Clinical Trials for Peripheral vascular disease

Clinical trials are research studies conducted in an effort to improve overall patient health and care. Each trial involves running supervised tests to determine the effectiveness and safety of new drugs, procedures and/or devices with the aim of answering scientific questions about a disease or condition. Risks and side-effects are also evaluated during these trials with results ranging from being unpleasant, with side effects such as headaches, to more serious or even life-threatening risks. A clinical trial may be separated into phases, or steps, with each step designed to answer a separate research question. This maybe reflected in the trial name.

A brief description of each phase:

• Phase I: Usually designed to evaluate safety, determine a safe dosage range, and identify side effects on a small group of patients.
• Phase II: If Phase I is successful, the trial is then repeated with a larger group to further evaluate its effect and safety.
• Phase III: Trials are conducted on an ever larger group and are compared with the best current treatment while gathering more information on effect and safety.
• Phase IV: These studies monitor long-term side effects after the treatment has been marketed.

Clinical Trials data for Peripheral vascular disease is grouped into the following categories:-

• View by trial name
• View by drugs used in Peripheral vascular disease clinical trials

Clinical Trials by trial name

The format for each of the following is:

• The name of the trial,
• followed by whether the trial is recruiting patients,
  - The trial may not have started and not yet recruiting, or the trial may have started and do not need any more recruitements, or the trial may be completed.
  - Note**: Please follow the link to determine the current trial status.
• followed by a list of drug/s, if any, used in the trial

ClinicalTrials.gov has listed the following trials for Peripheral vascular disease:

