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Causes of Parry Romberg Syndrome

Parry Romberg Syndrome Causes: Book Excerpts

Related information on causes of Parry Romberg Syndrome:

As with all medical conditions, there may be many causal factors. Further relevant information on causes of Parry Romberg Syndrome may be found in:

Causes of Parry Romberg Syndrome: Online Medical Books

16 MEDICAL BOOKS ONLINE! Review excerpts from medical books online, free, without registration, for more information about the causes of Parry Romberg Syndrome.

Romberg's Sign: Differential Diagnosis
(In a Page: Signs and Symptoms)

  • Myelopathy
    –Multiple sclerosis
    –Vitamin B12 deficiency
    –Structural spinal cord disease (e.g., spondolytic myelopathy, tumor)
    –Infectious myelopathy (e.g., tabes dorsalis, HIV-related vacuolar myelopathy)
  • Peripheral neuropathy: Affects large diameter, myelinated fibers
    –Vitamin B12 deficiency
    –CIDP
    –MGUS
    –Inherited demyelinating neuropathies (e.g., Charcot-Marie-Tooth disease)
    • Cerebellar dysfunction
      –Multiple causes (e.g., CVA, brain tumor)
      –Most patients with midline cerebellar dysfunction have difficulty standing on a narrow base; this effect will not appreciably worsen with eye closure
    • Vestibular dysfunction (peripheral)
      • Drug intoxication
        –Alcohol
        –Cisplatin
        –Pyridoxine (vitamin B6) overdose
        –Anticonvulsant toxicity (especially
        phenytoin) may cause difficulty standing on a narrow base, but this may not necessarily worsen with eye closure
      • Friedreich's ataxia
      • Miller-Fisher variant of Guillain-Barré syndrome
      • Paraneoplastic sensory neuropathy
      • Vitamin E deficiency

    » READ BOOK EXCERPT ONLINE »

    Source: In a Page: Signs and Symptoms, 2004

    Romberg's sign: Medical causes
    (Professional Guide to Signs & Symptoms (Fifth Edition))

    Multiple sclerosis

    Early features may include vision changes, diplopia, and paresthesia. Other findings include a positive Romberg’s sign, nystagmus, constipation, muscle weakness and spasticity, and hyperreflexia. The patient may also have dysphagia, dysarthria, incontinence, urinary frequency and urgency, impotence, and emotional instability.

    Peripheral nerve disease

    Besides a positive Romberg’s sign, advanced disease may produce impotence, fatigue, and paresthesia, hyperesthesia, or anesthesia in the hands and feet. Related findings include incoordination, ataxia, burning pain in the affected area, progressive muscle weakness and atrophy, and loss of vibration sense. DTRs may be hypoactive.

    Pernicious anemia

    A positive Romberg’s sign and loss of proprioception in the lower limbs reflect peripheral nerve and spinal cord damage. Gait changes (usually ataxia), muscle weakness, impaired coordination, paresthesia, and sensory loss may be present. DTRs may be hypoactive or hyperactive. Other findings include a sore tongue, a positive Babinski’s reflex, fatigue, blurred vision, diplopia, and light-headedness.

    Spinal cerebellar degeneration

    With this disorder, a positive Romberg’s sign accompanies decreased visual acuity, fatigue, paresthesia, loss of vibration sense, incoordination, ataxic gait, and muscle weakness and atrophy. DTRs may be hypoactive.

    Spinal cord disease

    A positive Romberg’s sign may accompany pain, fasciculations, muscle weakness and atrophy, loss of sphincter tone, and loss of proprioception, vibration, and other senses. DTRs may be hypoactive at the level of the lesion and hyperactive above it.

    Tabes dorsalis

    A positive Romberg’s sign may occur, but burning extremity pain is this disorder’s classic symptom. Other findings include a wide-based ataxic gait, loss of proprioception in the lower limbs (common), and loss of pain and temperature sensation. As the disease progresses, DTRs in the legs become hypoactive or absent, muscle tone decreases, and muscles atrophy. The patient may also develop Charcot’s joints and Argyll Robertson pupils.

    Vestibular disorders

    Besides a positive Romberg’s sign, these disorders commonly cause vertigo. Nystagmus, nausea, and vomiting may also occur.

    » READ BOOK EXCERPT ONLINE »

    Source: Professional Guide to Signs & Symptoms (Fifth Edition), 2006

    Romberg's sign: Medical causes
    (Signs & Symptoms: A 2-in-1 Reference for Nurses)

    Multiple sclerosis

    Early features of multiple sclerosis may include vision changes, diplopia, and paresthesia. Other findings include a positive Romberg’s sign, nystagmus, constipation, muscle weakness and spasticity, and hyperreflexia. The patient may also have dysphagia, dysarthria, incontinence, urinary frequency and urgency, impotence, and emotional instability.

    Peripheral nerve disease

    Besides a positive Romberg’s sign, advanced peripheral nerve disease may produce impotence, fatigue, and paresthesia, hyperesthesia, or anesthesia in the hands and feet. Related findings include incoordination, ataxia, burning pain in the affected area, progressive muscle weakness and atrophy, and loss of vibration sense. DTRs may be hypoactive.

    Pernicious anemia

    Pernicious anemia impairs myelin formation, which causes neurologic damage. A positive Romberg’s sign and loss of proprioception in the lower limbs reflect peripheral nerve and spinal cord damage. Gait changes (usually ataxia), muscle weakness, impaired coordination, paresthesia, and sensory loss may be present. DTRs may be hypoactive or hyperactive. Other findings include a sore tongue, a positive Babinski’s reflex, fatigue, blurred vision, diplopia, and light-headedness.

    Spinal cerebellar degeneration

    With spinal cerebellar degeneration, a positive Romberg’s sign accompanies decreased visual acuity, fatigue, paresthesia, loss of vibration sense, incoordination, ataxic gait, and muscle weakness and atrophy. DTRs may be hypoactive.

    Spinal cord disease

    With spinal cord disease, a positive Romberg’s sign may accompany pain, fasciculations, muscle weakness and atrophy, loss of sphincter tone, and loss of proprioception, vibration, and other senses. DTRs may be hypoactive at the level of the lesion and hyperactive above it.

    Vestibular disorders

    Besides a positive Romberg’s sign, vestibular disorders commonly cause vertigo. Nystagmus, nausea, tinnitus, hearing loss, and vomiting may also occur.

    » READ BOOK EXCERPT ONLINE »

    Source: Signs & Symptoms: A 2-in-1 Reference for Nurses, 2007


     » Next page: Symptoms of Parry Romberg Syndrome

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