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Causes of Osteomalacia
List of causes of Osteomalacia
Following is a list of causes or underlying conditions (see also Misdiagnosis of underlying causes of Osteomalacia) that could possibly cause Osteomalacia includes:
- Vitamin D deficiency
- Malabsorption
- Inadequate sunlight exposure
- Hypocalcemia
Causes of Osteomalacia (Diseases Database):
The follow list shows some of the possible medical causes of Osteomalacia that are listed by the Diseases Database:
- Hypophosphataemia
- Cystinosis
- Renal failure, chronic
- Wilson's disease
- Hypophosphatasia
- Ethotoin
- Nephropathic early-onset cystinosis
- Proximal renal tubular acidosis
- Vitamin D dependent rickets type 1
- Vitamin D dependent rickets type 2a
- Hypokalaemic distal renal tubular acidosis
- Phenytoin
- Autosomal dominant hypophosphatemic rickets
- Malabsorption syndrome
- Glutethimide
- X-linked hypophosphataemia
- Etidronate
- Vitamin D deficiency
Osteomalacia as a complication of other conditions:
Other conditions that might have Osteomalacia as a complication may, potentially, be an underlying cause of Osteomalacia. Our database lists the following as having Osteomalacia as a complication of that condition:
- Renal tubular acidosis progressive nerve deafness
- Renal tubular acidosis, distal
- Renal tubular acidosis, distal - type I
- Renal tubular acidosis, distal - type III
Osteomalacia as a symptom:
Conditions listing Osteomalacia as a symptom may also be potential underlying causes of Osteomalacia. Our database lists the following as having Osteomalacia as a symptom of that condition:
- Acid phosphatase deficiency
- Acid-Base Imbalance
- Adult hypophosphatasia
- Aluminium toxicity
- Cholestasis
- Fanconi renotubular syndrome
- Fanconi syndrome
- Hereditary primary Fanconi disease
- Hypophosphatemia, Familial
- Primary biliary cirrhosis
- Renal Tubular Acidosis
- Renal tubular acidosis, distal, autosomal dominant
- Toni-Fanconi syndrome type 1
- Vitamin D deficiency
Drug interactions causing Osteomalacia:
When combined, certain drugs, medications, substances or toxins may react causing Osteomalacia as a symptom.
The list below is incomplete and various other drugs or substances may cause your symptoms. Always advise your doctor of any medications or treatments you are using, including prescription, over-the-counter, supplements, herbal or alternative treatments.
- Ergocalciferol and Phenytoin interaction
- Phenytoin and Acetazolamide interaction
- Dilantin and Acetazolamide interaction
- Dilantin Infatabs and Acetazolamide interaction
- Dilantin w/Phenobarbital and Acetazolamide interaction
- more interactions...»
See full list of 23 drug interactions causing Osteomalacia
Related information on causes of Osteomalacia:
As with all medical conditions, there may be many causal factors. Further relevant information on causes of Osteomalacia may be found in:
Causes of Osteomalacia: Online Medical Books
16 MEDICAL BOOKS ONLINE! Review excerpts from medical books online, free, without registration, for more information about the causes of Osteomalacia.
Rickets:
Rickets - description_causes
(The 5-Minute Pediatric Consult)
- See table “Causes and Management of Rickets.”
Causes and Management of Rickets
| CAUSE | MANAGEMENT | ||||||||||||||||||||||||||||
| Calcium deficiency | |||||||||||||||||||||||||||||
| Low intake | <6 months of age 400 mg/day6–12 months of age 600 mg/day1–10 years of age 800 mg/day | ||||||||||||||||||||||||||||
| Extreme prematurity (birth weight <1,500 g) | Adjust intake to 200 mg/kg/day | ||||||||||||||||||||||||||||
| Steatorrhea | 25-OH-D| Anticonvulsant (Phenobarbital or phenytoin) | Calcium<6 months of age 400 mg/day6–12 months of age 600 mg/day1–10 years of age 800 mg/dayVitamin D200 IU/day of ergocalciferol | Renal tubular acidosis | Base supplement: 3–10 mM/kg/d as NaHCO | Vitamin D deficiency | | Insufficient UV light exposure | 200 IU/day of vitamin D of ergocalciferol | Breastfeed infants who are not supplemented with vitamin D | 200 IU/day of vitamin D of ergocalciferol | Liver disease | 4,000–8,000 IU/day ergocalciferol | Renal disorders | 4,000–40,000 IU/day of Calcitriol | Nutritional rickets and osteomalacia | 1,000–5,000 IU/day of ergocalciferol | Vitamin D dependent rickets | 3,000–5,000 IU/day of Calcitriol | Vitamin D-resistant rickets | 40,000–80,000 IU/day of ergocalciferol with phosphate supplements, daily dosage is increased at 3–4 month intervals in 10,000–20,000 IU increments | Phosphorus deficiency | | Diet (limited to premature infants) | Adjust formula or parenteral source to give 10 mg/kg/d | Antacid excess | Alternative gastric acid control | Excessive phosphaturia from tubular dysfunction | Supplemental P and calcitriol if low | |
Source: The 5-Minute Pediatric Consult, 2008
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