• Objective Evaluation of Proximal Ischemia - This study is currently recruiting patients (Current: 23 Nov 2006)
• Warfarin and Antiplatelet Vascular Evaluation - This study is no longer recruiting patients (Current: 23 Nov 2006) - Warfarin
• Magnetic Resonance Imaging to Detect Blood Vessel Inflammation in Patients Undergoing Peripheral Balloon Angioplasty - This study has been completed (Current: 23 Nov 2006)
• Study of Remodulin in Patients With Critical Limb Ischemia With No Planned Revascularization Procedures - This study has been terminated (Current: 23 Nov 2006) - Remodulin® (treprostinil sodium) Injection
• FIRE-PAD: Functional Improvement Through Revascularization of the Extremities for Peripheral Arterial Disease - This study is not yet open for patient recruitment (Current: 23 Nov 2006)
• Safety/Feasibility Study of HBOC-201 in Amputation at/Below Knee From Critical Lower Limb Ischemia - This study is currently recruiting patients (Current: 23 Nov 2006) - Hemoglobin-based oxygen carrier-201 (HBOC 201)
• Glycemic Control to Prevent Cardiac Morbidity in Vascular Surgery - This study is currently recruiting patients (Current: 23 Nov 2006) - continuous regular intravenous insulin infusion
• Prostaglandin E1 (Liprostin) Treatment With Lower Limb Angioplasty for Peripheral Arterial Occlusive Disease - This study is currently recruiting patients (Current: 23 Nov 2006) - Liprostin [liposomal Prostaglandin E1]
• Extract of Ginkgo Biloba (EGB 761) and Vascular Function - This study has been completed (Current: 23 Nov 2006) - Gingko Biloba (Herb)
• Prevention of Recurrent Venous Thromboembolism (PREVENT) - This study has been completed (Current: 23 Nov 2006) - warfarin
• Framingham Heart Study - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Etiology and Prevalence of Peripheral Arterial Disease - This study has been completed (Current: 23 Nov 2006)
• Health Professionals Follow-Up Study - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Incidence of Diabetes and Cardiovascular Disease in Mexican Americans - This study has been completed (Current: 23 Nov 2006)
• Natural History of Peripheral Arterial Disease - This study has been completed (Current: 23 Nov 2006)
• Homocysteine and Progression of Atherosclerosis - This study has been completed (Current: 23 Nov 2006)
• Epidemiology of Venous Disease - This study has been completed (Current: 23 Nov 2006)
• Blood Factors and Peripheral Arterial Disease Outcomes - This study has been completed (Current: 23 Nov 2006)
• Epidemiology of Venous Thromboembolism - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Prevention of Autogenous Vein Graft Failure in Peripheral Artery Bypass Procedures - This study has been completed (Current: 23 Nov 2006) - CGT003 (E2F Duplex Decoy)
• Mechanisms of Disability in Peripheral Arterial Disease - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Cardiac and Renal Disease Study (CARDS) - This study has been completed (Current: 23 Nov 2006)
• Gene-by-Smoking Interactions and Risk of Atherosclerosis - Ancillary to ARIC - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Alfimeprase for Thrombolysis in Acute Peripheral Arterial Occlusion - This study has been completed (Current: 23 Nov 2006) - Alfimeprase
• Improving Functioning in Peripheral Arterial Disease - This study is currently recruiting patients (Current: 23 Nov 2006)
• Safety Study of Using Stem Cells to Stimulate Development of New Blood Vessels in Peripheral Vascular Disease - This study is currently recruiting patients (Current: 23 Nov 2006) - adult stem cells
• Evaluation of the Zilver PTX Drug-Eluting Stent in the Above-the-Knee Femoropopliteal Artery - This study is currently recruiting patients (Current: 23 Nov 2006)
• Claudication: Exercise Versus Endoluminal Revascularization (CLEVER) - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Multicentric, Prospective, Randomized, Comparing Trial Between Bypass of the Femoropoplitea by PTFE and Heparin Bounded PTFE - This study is currently recruiting patients (Current: 23 Nov 2006)
• Mirror Trial - Follow-Up Management of Peripheral Arterial Intervention With Clopidogrel - This study is currently recruiting patients (Current: 23 Nov 2006) - clopidogrel
