The list of signs and symptoms mentioned in various sources for Pelizaeus-Merzbacher Disease includes the 16 symptoms listed below:
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Early symptoms may include slow growth, nystagmus (rapid, involuntary, rhythmic jerking of the eyes and the head), and failure to develop normal control of head movement. In adult-onset cases, deteriorating speech may be an early sign. Other symptoms may include tremor, various involuntary movements, grimacing, weakness, unsteady gait, and muscle contractures (shrinkage or shortening of a muscle). Over time, legs and arms may become spastic, and mental functions may deteriorate. Some patients may have convulsions and skeletal deformation, resulting from abnormal muscular stress on bones. (Source: excerpt from NINDS Pelizaeus-Merzbacher Disease Information Page: NINDS)
When considering symptoms of Pelizaeus-Merzbacher Disease, it is also important to consider Pelizaeus-Merzbacher Disease as a possible cause of other medical conditions. The Disease Database lists the following medical conditions that Pelizaeus-Merzbacher Disease may cause:
- (Source - Diseases Database)
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The symptom information on this page attempts to provide a list of some possible signs and symptoms of Pelizaeus-Merzbacher Disease. This signs and symptoms information for Pelizaeus-Merzbacher Disease has been gathered from various sources, may not be fully accurate, and may not be the full list of Pelizaeus-Merzbacher Disease signs or Pelizaeus-Merzbacher Disease symptoms. Furthermore, signs and symptoms of Pelizaeus-Merzbacher Disease may vary on an individual basis for each patient. Only your doctor can provide adequate diagnosis of any signs or symptoms and whether they are indeed Pelizaeus-Merzbacher Disease symptoms.
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