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Pemphigus Vulgaris



Introduction: Pemphigus Vulgaris

A rare autoimmune skin disorder involving blisters on the skin and on the mucous membranes such as in the mouth. Pemphigus is a group of autoimmune diseases involving the formation of fluid-filled blisters. Pemphigus vulgaris is a severe and often fatal form of pemphigus and occurs mostly in people aged between 40 and 60. The blisters tend to spread and join into each other and can seriously compromise the skin's protective barrier. Without treatment the condition can lead to complications such as sepsis and electrolyte imbalance which can ultimately lead to death.

Symptoms of Pemphigus Vulgaris

See full list of 20 symptoms of Pemphigus Vulgaris

Wrongly Diagnosed with Pemphigus Vulgaris?

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Prognosis for Pemphigus Vulgaris

Prognosis for Pemphigus Vulgaris: death within 2 years without treatment and 40% mortality with treatment

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Definitions of Pemphigus Vulgaris:

Pemphigus Vulgaris is listed as a "rare disease" by the Office of Rare Diseases (ORD) of the National Institutes of Health (NIH). This means that Pemphigus Vulgaris, or a subtype of Pemphigus Vulgaris, affects less than 200,000 people in the US population.
Source - National Institutes of Health (NIH)

Ophanet, a consortium of European partners, currently defines a condition rare when it affects 1 person per 2,000. They list Pemphigus Vulgaris as a "rare disease".
Source - Orphanet


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