• The Burden of Peripheral Artery Occlusion Disease and Associated Factors in Peritoneal Dialysis Patients - This study is currently recruiting patients (Current: 23 Nov 2006)
• ASSESS Study: Evaluation of ABSOLUTE Stent System for Occluded Arteries - This study is currently recruiting patients (Current: 23 Nov 2006)
• GORE-TEX PROPATEN Vascular Graft Study - This study is currently recruiting patients (Current: 23 Nov 2006)
• Reducing Risk Factors in Peripheral Arterial Disease - This study is currently recruiting patients (Current: 23 Nov 2006)
• Stem Cell Study for Patients With Leg Ulcer/Gangrene - This study is currently recruiting patients (Current: 23 Nov 2006)
• Relation of Inflammation and Insulin Resistance to Peripheral Arterial Disease - This study is currently recruiting patients (Current: 23 Nov 2006) - Rosiglitazone,Atorvastatin
• GORE VIABAHN ENDOPROSTHESIS Peripheral Vascular Disease Study - This study is currently recruiting patients (Current: 23 Nov 2006)
• PROVIDENCE-1: Study of Rifalazil in Chlamydia Pneumoniae Seropositive Patients - This study is currently recruiting patients (Current: 23 Nov 2006) - Rifalazil
• L-Arginine in the Treatment of Peripheral Arterial Disease - This study is no longer recruiting patients (Current: 23 Nov 2006) - L-arginine
• Comparison Study of Vasovist Magnetic Resonance Angiography (MRA) and an MRA With a Conventional Extracellular Contrast Agent With X-Ray Angiography in Patients With Peripheral Artery Disease - This study is currently recruiting patients (Current: 23 Nov 2006) - Gadofosveset
• Autologous Bone Marrow Cell Treatment in Peripheral Atherosclerosis - This study is currently recruiting patients (Current: 23 Nov 2006)
• Intra-Arterial Stem Cell Therapy for Patients With Chronic Limb Ischemia (CLI) - This study is currently recruiting patients (Current: 23 Nov 2006)
• Understanding the Genetic Basis of Atherosclerosis and Peripheral Arterial Disease - This study is currently recruiting patients (Current: 23 Nov 2006)
• Safety and Efficacy of Proprionyl-L-Carnitine in the Treatment of Peripheral Arterial Disease (Intermittent Claudication) - This study is currently recruiting patients (Current: 23 Nov 2006) - Propionyl-L-Carnitine
• Efficacy/Safety of Ecraprost in Lipid Emulsion for Treatment of Critical Leg Ischemia Due to Peripheral Arterial Disease - This study has been terminated (Current: 23 Nov 2006) - Ecraprost in lipid emulsion
• Efficacy/Safety of Ecraprost in Lipid Emulsion for Treatment of Critical Leg Ischemia Due to Peripheral Arterial Disease - This study has been completed (Current: 23 Nov 2006) - Ecraprost in lipid emulsion
• Study of HGF Via Plasmid Vector to Improve Perfusion in Critical Limb Ischemia - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Effect of Niacin ER/Lovastatin on Peak Walking Time & Claudication Onset Time in Patients With Intermittent Claudication - This study is no longer recruiting patients (Current: 23 Nov 2006) - Niacin Extended Release and Lovastatin Tablets
• Effects of Remodulin in Patients With Critical Limb Ischemia Following a Vein Bypass Graft - This study has been terminated (Current: 23 Nov 2006) - Remodulin (treprostinil sodium) Injection
• Trial of VLTS-589 in Subjects With Intermittent Claudication - This study has been completed (Current: 23 Nov 2006)
• The Dose Response of Niacin ER/Lovastatin on Peak Walking Time (PWT) in Patients With Intermittent Claudication - TROPIC - This study is currently recruiting patients (Current: 23 Nov 2006) - Niacin Extended Release and Lovastatin Tablets
• Efficacy and Safety of NM-702 Tablets for the Treatment of Intermittent Claudication - This study has been completed (Current: 23 Nov 2006) - NM-702 (phosphodiesterase inhibitor)
• Trial of VLTS-934 in Subjects With Intermittent Claudication Secondary to Peripheral Arterial Disease - This study is no longer recruiting patients (Current: 23 Nov 2006) - VLTS-934
• Safety and Efficacy Study of Ad2/Hypoxia Inducible Factor (HIF)-1/VP16 Gene Transfer in Patients With Intermittent Claudication - This study is currently recruiting patients (Current: 23 Nov 2006)
• Evaluation of Fibrin Sealant 2 in Vascular Surgical Procedures - This study has been completed (Current: 23 Nov 2006) - Fibrin sealant (FS2)
