Following is a list of causes or underlying conditions (see also Misdiagnosis of underlying causes of Peyronie's disease) that could possibly cause Peyronie's disease includes:
The following drugs, medications, substances or toxins are some of the possible
causes of Peyronie's disease as a symptom.
This list is incomplete and various other drugs or substances
may cause your symptoms.
Always advise your doctor of any medications or treatments you are using,
including prescription, over-the-counter, supplements, herbal or alternative treatments.
See full list of 10 medications causing Peyronie's disease
Causes: Peyronie's disease:
Many researchers believe the plaque of
Peyronie's disease develops following trauma (hitting or bending) that
causes localized bleeding inside the penis.
(Source: excerpt from Peyronie's Disease: NIDDK)
Article excerpts about the
causes of Peyronie's disease:
Many researchers believe the plaque of
Peyronie's disease develops following trauma (hitting or bending) that
causes localized bleeding inside the penis.
Two chambers known as the
corpora cavernosa run the length of the penis. The inner-surface
membrane of the chambers is a sheath of elastic fibers. A connecting
tissue, called a septum, runs along the center of each chamber and
attaches at the top and bottom.
If the penis is abnormally bumped or bent, an area where the septum attaches to the elastic fibers may stretch beyond a limit, injuring the lining of the erectile chamber and, for example, rupturing small blood vessels. As a result of aging, diminished elasticity near the point of attachment of the septum might increase the chances of injury.
The damaged area might heal slowly or abnormally for two reasons: repeated trauma and a minimal amount of blood flow in the sheath-like fibers. In cases that heal within about a year, the plaque does not advance beyond an initial inflammatory phase. In cases that persist for years, the plaque undergoes fibrosis, or formation of tough fibrous tissue, and even calcification, or formation of calcium deposits.
While trauma might explain acute cases of Peyronie's disease, it does not explain why most cases develop slowly and with no apparent traumatic event. It also does not explain why some cases disappear quickly, and why similar conditions such as Dupuytren's contracture do not seem to result from severe trauma.
Some researchers theorize that Peyronie's disease may be an autoimmune disorder. (Source: excerpt from Peyronie's Disease: NIDDK)
As with all medical conditions, there may be many causal factors. Further relevant information on causes of Peyronie's disease may be found in:
16 MEDICAL BOOKS ONLINE! Review excerpts from medical books online, free, without registration, for more information about the causes of Peyronie's disease.
These clinical types of cirrhosis reflect its diverse etiology:
❑ Portal, nutritional, or alcoholic (Laennec’s) cirrhosis, the most common type, occurs in 30% to 50% of cirrhotic patients, up to 90% of whom have a history of alcoholism. Liver damage results from malnutrition, especially of dietary protein, and chronic alcohol ingestion. Fibrous tissue forms in portal areas and around central veins.
❑ Biliary cirrhosis (15% to 20% of patients) results from injury or prolonged obstruction.
❑ Postnecrotic (posthepatic) cirrhosis (10% to 30% of patients) stems from various types of hepatitis.
❑ Pigment cirrhosis (5% to 10% of patients) may result from disorders such as hemochromatosis.
❑ Cardiac cirrhosis (rare) refers to liver damage caused by right-sided heart failure.
❑ Idiopathic cirrhosis (about 10% of patients) has no known cause.
Noncirrhotic fibrosis may result from schistosomiasis or congenital hepatic fibrosis or may be idiopathic.
Source: Professional Guide to Diseases (Eighth Edition), 2005
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