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Osteomalacia

Osteomalacia: Excerpt from A Pocket Manual of Differential Diagnosis

Vitamin D deficiency
   Dietary deficiency
   Insufficient sun exposure
   Malabsorption (e.g., pancreatic insufficiency, small-
intestine disease, postgastrectomy)
Disordered vitamin D metabolism (hereditary or acquired)
   Chronic renal failure
   Anticonvulsant therapy
   Chronic liver disease (e.g., biliary cirrhosis)
Peripheral resistance to vitamin D (e.g., vitamin D–dependent rickets)
Chronic acidosis (e.g., distal renal tubular acidosis, chronic acetazolamide ingestion, ureterosigmoidostomy)
Phosphate depletion
Impaired renal tubular phosphate resorption
   Familial X-linked hypophosphatemia
   Fanconi syndrome (hereditary or acquired)
   Tumor phosphaturia
   Neurofibromatosis
   Neonatal (transient)
   Intoxications (cadmium, lead, outdated tetracycline,
aluminum)
Miscellaneous
   Osteopetrosis
   Hypophosphatasia
   Fluorosis
   Magnesium-dependent conditions
   Parenteral hyperalimentation
   Renal transplantation
   Tumor-associated renal disease
   Calcium deficiency due to biophosphonates

References

1. Raisy LG: Metabolic Bone Disease, p. 1228. See Bibliography, 4.
2. Krane SM, Holick MF: Metabolic Bone Disease, p. 2253. See Bibliography, 1.

Book Source Details

• Book Title: A Pocket Manual of Differential Diagnosis
• Author(s): Stephen N. Adler, Dianne B. Gasbarra
• Year of Publication: 1999
• Copyright Details: A Pocket Manual of Differential Diagnosis, Copyright © 1999 Lippincott Williams & Wilkins.

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• Back to disease: Osteomalacia: Introduction
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Copyright notice for book excerpts: Copyright © 2008 Lippincott Williams & Wilkins. All rights reserved.

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More About This Book: Title: A Pocket Manual of Differential Diagnosis Authors: Stephen N. Adler, Dianne B. Gasbarra Publisher: Lippincott Williams & Wilkins Copyright: 1999 ISBN: 0-78171-943-7

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