• Study of Hepatocyte Growth Factor (HGF) Via Plasmid Vector to Improve Perfusion in Critical Limb Ischemia Patients With Peripheral Ischemic Ulcers - This study is currently recruiting patients (Current: 23 Nov 2006)
• The Effects of Physical Training, ASA and Clopidogrel on the Walking Capacity of Patients With Stage II PAD - This study is currently recruiting patients (Current: 23 Nov 2006) - Aspirin,Clopidogrel
• Oslo Balloon Angioplasty Versus Conservative Treatment - This study has been completed (Current: 23 Nov 2006)
• How Does Early Age Life Style Affect Bone Strength and General Health Parameters at Middle Age? - This study is not yet open for patient recruitment (Current: 23 Nov 2006)
• Stem Cell Transplantation for Peripheral Vascular Disease - This study is currently recruiting patients (Current: 23 Nov 2006)
• Testosterone Replacement in Diabetes With Vascular Disease (Version 2) - This study is currently recruiting patients (Current: 23 Nov 2006) - Testosterone
• Systematic Assessment of Vascular Risk - This study is currently recruiting patients (Current: 23 Nov 2006)
• RESTORE-IT-Study of Rifalazil in Chlamydia Pneumoniae Seropositive Patients With a History of Atherosclerotic Disease. - This study is currently recruiting patients (Current: 23 Nov 2006) - Rifalazil
• Efficacy Study of Oral L-Citrulline in Patients Taking Simvastatin With Peripheral Arterial Disease - This study is no longer recruiting patients (Current: 23 Nov 2006) - L-citrulline tablets, 1000 mg,Placebo tablets matching L-citrulline tablets,Background simvastatin at a stable dose of 40 mg qHS
• SIMPADICO - Study of Immune Modulation Therapy in Peripheral Arterial Disease and Intermittent Claudication Outcomes - This study has been terminated (Current: 23 Nov 2006)
• Multifactorial Intervention on Cardiovascular Risk Factors in Subjects With Peripheral Arterial Disease - This study is no longer recruiting patients (Current: 23 Nov 2006) - Stepwise therapy for dyslipidemia, hypertension and diabetes
• Evaluation of FM220 in Patients With Peripheral Arterial Disease (PAD) - This study is currently recruiting patients (Current: 23 Nov 2006)
• The Effects of Ramipril on Clinical Symptoms in Patients With Peripheral Arterial Disease - This study has been completed (Current: 23 Nov 2006) - Ramipril
• Non-Invasive Cardiac Screening in High Risk Patients -The GROUND Study - This study is currently recruiting patients (Current: 23 Nov 2006)
• Evaluation of the Zilver Vascular Stent in the Iliac Arteries (ZIPS) - This study has been completed (Current: 23 Nov 2006)
• Measurement of Tissue Oxygen Saturation in Chronic Critical Limb Ischemia - This study is currently recruiting patients (Current: 23 Nov 2006)
• Safety and Feasibility Study of Autologous Bone Marrow Cell Transplantation in Patients With PAOD - This study is currently recruiting patients (Current: 23 Nov 2006)
• The SIT-UP Study: Swiss Investigation of the S.M.A.R.T. Nitinol Self-Expandable Stent in Superficial Femoral Artery Occlusions Versus Balloon Angioplasty. - This study is currently recruiting patients (Current: 23 Nov 2006)
• Efficacy and Safety Study of NV1FGF in Patients With Severe Peripheral Artery Occlusive Disease. - This study has been completed (Current: 23 Nov 2006) - XRP0038 (NV1FGF)
• Safety Study of MultiGeneAngio in Patients With Peripheral Arterial Disease (PAD) - This study is currently recruiting patients (Current: 23 Nov 2006)
• EW-A-401 to Treat Intermittent Claudication - This study is currently recruiting patients (Current: 23 Nov 2006) - EW-A-401 DNA Plasmid Vector,DNA Plasmid Vector
• Safety & Efficacy of a Combination Niacin ER/Simvastatin in Patients With Dyslipidemia: A Dose-Ranging Study - SEACOAST - This study is no longer recruiting patients (Current: 23 Nov 2006) - Niacin extended release and simvastatin tablets
• Rio Trial - ReoPro and Peripheral Arterial Intervention to Improve Clinical Outcome in Patients With Peripheral Arterial Disease - This study is currently recruiting patients (Current: 23 Nov 2006) - Balloon Angioplasty
• Thunder Trial - Local Taxan With Short Time Contact for Reduction of Restenosis in Distal Arteries - This study is no longer recruiting patients (Current: 23 Nov 2006) - Balloon Angioplasty with or without drug administration

