Paget's disease of bone

Introduction: Paget's disease of bone

Paget's disease of bone is a chronic bone disease. For the similarly named disease of the breast, see Paget's disease of breast.

Symptoms of Paget's disease of bone

• No early symptoms
• Vague symptoms
• Slowly developing bone pain
• Bone pain
• Enlarged bones

See full list of 45 symptoms of Paget's disease of bone

Medical Textbooks Online about Paget's disease of bone

Book excerpts: Copyright © 2008 Lippincott Williams & Wilkins. All rights reserved.

Diagnostic Tests for Paget's disease of bone

• X-rays
• Blood tests
• Urine tests

Read more about tests for Paget's disease of bone

Wrongly Diagnosed with Paget's disease of bone?

• Misdiagnosis of Paget's disease of bone

Misdiagnosis and Paget's disease of bone

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Read more about Misdiagnosis and Paget's disease of bone

Causes of Paget's disease of bone

Read more about causes of Paget's disease of bone.

Treatments for Paget's disease of bone

• Watchful waiting - if no symptoms, then sometimes no treatment is necessary.
• Pain relief
• Analgesics
• Aspirin
• NSAIDs

See full list of 8 treatments for Paget's disease of bone

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Patient Surveys for Paget's disease of bone

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Reseach about Paget's disease of bone

Visit our research pages for current research about Paget's disease of bone treatments.

Clinical Trials for Paget's disease of bone

The US based website ClinicalTrials.gov lists information on both federally and privately supported clinical trials using human volunteers.

Some of the clinical trials listed on ClinicalTrials.gov for Paget's disease of bone include:

• Safety and Efficacy Trial With Zoledronic Acid for the Treatment of Paget's Disease of Bone - This study is no longer recruiting patients (Current: 23 Nov 2006) - zoledronic acid
• 18F-Fluoride Positron Emission Tomography (PET) in Paget's Disease of Bone - This study has been completed (Current: 23 Nov 2006) - Bisphosphonate treatment
• Bisphosphonate Therapy for Osteogenesis Imperfecta - This study is currently recruiting patients (Current: 23 Nov 2006) - Alendronate,Pamidronate
• New Bisphosphonate Treatment for Paget's Disease - This study has been completed (Current: 23 Nov 2006) - Zoledronic Acid

Read more about Clinical Trials for Paget's disease of bone

Statistics for Paget's disease of bone

• Medical statistics for Paget's disease of bone
• Prevalence and incidence statistics for Paget's disease of bone
• Death and Mortality statistics for Paget's disease of bone
• Society statistics for Paget's disease of bone

Stories from Users Related to Paget's disease of bone

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Article Excerpts about Paget's disease of bone

Paget's disease of bone is a chronic (long-term) disorder that typically results in enlarged and deformed bones. Excessive bone breakdown and formation cause thick and fragile bone. As a result, bone pain, arthritis, noticeable deformities, and fractures can occur. The disease can affect any bone of the body, but is often found in the spine. The blood supply that feeds healthy nerve tissue may be diverted to the area of involved bone. Also, structural deformities of the involved vertebrae can cause narrowing of the spinal canal, producing a variety of neurological symptoms. (Source: excerpt from Questions and Answers About Spinal Stenosis: NIAMS)

Definitions of Paget's disease of bone:

Paget's Disease is a disease of bone that initially results in the excessive resorption of bone (by osteoclasts) followed by the replacement of normal bone marrow with vascular and fibrous tissue. (On-line Medical Dictionary) - (Source - Diseases Database)

A disease of bone occurring in the middle aged and elderly; excessive bone destruction sometimes leading to bone pain and fractures and skeletal deformities - (Source - WordNet 2.1)

Paget's disease of bone is listed as a "rare disease" by the Office of Rare Diseases (ORD) of the National Institutes of Health (NIH). This means that Paget's disease of bone, or a subtype of Paget's disease of bone, affects less than 200,000 people in the US population.
Source - National Institutes of Health (NIH)