Treatments for Pituitary conditions
Hospital statistics for Pituitary conditions:
These medical statistics relate to hospitals, hospitalization and Pituitary conditions:
- 0.016% (2,061) of hospital consultant episodes were for hypofunction and other disorders of pituitary gland in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03)
- 94% of hospital consultant episodes for hypofunction and other disorders of pituitary gland required hospital admission in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03)
- 54% of hospital consultant episodes for hypofunction and other disorders of pituitary gland were for men in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03)
- 46% of hospital consultant episodes for hypofunction and other disorders of pituitary gland were for women in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03)
- 14% of hospital consultant episodes for hypofunction and other disorders of pituitary gland required emergency hospital admission in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03)
- more hospital information...»
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Diabetes insipidus:
Treatment
(Professional Guide to Diseases (Eighth Edition))
Mild cases require no treatment other than fluid intake to replace fluid lost. Until the cause of more severe cases of diabetes insipidus can be identified and eliminated, administration of various forms of vasopressin or of a vasopressin stimulant can control fluid balance and prevent dehydration. Vasopressin injection is an aqueous preparation that’s administered S.C. or I.M. several times a day because it’s effective for only 2 to 6 hours; this form of the drug is used in acute disease and as a diagnostic agent.
Desmopressin acetate can be given by nasal spray that’s absorbed through the mucous membranes, or by injection given S.C. or I.V.; this drug is effective for 8 to 20 hours, depending on the dosage. It’s also available in tablet form, to be given at bedtime or in divided doses. Hydrochlorothiazide can be used in both central and nephrogenic diabetes insipidus. Indomethacin and amiloride are also used for nephrogenic diabetes insipidus. If nephrogenic diabetes insipidus is caused by medication (such as lithium), stopping the medicine leads to kidney recovery.
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Source: Professional Guide to Diseases (Eighth Edition), 2005
Pituitary tumors:
Treatment
(Professional Guide to Diseases (Eighth Edition))
Surgical options include transfrontal removal of large tumors impinging on the optic apparatus and transsphenoidal resection for smaller tumors confined to the pituitary fossa. (See Transsphenoidal pituitary surgery.)
Radiation is the primary treatment for small, nonsecretory tumors that don't extend beyond the sella turcica or for patients who may be poor postoperative risks; otherwise, it's an adjunct to surgery.
Postoperative treatment includes hormone replacement with cortisone, thyroid, and sex hormones; correction of electrolyte imbalance; and, as necessary, insulin therapy.
Drug therapy may include bromocriptine, an ergot derivative that shrinks prolactin- and GH-secreting tumors. Cyproheptadine, an antiserotonin drug, can reduce increased corticosteroid levels in the patient with Cushing's syndrome.
Adjuvant radiation therapy is used when only partial removal of the tumor is possible. Cryohypophysectomy (freezing the area with a probe inserted by transsphenoidal route) is a promising alternative to surgical dissection of the tumor.
» READ BOOK EXCERPT ONLINE »
Source: Professional Guide to Diseases (Eighth Edition), 2005
Diabetes insipidus:
Treatment
(Handbook of Diseases)
Until the cause of diabetes insipidus can be identified and eliminated, administration of various forms of vasopressin can control fluid balance and prevent dehydration.
Vasopressin injection
This aqueous preparation is administered S.C. or I.M. several times a day because it’s effective for only 2 to 6 hours. This form of the drug is used as a diagnostic agent and, rarely, in acute disease.
Desmopressin acetate
This drug can be given orally, by nasal spray that’s absorbed through the mucous membranes or by S.C. or I.V. injection. Desmopressin acetate is effective for 8 to 20 hours, depending on the dosage.
» READ BOOK EXCERPT ONLINE »
Source: Handbook of Diseases, 2003
Pituitary tumors:
Treatment
(Handbook of Diseases)
Surgical options include transfrontal removal of large tumors impinging on the optic apparatus and transsphenoidal resection for smaller tumors confined to the pituitary fossa. (See Transsphenoidal pituitary surgery.) Radiation is the primary treatment for small, nonsecretory tumors that don’t extend beyond the sella turcica and for patients who may be poor postoperative risks; otherwise, it’s an adjunct to surgery.
Postoperative treatment includes hormone replacement with cortisone, thyroid, and sex hormones; correction of electrolyte imbalance; and, as necessary, insulin therapy.
Drug therapy may include bromo-criptine, an ergot derivative that shrinks prolactin-secreting and growth hormone-secreting tumors. Antiserotonin drugs can reduce increased corticosteroid levels in the patient with Cushing’s syndrome.
Adjuvant radiotherapy is used when only partial removal of the tumor is possible. Cryohypophysectomy (freezing the area with a probe inserted by transsphenoidal route) is a promising alternative to surgical dissection of the tumor.
» READ BOOK EXCERPT ONLINE »
Source: Handbook of Diseases, 2003
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