Drugs used in Clinical Trials for Peripheral vascular disease

The format for each of the following is:

• The drug,
• followed by the name of the trial,
• followed by whether the trial is recruiting patients,
  - The trial may not have started and not yet recruiting, or the trial may have started and do not need any more recruitements, or the trial may be completed.
  - Note**: Please follow the link to determine the current trial status.

ClinicalTrials.gov has listed the following drugs in trials for Peripheral vascular disease:

• Adult Stem Cells - Safety Study of Using Stem Cells to Stimulate Development of New Blood Vessels in Peripheral Vascular Disease - This study is currently recruiting patients (Current: 23 Nov 2006)
• Alfimeprase - Alfimeprase for Thrombolysis in Acute Peripheral Arterial Occlusion - This study has been completed (Current: 23 Nov 2006)
• Aspirin - The Effects of Physical Training, ASA and Clopidogrel on the Walking Capacity of Patients With Stage II PAD - This study is currently recruiting patients (Current: 23 Nov 2006)
• Atorvastatin - Relation of Inflammation and Insulin Resistance to Peripheral Arterial Disease - This study is currently recruiting patients (Current: 23 Nov 2006)
• Background simvastatin at a stable dose of 40 mg qHS - Efficacy Study of Oral L-Citrulline in Patients Taking Simvastatin With Peripheral Arterial Disease - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Balloon Angioplasty with or without drug administration - Thunder Trial - Local Taxan With Short Time Contact for Reduction of Restenosis in Distal Arteries - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Balloon Angioplasty - Rio Trial - ReoPro and Peripheral Arterial Intervention to Improve Clinical Outcome in Patients With Peripheral Arterial Disease - This study is currently recruiting patients (Current: 23 Nov 2006)
• CGT003 (E2F Duplex Decoy) - Prevention of Autogenous Vein Graft Failure in Peripheral Artery Bypass Procedures - This study has been completed (Current: 23 Nov 2006)
• Clopidogrel - Mirror Trial - Follow-Up Management of Peripheral Arterial Intervention With Clopidogrel - This study is currently recruiting patients (Current: 23 Nov 2006)
• Clopidogrel - The Effects of Physical Training, ASA and Clopidogrel on the Walking Capacity of Patients With Stage II PAD - This study is currently recruiting patients (Current: 23 Nov 2006)
• Continuous Regular Intravenous Insulin Infusion - Glycemic Control to Prevent Cardiac Morbidity in Vascular Surgery - This study is currently recruiting patients (Current: 23 Nov 2006)
• DNA Plasmid Vector - EW-A-401 to Treat Intermittent Claudication - This study is currently recruiting patients (Current: 23 Nov 2006)
• EW-A-401 DNA Plasmid Vector - EW-A-401 to Treat Intermittent Claudication - This study is currently recruiting patients (Current: 23 Nov 2006)
• Ecraprost in lipid emulsion - Efficacy/Safety of Ecraprost in Lipid Emulsion for Treatment of Critical Leg Ischemia Due to Peripheral Arterial Disease - This study has been terminated (Current: 23 Nov 2006)
• Ecraprost in lipid emulsion - Efficacy/Safety of Ecraprost in Lipid Emulsion for Treatment of Critical Leg Ischemia Due to Peripheral Arterial Disease - This study has been completed (Current: 23 Nov 2006)
• Fibrin sealant (FS2) - Evaluation of Fibrin Sealant 2 in Vascular Surgical Procedures - This study has been completed (Current: 23 Nov 2006)
• Gadofosveset - Comparison Study of Vasovist Magnetic Resonance Angiography (MRA) and an MRA With a Conventional Extracellular Contrast Agent With X-Ray Angiography in Patients With Peripheral Artery Disease - This study is currently recruiting patients (Current: 23 Nov 2006)
• Gingko Biloba (Herb) - Extract of Ginkgo Biloba (EGB 761) and Vascular Function - This study has been completed (Current: 23 Nov 2006)
• Hemoglobin-based oxygen carrier-201 (HBOC 201) - Safety/Feasibility Study of HBOC-201 in Amputation at/Below Knee From Critical Lower Limb Ischemia - This study is currently recruiting patients (Current: 23 Nov 2006)
• L-arginine - L-Arginine in the Treatment of Peripheral Arterial Disease - This study is no longer recruiting patients (Current: 23 Nov 2006)
• L-citrulline tablets, 1000 mg - Efficacy Study of Oral L-Citrulline in Patients Taking Simvastatin With Peripheral Arterial Disease - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Liprostin [liposomal Prostaglandin E1] - Prostaglandin E1 (Liprostin) Treatment With Lower Limb Angioplasty for Peripheral Arterial Occlusive Disease - This study is currently recruiting patients (Current: 23 Nov 2006)
