Causes of Osteomyelitis
List of causes of Osteomyelitis
Following is a list of causes or underlying conditions
(see also Misdiagnosis of underlying causes of Osteomyelitis)
that could possibly cause Osteomyelitis includes:
More causes:
see full list of causes for Osteomyelitis
Causes of Osteomyelitis (Diseases Database):
The follow list shows some of the possible medical causes of Osteomyelitis
that are listed by the Diseases Database:
Source: Diseases Database
Osteomyelitis Causes: Book Excerpts
Osteomyelitis as a complication of other conditions:
Other conditions that might have
Osteomyelitis as a complication may,
potentially, be an underlying cause of Osteomyelitis.
Our database lists the following as having
Osteomyelitis as a complication of that condition:
Osteomyelitis as a symptom:
Conditions listing Osteomyelitis
as a symptom may also be potential underlying causes of Osteomyelitis.
Our database lists the following as having
Osteomyelitis as a symptom of that condition:
What causes Osteomyelitis?
Causes: Osteomyelitis:
Usually bacterial infection such as staphyloccus.
Related information on causes of Osteomyelitis:
As with all medical conditions,
there may be many causal factors.
Further relevant information on causes of Osteomyelitis may be found in:
Causes of Osteomyelitis: Online Medical Books
16 MEDICAL BOOKS ONLINE!
Review excerpts from medical books online, free, without registration,
for more information about the causes of Osteomyelitis.
Osteomyelitis:
Causes and incidence
(Professional Guide to Diseases (Eighth Edition))
Virtually any pathogenic bacteria can cause osteomyelitis under the right circumstances. Typically, these organisms find a culture site in a hematoma from recent trauma or in a weakened area, such as the site of surgery or local infection (for example, furunculosis), and spread directly to bone. As the organisms grow and form pus within the bone, tension builds within the rigid medullary cavity, forcing pus through the haversian canals. This forms a subperiosteal abscess that deprives the bone of its blood supply and may eventually cause necrosis. In turn, necrosis stimulates the periosteum to create new bone (involucrum); the old bone (sequestrum) detaches and works its way out through an abscess or the sinuses. By the time sequestrum forms, osteomyelitis is chronic.
Osteomyelitis occurs more commonly in children (especially boys) than in adults — usually as a complication of an acute localized infection. The most common sites in children are the lower end of the femur and the upper end of the tibia, humerus, and radius. The most common sites in adults are the pelvis and vertebrae, generally as a result of contamination associated with surgery or trauma. Other common sites are sternoclavicular, sacroiliac, and symphysis pubis. The incidence of both chronic and acute osteomyelitis is declining, except in drug abusers. With prompt treatment, the prognosis for acute osteomyelitis is very good; for chronic osteomyelitis, which is more prevalent in adults, the prognosis is still poor.
» READ BOOK EXCERPT ONLINE »
Source: Professional Guide to Diseases (Eighth Edition), 2005
Osteomyelitis:
Causes
(Handbook of Diseases)
The most common pyogenic organism in osteomyelitis is Staphylococcus aureus; others include Streptococcus pyogenes, Pneumococcus, Pseudomonas aeruginosa, Escherichia coli, and Proteus vulgaris. Typically, these organisms find a culture site in a hematoma from recent trauma or in a weakened area, such as the site of local infection (for example, furunculosis), and spread directly to bone.
As the organisms grow and form pus within the bone, tension builds within the rigid medullary cavity, forcing pus through the haversian canals. This forms a subperiosteal abscess that deprives the bone of its blood supply and eventually may cause necrosis. In turn, necrosis stimulates the periosteum to create new bone (involucrum); the old bone (sequestrum) detaches and works its way out through an abscess or the sinuses. By the time sequestrum forms, osteomyelitis is chronic.
» READ BOOK EXCERPT ONLINE »
Source: Handbook of Diseases, 2003
Osteomyelitis:
Osteomyelitis - risk factors
(The 5-Minute Pediatric Consult)
- Immunocompromised patients
- Increased incidence in patients with sickle cell disease and other immunodeficiencies
Osteomyelitis - pathophysiology
- Usually, osteomyelitis begins as bacteremia with hematogenous spread to the bone, but direct inoculation of bacteria into the bone by trauma is also possible.
- Most bacteria that enter the bone are phagocytized, so that no infection develops. When bacteria enter areas of the bone with low blood flow, however, such as the metaphysis directly beneath the physeal plate, they may not be phagocytized, and an infection may develop.
- The 1st changes noted in osteomyelitis are the death of the osteoblasts in the infected area and resorption of trabeculae. Inflammation develops, which further compromises blood flow, and microabscesses are formed within the bone. Pus can spread through the bone and between the bone and the periosteum. This pus can lift the periosteum, causing point tenderness.
Osteomyelitis - etiology
- Staphylococcus aureus causes 90% of osteomyelitis in otherwise healthy children of all ages.
- Streptococcus pyogenes or Haemophilus influenzae can also be the etiologic agent.
- Group B streptococci and Escherichia coli are often isolated in children <1 month of age.
- Salmonella can be the cause in children with sickle cell anemia.
- Pseudomonas aeruginosa can be found in puncture wounds to the foot.
>
» READ BOOK EXCERPT ONLINE »
Source: The 5-Minute Pediatric Consult, 2008
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