

    Vision loss: History
    (Signs & Symptoms: A 2-in-1 Reference for Nurses)

    Sudden vision loss can signal an ocular emergency. (See Managing sudden vision loss, page 690.)

    If the patient’s vision loss occurred gradually, ask him if the vision loss affects one eye or both and all or only part of the visual field. Is the visual loss transient or persistent? Did the visual loss occur abruptly, or did it develop over hours, days, or weeks? What is the patient’s age? Ask the patient if he has experienced photosensitivity, and ask him about the location, intensity, and duration of any eye pain. You should also obtain an ocular history and a family history of eye problems or systemic diseases that may lead to eye problems, such as hypertension; diabetes mellitus; thyroid, rheumatic, or vascular disease; infections; and cancer.

    » READ BOOK EXCERPT ONLINE »

    Source: Signs & Symptoms: A 2-in-1 Reference for Nurses, 2007

    Vision loss: History and physical examination
    (Nursing: Interpreting Signs and Symptoms)

    Sudden vision loss can signal an ocular emergency. (See Managing sudden vision loss, page 628.) Don't touch the eye if the patient has perforating or penetrating ocular trauma.

    If the patient's vision loss occurred gradually, ask him if the vision loss affects one eye or both and all or only part of the visual field. Is the visual loss transient or persistent? Did the vision loss occur abruptly or did it develop over hours, days, or weeks? What's the patient's age? Ask the patient if he has experienced photosensitivity and ask him about the location, intensity, and duration of eye pain. You should also obtain an ocular history and a family history of eye problems or systemic diseases that may lead to eye problems, such as hypertension; diabetes mellitus; thyroid, rheumatic, or vascular disease; infections; and cancer.

    The first step in performing an eye examination is to assess visual acuity, with best available correction in each eye. (See Testing visual acuity, page 629.)

    Carefully inspect both eyes, noting edema, foreign bodies, drainage, or conjunctival or scleral redness. Observe whether lid closure is complete or incomplete and check for ptosis. Using a flashlight, examine the cornea and iris for scars, irregularities, and foreign bodies. Observe the size, shape, and color of the pupils, and test the direct and consensual light reflex (See “Pupils, nonreactive,” page 515.) and the effect of accommodation. Evaluate extraocular muscle function by testing the six cardinal fields of gaze. (See Testing extraocular muscles, page 197.)

    » READ BOOK EXCERPT ONLINE »

    Source: Nursing: Interpreting Signs and Symptoms, 2007


     » Next page: Signs of Optic neuritis

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