• NM-702 (phosphodiesterase inhibitor) - Efficacy and Safety of NM-702 Tablets for the Treatment of Intermittent Claudication - This study has been completed (Current: 23 Nov 2006)
• Niacin Extended Release and Lovastatin Tablets - Effect of Niacin ER/Lovastatin on Peak Walking Time & Claudication Onset Time in Patients With Intermittent Claudication - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Niacin Extended Release and Lovastatin Tablets - The Dose Response of Niacin ER/Lovastatin on Peak Walking Time (PWT) in Patients With Intermittent Claudication - TROPIC - This study is currently recruiting patients (Current: 23 Nov 2006)
• Niacin extended release and simvastatin tablets - Safety & Efficacy of a Combination Niacin ER/Simvastatin in Patients With Dyslipidemia: A Dose-Ranging Study - SEACOAST - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Placebo tablets matching L-citrulline tablets - Efficacy Study of Oral L-Citrulline in Patients Taking Simvastatin With Peripheral Arterial Disease - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Propionyl-L-Carnitine - Safety and Efficacy of Proprionyl-L-Carnitine in the Treatment of Peripheral Arterial Disease (Intermittent Claudication) - This study is currently recruiting patients (Current: 23 Nov 2006)
• Ramipril - The Effects of Ramipril on Clinical Symptoms in Patients With Peripheral Arterial Disease - This study has been completed (Current: 23 Nov 2006)
• Remodulin (treprostinil sodium) Injection - Effects of Remodulin in Patients With Critical Limb Ischemia Following a Vein Bypass Graft - This study has been terminated (Current: 23 Nov 2006)
• Remodulin® (treprostinil sodium) Injection - Study of Remodulin in Patients With Critical Limb Ischemia With No Planned Revascularization Procedures - This study has been terminated (Current: 23 Nov 2006)
• Rifalazil - PROVIDENCE-1: Study of Rifalazil in Chlamydia Pneumoniae Seropositive Patients - This study is currently recruiting patients (Current: 23 Nov 2006)
• Rifalazil - RESTORE-IT-Study of Rifalazil in Chlamydia Pneumoniae Seropositive Patients With a History of Atherosclerotic Disease. - This study is currently recruiting patients (Current: 23 Nov 2006)
• Rosiglitazone - Relation of Inflammation and Insulin Resistance to Peripheral Arterial Disease - This study is currently recruiting patients (Current: 23 Nov 2006)
• Stepwise therapy for dyslipidemia, hypertension and diabetes - Multifactorial Intervention on Cardiovascular Risk Factors in Subjects With Peripheral Arterial Disease - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Testosterone - Testosterone Replacement in Diabetes With Vascular Disease (Version 2) - This study is currently recruiting patients (Current: 23 Nov 2006)
• VLTS-934 - Trial of VLTS-934 in Subjects With Intermittent Claudication Secondary to Peripheral Arterial Disease - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Warfarin - Prevention of Recurrent Venous Thromboembolism (PREVENT) - This study has been completed (Current: 23 Nov 2006)
• Warfarin - Warfarin and Antiplatelet Vascular Evaluation - This study is no longer recruiting patients (Current: 23 Nov 2006)
• XRP0038 (NV1FGF) - Efficacy and Safety Study of NV1FGF in Patients With Severe Peripheral Artery Occlusive Disease. - This study has been completed (Current: 23 Nov 2006)

The trial data on this page has been sourced from

• The U.S. National Library of Medicine (NLM) together with ClinicalTrials.gov

 » Next page: External links relating to Peripheral vascular disease

Rate This Website

What do you think about the features of this website? Take our user survey and have your say:

Website User Survey

Medical Tools & Articles:

Next articles:

• External links relating to Peripheral vascular disease
• Surveys relating to Peripheral vascular disease
• Ask Question about Peripheral vascular disease

Tools & Services:

• Bookmark this page
• Take a survey relating to Peripheral vascular disease
• Symptom Search
• Symptom Checker
• Medical Dictionary
• Give your feedback

Medical Articles:

• Disease & Treatments Search
• Misdiagnosis Center
• Full list of interesting articles

Forums & Message Boards

• Ask or answer a question at the Boards:
• I cannot get a diagnosis. Please help.
• Tell us your medical story.
• Share your misdiagnosis story.
• What is the best treatment for my condition?
• See all the Boards.

Enter your search terms Submit search form
Search The Web Search wrongdiagnosis.com

Common Health Mistakes

Symptom
Checker

Search Specialists by State and City